In Vitro Cultivation of Parasitic Helminths (1990)


Book Description

A critical account of the available techniques for the in vitro cultivation of parasitic helminths (Trematoda, Cestoda, Nematoda, and Acanthocephala), concentrating on those which have been reasonably successful and can be used for teaching or research purposes. In addition to describing basic techn




Chemotherapeutic Targets in Parasites


Book Description

Parasitic infections are the most prevalent of human diseases, and researchers continue to face the challenge of designing drugs to successfully counteract them. Chemotherapeutic Targets in Parasites analyzes the critical metabolic reactions and structural features essential for parasite survival, and advocates the latest molecular strategies with which to identify effective antiparasitic agents. An introduction to the early development of parasite chemotherapy is followed by an overview of biophysical techniques and genomic and proteomic analysis. Several chapters are devoted to specific types of chemotherapeutic agents and their targets in malaria, trypanosomes, leishmania and amitochondrial protists. Chapters on helminths include metabolic, neuromuscular, microtubular and tegumental targets. Emphasized throughout is the design of more selective and less toxic drugs than in the past. This book will be especially relevant to medical and clinical researchers and to graduate students in parasitology, pharmacology, medicine, microbiology, and biochemistry.




Parasiticide Screening


Book Description

Parasiticide Discovery: In Vitro and In Vivo Tests with Relevant Parasite Rearing and Host Infection/Infestation Methods, Volume One presents valuable screening methods that have led to the discovery of the majority of parasiticides commercialized in the animal health industry. As much of the knowledge of parasiticide discovery methods is being lost in the animal health industry as seasoned parasitologists retire, this book serves to preserve valuable methods that have led to the discovery of the majority of parasiticides commercialized in animal health, also giving insights into the in vitro and in vivo methods used to identify the parasiticide activity of compounds. - Addresses current issues of resistance, along with combination uses for resistant parasites - Presents useful, authoritative information (chemical, pharmaceutical, clinical, etc.) for the pyrantel family of compounds - Includes a discussion on screening methods in combination therapies - Provides cutting-edge material for an evolving area of scientific discussion - Includes in vitro and in vivo screens and parasite maintenance and culture methods




Advances in Trematode Biology


Book Description

Trematodology - the study of a class of medically important parasitic, flat-bodied worms - has made significant advances over the past ten years. The tremendous amount of information accumulated from research discoveries and technical developments related to trematode biology makes this book a timely and necessary part of the literature. Advances in Trematode Biology presents a thorough treatment of modern trematodology, including principles and practices. With coverage of background material as well as modern methods, Advances in Trematode Biology updates researchers, practitioners, and students with new information in immunology, biochemistry, physiology, and molecular biology. Advances in Trematode Biology includes practical information on parasitological techniques, emphasizing species of medical and veterinary importance - a key reference for parasitologists, biologists, medical, and veterinary personnel. The excellent presentation of material, including well-organized tables and chapters, make Advances in Trematode Biology easy to use both as a textbook and as a reference.




Advances in Parasitology


Book Description

From the Reviews of Previous Volumes"In reviewing this volume as a whole, one is struck by the quality and scholarship of the various chapters and the obviously efficient editing."-PARASITOLOGY"The policy of the editors of Advances in Parasitology to include reviews from any aspect of parasitology and the high standard of individual papers have resulted in this series of volumes becoming an indispensable source for students, teachers, and research workers."-ANNALS OF TROPICAL MEDICINE AND PARASITOLOGY




Revival: In Vitro Cultivation of Parasitic Helminths (1990)


Book Description

A critical account of the available techniques for the in vitro cultivation of parasitic helminths (Trematoda, Cestoda, Nematoda, and Acanthocephala), concentrating on those which have been reasonably successful and can be used for teaching or research purposes. In addition to describing basic techn




Laboratory Models for Foodborne Infections


Book Description

Resulting from ingestion of inappropriately prepared or stored foods containing pathogenic viruses, bacteria, fungi and parasites, foodborne infections have become a significant source of human morbidity and mortality worldwide in recent decades. This may be largely attributable to the remarkable popularity of convenient, ready-to-eat food products, the dramatic expansion of international food trades, and the continuing growth of immuno-suppressed population groups. Although anti-microbial treatments have played a crucial part in the control of foodborne infections in the past, the emergence and spread of anti-microbial resistance render the existing treatments ineffective. Additionally, our limited understanding of the molecular mechanisms of foodborne infections has thwarted our efforts in the development of efficacious vaccines for foodborne pathogens. Given the obvious benefits of laboratory models in foodborne disease research, a great number of experiments have been conducted toward the elucidation of host-pathogen interactions in and pathogenic mechanisms of foodborne infections. Forming part of the Food Microbiology series, Laboratory Models for Foodborne Infections presents a state-of-the-art review of laboratory models that have proven valuable in deciphering the life cycle, epidemiology, immunobiology, and other key aspects of foodborne pathogens. Written by scientists with respective expertise in foodborne pathogen research, each chapter includes a contemporary summary of a particular foodborne viral, bacterial, fungal, or parasitic infection in relation to its life cycle, epidemiology, clinical features, pathogenesis, host-pathogen interactions, and other related aspects. Besides providing a trustworthy source of information for undergraduates and postgraduates in food microbiology, Laboratory Models for Foodborne Infections offers an invaluable guide for scientists and food microbiologists with interest in exploiting laboratory models for detailed study of foodborne infections.







Guide to Foodborne Pathogens


Book Description

An expert survey of foodborne pathogens, illnesses, and control methods This volume offers broad and accessible coverage of the pathogens-bacteria, viruses, and parasites-most commonly responsible for foodborne illness. It discusses the nature of illnesses; the epidemiology of pathogens; and current detection, prevention, and control methods. It also features chapters on the globalization of the food supply, seafood toxins, and other miscellaneous agents. Twenty-one chapters, by experts from around the world, cover the most dangerous illnesses and foodborne pathogens currently threatening world populations. Topics include: * Arcobacter/Helicobacter * Aspergillus * Bacillus cereus * Campylobacter * Clostidium perfringens * Clostridium botulinum * Escherichia coli * Fusarium * Listeria * Salmonella * Shigella * Staphylococcus aureus * Vibrio * Yersinia enterocolitica Guide to Foodborne Pathogens offers up-to-date analysis of the growing body of scientific information on both established and new and emerging pathogens. It provides concise coverage that serves the needs of scientists and food professionals who lack a specialized background in foodborne illness but want to stay informed on this vital health issue.




Echinostomes as Experimental Models for Biological Research


Book Description

Echinostomes are ubiquitous intestinal flatworm parasites of vertebrates and are of importance in human and veterinary medicine and wildlife diseases. Echinostomes can be maintained easily and inexpensively in the laboratory and provide good models for biological research ranging from the molecular to the organismal. Considerable but scattered literature has been published on the subject of echinostomes and a synthesis of this wide range of topics has now been achieved with the publication of this book, which presents a wide range of topics in experimental biology related to the use of echinostomes as laboratory models. It will have a special appeal to advanced undergraduates and graduate students in parasitology and should also appeal to professional parasitologists, physicians, veterinarians, wildlife disease biologists, and any biomedical scientists interested in new model systems for studies in experimental biology.