Imaging in Photodynamic Therapy


Book Description

This book covers the broad field of cellular, molecular, preclinical, and clinical imaging either associated with or combined with photodynamic therapy (PDT). It showcases how this approach is used clinically for cancer, infections, and diseases characterized by unwanted tissue such as atherosclerosis or blindness. Because the photosensitizers are also fluorescent, the book also addresses various imaging systems such as confocal microscopy and small animal imaging systems, and highlights how they have been used to follow and optimize treatment, and to answer important mechanistic questions. Chapters also discuss how imaging has made important contributions to clinical outcomes in skin, bladder, and brain cancers, as well as in the development of theranostic agents for detection and treatment of disease. This book provides a resource for physicians and research scientists in cell biology, microscopy, optics, molecular imaging, oncology, and drug discovery.




Semiconductor Quantum Dots And Rods For In Vivo Imaging And Cancer Phototherapy


Book Description

Cancer is fast becoming one of the main causes of death worldwide. Unfortunately many cases are diagnosed at an advanced incurable stage, and these lives are usually lost. Early diagnosis and treatment are very important for increasing disease curability. In recent years, novel techniques for cancer diagnosis and therapy have been developed, and nanobiomedicine appears to show the most promising results.The application of nanotechnology to biology and medicine in cancer diagnosis is termed nanobiomedicine. Nanoparticles 1-100 nm in size usually have unique physical and/or chemical properties, and this has attracted great attention in the cancer research. Preparation and biomedical applications of the nanoparticles are key components in nanobiomedicine. Semiconductor nanocrystals, including quantum dots (QDs) and quantum rods (QRs), have been extensively investigated for drug delivery, biomedical imaging and tumor target therapy.In Semiconductor Quantum Dots and Rods for In Vivo Imaging and Cancer Phototherapy, the QD and QR optical properties, sentinel lymph node mapping, in vivo tumor target imaging, self-illuminating QDs for in vivo imaging, in vivo cancer photothermal therapy and photodynamic therapy, QD-graphene nanosheet, and QD-magnetic hybrid nanocomposites for bioimaging and cancer therapy are discussed. This book may interest under- and postgraduate students in the field of bioengineering (especially cancer phototherapy) and medical professions alike.




Photonanotechnology for Therapeutics and Imaging


Book Description

Photonanotechnology for Therapeutics and Imaging surveys major concepts and recent advances in the use of photonanotechnology with nanomaterials reported in various interdisciplinary fields, including chemistry, materials science, biomedical engineering and biomedicine. This book discusses the impact of this technology on the advancement of therapeutic modalities and imaging methods in cancers, infectious diseases and other serious diseases. Photonanotechnology studies the design principle, application and development of photoactive nanomaterials. It applies light-controlled strategies for the development of nanotherapeutics, imaging agents and diagnostic nanodevices. - Provides the latest information on photocontrolled drug delivery systems - Details how photoactive nanomaterials are designed to release reactive oxygen species (ROS) for photodynamic therapy (PDT) - Explains how photoactive nanomaterials have the ability to induce surface plasmonic heating for photothermal therapeutic (PTT) effects




Applications of Nanoscience in Photomedicine


Book Description

Nanoscience has become one of the key growth areas in recent years. It can be integrated into imaging and therapy to increase the potential for novel applications in the field of photomedicine. In the past commercial applications of nanoscience have been limited to materials science research only, however, in recent years nanoparticles are rapidly being incorporated into industrial and consumer products. This is mainly due to the expansion of biomedical related research and the burgeoning field of nanomedicine. Applications of Nanoscience in Photomedicine covers a wide range of nanomaterials including nanoparticles used for drug delivery and other emerging fields such as optofluidics, imaging and SERS diagnostics. Introductory chapters are followed by a section largely concerned with imaging, and finally a section on nanoscience-enabled therapeutics. - Covers a comprehensive up-to-date information on nanoscience - Focuses on the combination of photomedicine with nanotechnology to enhance the diversity of applications - Pioneers in the field have written their respective chapters - Opens a plethora of possibilities for developing future nanomedicine - Easy to understand and yet intensive coverage chapter by chapter




Advances in Photodynamic Therapy


Book Description

With today's focus on targeted and minimally invasive therapies, photodynamic therapy (PDT) is now being studied and used to combat many disease states and to investigate critical biological questions. This groundbreaking resource brings you the latest advances in photodynamic therapy and offers you a solid understanding of the design, delivery and dosimetry of the three basic ingredients of PDT - photosensitizers, light and oxygen. The book covers novel areas of mechanistic and innovative translational approaches. Moreover, it gives you an overview of the important medical applications of PDT, including approved treatments, clinical trials, and investigated therapies for cancer and non-malignant diseases.




