Author : Thomas F. Lee
Publisher : Springer
Page : 322 pages
File Size : 42,19 MB
Release : 2013-12-11
Category : Medical
ISBN : 1489960228
Describes the ten-year, multimillion dollar Human Genome Project and its process of gene mapping; includes concerns of critics of the project.
Author : National Research Council
Publisher : National Academies Press
Page : 128 pages
File Size : 39,34 MB
Release : 1988-01-01
Category : Science
ISBN : 0309038405
There is growing enthusiasm in the scientific community about the prospect of mapping and sequencing the human genome, a monumental project that will have far-reaching consequences for medicine, biology, technology, and other fields. But how will such an effort be organized and funded? How will we develop the new technologies that are needed? What new legal, social, and ethical questions will be raised? Mapping and Sequencing the Human Genome is a blueprint for this proposed project. The authors offer a highly readable explanation of the technical aspects of genetic mapping and sequencing, and they recommend specific interim and long-range research goals, organizational strategies, and funding levels. They also outline some of the legal and social questions that might arise and urge their early consideration by policymakers.
Author : Charles R. Cantor
Publisher : John Wiley & Sons
Page : 621 pages
File Size : 16,68 MB
Release : 2004-01-06
Category : Science
ISBN : 0471461865
A unique exploration of the principles and methods underlying the Human Genome Project and modern molecular genetics and biotechnology-from two top researchers In Genomics, Charles R. Cantor, former director of the Human Genome Project, and Cassandra L. Smith give the first integral overview of the strategies and technologies behind the Human Genome Project and the field of molecular genetics and biotechnology. Written with a range of readers in mind-from chemists and biologists to computer scientists and engineers-the book begins with a review of the basic properties of DNA and the chromosomes that package it in cells. The authors describe the three main techniques used in DNA analysis-hybridization, polymerase chain reaction, and electrophoresis-and present a complete exploration of DNA mapping in its many different forms. By explaining both the theoretical principles and practical foundations of modern molecular genetics to a wide audience, the book brings the scientific community closer to the ultimate goal of understanding the biological function of DNA. Genomics features: * Topical organization within chapters for easy reference * A discussion of the developing methods of sequencing, such as sequencing by hybridization (SBH) in which data is read through words instead of letters * Detailed explanations and critical evaluations of the many different types of DNA maps that can be generated-including cytogenic and restriction maps as well as interspecies cell hybrids * Informed predictions for the future of DNA sequencing
Author : Aine Donovan
Publisher : UPNE
Page : 206 pages
File Size : 20,55 MB
Release : 2008
Category : Education
ISBN : 9781584656951
Begun formally in 1990, the U.S. Human Genome Project's (HGP) goals were to identify all the 20,000 to 25,000 genes in human DNA, determine the sequences of the three billion chemical base pairs that make up human DNA, store this information in databases, improve tools for data analysis, and transfer related technologies to the private sector. It was the first large scientific undertaking to address potential issues that arose from project data, and opened up vast possibilities for the use of genetic data and the alteration of our genetic makeup. This volume is the first to address the diverse range of ethical issues arising from the HGP, and enables professors to bring this critically important topic to life in the classroom. ';
Author : Daniel J. Kevles
Publisher : Harvard University Press
Page : 420 pages
File Size : 30,12 MB
Release : 1992
Category : Medical
ISBN : 9780674136465
Provided by Horace Freeland Judson, author of the bestselling Eighth Day of Creation. The book's broad and balanced coverage and the expertise of its contributors make The Code of Codes the most comprehensive and compelling exploration available on this history-making project.
Author : Kevin Davies
Publisher : JHU Press
Page : 358 pages
File Size : 25,86 MB
Release : 2002-10
Category : Medical
ISBN : 9780801871405
This newly updated edition sheds light on the secrets of the sequence, highlighting the myriad ways in which genomics will impact human health for generations to come.
