Current Catalog


Book Description

First multi-year cumulation covers six years: 1965-70.




Chronic Liver Failure


Book Description

Chronic liver failure is a frequent condition in clinical practice that encompasses all manifestations of patients with end-stage liver diseases. Chronic liver failure is a multiorgan syndrome that affects the liver, kidneys, brain, heart, lungs, adrenal glands, and vascular, coagulation, and immune systems. Chronic Liver Failure: Mechanisms and Management covers for the first time all aspects of chronic liver failure in a single book, from pathogenesis to current management. Each chapter is written by a worldwide known expert in their area and all provide the latest state-of-the-art knowledge. This volume is specifically designed to provide answers to clinical questions to all doctors dealing with patients with liver diseases, not only clinical gastroenterologists and hepatologists, but also to internists, nephrologists, intensive care physicians, and transplant surgeons.




Gastrointestinal and Hepatic Immunology


Book Description

This 1994 volume summarizes basic scientific advances in the area of the gut immune system and the immune abnormalities relevant to gastrointestinal and liver disease.




Immunological Aspects of the Liver and Gastrointestinal Tract


Book Description

We have been privileged to start our academic careers at the begin ning of the decade in which the immunological roles and hypersensitivity diseases of the gastrointestinal tract and liver have been defined. In the early 1960s IgA was reported to be the main secretory immunoglobulin, immunoblasts were shown to home to the intestinal mucosa and certain serum autoantibodies were described in patients with chronic liver disease. Shortly thereafter IgE and Australia antigen were discovered. Parallel advances in clinical investigation, in particular closed biopsy techniques, facilitated correlation of morphological changes with im munological mechanisms in disease of the gastrointestinal tract and liver. Only 10 years later, the concepts of immunity and hypersensitivity are regularly applied to the pathogenesis, diagnosis, treatment and prog nosis of many chronic diseases in these organs. In designing this book we have attempted to integrate theorectical and clinical immunology as they pertain in 1975; our ultimate aim is aptly described by Brachet as quoted by Professor Paronetto (page 319). We would like to think that this review provides a basis for the next major advances in the fields of gastrointestinal and hepatic immunology. As we see it, the outstanding problem in both sites is how to produce protective immunity without hypersensitivity.







Immunological Aspects of Gastroenterology


Book Description

Diseases of the gastrointestinal tract are common. There is increasing appreciation of the importance of the immune system in the pathogenesis of a number of these diseases. This book covers basic aspects of innate and adaptive immunity in the gastrointestinal tract, oral tolerance, and cellular and molecular mechanisms of acute and chronic inflammation. Specific disease covered include bacterial infections, human immunodeficiency virus (HIV) infection, coeliac disease, and inflammatory bowel disease. Other topics include mucosal immunisation and intestinal transplantation immunology. The readership of this book includes clinicians, scientists, and students interested in the gastrointestinal tract.




Immunopharmacology of the Gastrointestinal System


Book Description

Diseases of the digestive system have a higher morbidity rate than any other group of disorder. There is a growing body of evidence that the immune system participates in the pathogenesis of a wide range of these diseases, including peptic ulcer disease and the gastropathy induced by nonsteroidal anti-inflammatory drugs (NSAIDS). For these reasons, efforts to develop novel therapies for digestive diseases are increasingly focused on the immune system. This volume reviews the immunopharmacology of the gastrointestinal tract at four distinct levels: Immunomodulation at a cellular level Cellular targers for immunomodulating drugs Specific classes of inflammatory mediators Utility and mechanisms of action of glucocorticoids in the treatment of diseases of the gastrointestinal tract.




Lewin, Weinstein and Riddell's Gastrointestinal Pathology and its Clinical Implications


Book Description

Lewin’s Gastrointestinal Pathology and Its Clinical Implications, Second Edition This comprehensive, two-volume resource highlights the practical aspects the pathology of biopsies and gross specimens, the clinical/pathological correlation, and differential diagnoses, and the ways in which these affect the management of patients with gastrointestinal disorders. The authors provide valuable insights on many important areas of gastrointestinal pathology, and openly address controversies within the specialty. This all-inclusive work stands alone in its illustrative quality and in its emphasis on the clinical implications of patient management as related to pathologic findings. The Second Edition has been completely revised to reflect two decades of advances in the field. The book’s focus on clinical/pathological correlations and differential diagnoses emphasizes their affect on patient management. Major revisions of the chapters on colitis and gastritis feature new approaches to treatment. Over 2100 full-color illustrations highlight pathologic features to sharpen diagnostic skills and guide treatment choices. NEW to the Second Edition... Completely revised content reflects two decades of advances in the field. Focus on clinical/pathological correlations and differential diagnoses emphasizes their affect on patient management Major revisions of the chapters on colitis and gastritis feature new approaches to treatment. Over 2100 full-color illustrations highlight pathologic features to sharpen diagnostic skills and guide treatment choices.