Handbook of Photomedicine


Book Description

Providing the most comprehensive, up-to-date coverage of this exciting biomedical field, Handbook of Photomedicine gathers together a large team of international experts to give you a complete account of the application of light in healthcare and medical science. The book progresses logically from the history and fundamentals of photomedicine to di




Magnetic Nanoheterostructures


Book Description

This book contains most updated information on synthesis of magnetic nanohybrids, their physio-chemical properties, and key biological applications. It highlights the complexity of nanoheterostructures, especially magnetic metal oxides, ferrites and doped magnetic nanomaterials, and discusses their potential applications in the early detection, imaging and treatment of cancer. It also covers the toxicity and risk assessment of multifunctional nanomaterials. Providing an overview of magnetic nanoheterostructures, it appeals to a wide audience, from beginners and graduate-level students to experts in academia and industry.




Respiratory Endoscopy


Book Description

This book provides a detailed overview of the latest innovations in respiratory endoscopy, from both diagnostic and therapeutic perspectives; each chapter focuses on one disease and the techniques for early diagnosis as well as treatment. It comprehensively covers treatment and procedures, including simultaneous X-ray fluoroscopy and its use during bronchoscopic procedures. This fast-developing technology is essential for the medical management of non-malignant and malignant diseases of the chest, especially lung cancer. Respiratory Endoscopy describes the cooperation between all the members of the healthcare team, and as such is a valuable resource not only for medical staff, but also for radiological technicians and nursing staff who contribute significantly in the care of the patients undergoing these invasive procedures. By promoting teamwork and providing practical know-how, it will improve the success and safety of respiratory endoscopy procedures.




Imaging in Photodynamic Therapy


Book Description

This book covers the broad field of cellular, molecular, preclinical, and clinical imaging either associated with or combined with photodynamic therapy (PDT). It showcases how this approach is used clinically for cancer, infections, and diseases characterized by unwanted tissue such as atherosclerosis or blindness. Because the photosensitizers are also fluorescent, the book also addresses various imaging systems such as confocal microscopy and small animal imaging systems, and highlights how they have been used to follow and optimize treatment, and to answer important mechanistic questions. Chapters also discuss how imaging has made important contributions to clinical outcomes in skin, bladder, and brain cancers, as well as in the development of theranostic agents for detection and treatment of disease. This book provides a resource for physicians and research scientists in cell biology, microscopy, optics, molecular imaging, oncology, and drug discovery.




PET/CT and PET/MR in Melanoma and Sarcoma


Book Description

This is a comprehensive guide for patient preparation, image acquisition, and image interpretation for PET/CT and PET/MR, specifically relevant to melanoma and sarcoma. Imaging specialists and referring physicians are often not as intimately aware of the particulars of PET imaging in management of patients with melanoma and sarcoma and how it could affect their treatment. This book fills that gap by presenting comprehensive information on melanoma, sarcoma, and the role of PET imaging in their diagnosis and management. The book begins by covering the basics of imaging for practicing physicians and trainees. Expert authors then further cover the biological concepts of melanoma and sarcoma and how they relate to imaging, particularly PET, the oncologist’s perspective, and the surgeon’s perspective on imaging for both the imaging specialist and the referring physician. Chapters review topics such as: PET/CT and PET/MR images in melanoma and sarcoma from a systemic approach, false-positives, false-negatives, pitfalls, and molecular imaging beyond PET. Images are used extensively throughout to enhance understanding for the reader. This is an ideal guide for radiologists, nuclear medicine physicians, oncologists, surgeons, trainees and technologists.