Author : National Research Council
Publisher : National Academies Press
Page : 348 pages
File Size : 46,16 MB
Release : 2000-12-21
Category : Nature
ISBN : 0309070864
Scientific Frontiers in Developmental Toxicology and Risk Assessment reviews advances made during the last 10-15 years in fields such as developmental biology, molecular biology, and genetics. It describes a novel approach for how these advances might be used in combination with existing methodologies to further the understanding of mechanisms of developmental toxicity, to improve the assessment of chemicals for their ability to cause developmental toxicity, and to improve risk assessment for developmental defects. For example, based on the recent advances, even the smallest, simplest laboratory animals such as the fruit fly, roundworm, and zebrafish might be able to serve as developmental toxicological models for human biological systems. Use of such organisms might allow for rapid and inexpensive testing of large numbers of chemicals for their potential to cause developmental toxicity; presently, there are little or no developmental toxicity data available for the majority of natural and manufactured chemicals in use. This new approach to developmental toxicology and risk assessment will require simultaneous research on several fronts by experts from multiple scientific disciplines, including developmental toxicologists, developmental biologists, geneticists, epidemiologists, and biostatisticians.
Author : Kelly E. Happe
Publisher : NYU Press
Page : 304 pages
File Size : 12,54 MB
Release : 2013-05-06
Category : Social Science
ISBN : 0814790674
In 2000, the National Human Genome Research Institute announced the completion of a “draft” of the human genome, the sequence information of nearly all 3 billion base pairs of DNA. In the wake of this major scientific accomplishment, the focus on the genetic basis of disease has sparked many controversies as questions are raised about radical preventative therapies, the role of race in research, and the environmental origins of illness. In The Material Gene, Kelly Happe explores the cultural and social dimensions of our understandings of genomics, using this emerging field to examine the physical manifestation of social relations. Situating contemporary genomics medicine and public health within a wider history of eugenics, Happe examines how the relationship between heredity and dominant social and economic interests has shifted along with transformations in gender and racial politics, social movement, and political economy. Happe demonstrates that genomics is a type of social knowledge, relying on cultural values to attach meaning to the body. The Material Gene situates contemporary genomics within a history of genetics research yet is attentive to the new ways in which knowledge claims about heredity, race, and gender emerge and are articulated to present-day social and political agendas. Kelly E. Happe is assistant professor of communication studies and women’s studies at the University of Georgia.
Author :
Publisher :
Page : 0 pages
File Size : 33,38 MB
Release : 1992
Category : Human gene mapping
ISBN :
Author : Julia E. Richards
Publisher : Academic Press
Page : 600 pages
File Size : 38,27 MB
Release : 2010-12-12
Category : Science
ISBN : 0080918654
Significant advances in our knowledge of genetics were made during the twentieth century but in the most recent decades, genetic research has dramatically increased its impact throughout society. Genetic issues are now playing a large role in health and public policy, and new knowledge in this field will continue to have significant implications for individuals and society. Written for the non-majors human genetics course, Human Genetics, Third Edition will increase the genetics knowledge of students who are learning about human genetics for the first time. This thorough revision of the best-selling Human Genome, Second Edition includes entirely new chapters on forensics, stem cell biology, bioinformatics, and societal/ethical issues associated with the field. New special features boxes make connections between human genetics and human health and disease. Carefully crafted pedagogy includes chapter-opening case studies that set the stage for each chapter; concept statements interspersed throughout the chapter that keep first-time students focused on key concepts; and end-of-chapter questions and critical thinking activities. This new edition will contribute to creating a genetically literate student population that understands basic biological research, understands elements of the personal and health implications of genetics, and participates effectively in public policy issues involving genetic information. - Includes topical material on forensics, disease studies, and the human genome project to engage non-specialist students - Full, 4-color illustration program enhances and reinforces key concepts and themes - Uniform organization of chapters includes interest boxes that focus on human health and disease, chapter-opening case studies, and concept statements to engage non-specialist readers
