Author : Kenneth Söderhäll
Publisher : Springer Science & Business Media
Page : 338 pages
File Size : 16,68 MB
Release : 2011-06-28
Category : Medical
ISBN : 1441980598
It can be seen that the insects are the still attracting most research and researchers. However, an increasing interest is emerging to study new invertebrate groups, especially those where the genome is known. Even though Drosophila has been and still is an excellent model for immune studies, it is now clear that there are great differences between immune responses in Drosophila and that of several other invertebrates, which indeed calls for more research on other invertebrates
Author : National Institutes of Health (U.S.)
Publisher :
Page : 392 pages
File Size : 39,7 MB
Release : 1975
Category : Medical
ISBN :
Author : Alain Beschin
Publisher : Springer
Page : 184 pages
File Size : 44,6 MB
Release : 2012-11-22
Category : Science
ISBN : 9783642622366
Based on the assumption that invertebrates as well as vertebrates possess factors regulating hematopoiesis, response to infection or wounding, studies dealing with the evolution of immunity have focused on the isolation and characterization of putative cytokine-related molecules from invertebrates. Until recently, most of our knowledge of cytokine- and cytokine receptor-like molecules in invertebrates has relied on functional assays and similarities at the physicochemical level. As such, a phylogenetic relationship between invertebrate cytokine-like molecules and invertebrate counterparts could not be convincingly demonstrated. In the present book, recent studies demonstrating cytokine-like activities and related signaling pathways in invertebrates are critically reviewed, focusing on findings from molecular biology and taking advantage of the completion of the genome from the fly Drosophila and the worm Caenorhabditis elegans.
Author :
Publisher :
Page : 0 pages
File Size : 13,47 MB
Release : 2002
Category : Cells
ISBN : 9780815332183
Author : Karl Maramorosch
Publisher : Elsevier
Page : 378 pages
File Size : 47,1 MB
Release : 2012-12-02
Category : Science
ISBN : 0323153267
Invertebrate Immunity: Mechanisms of Invertebrate Vector-Parasite Relations consists of chapters presented at a workshop on invertebrate defense mechanisms, sponsored by the National Institutes of Health and held in Bethesda, Maryland, on April 17 and 18, 1974. Organized into four parts, having a total of 24 chapters, this book first discusses the barrier imposed by the gut of invertebrates to invading parasites. It then centers on the role of invertebrate hemocytes and other phagocytic cells in immunity, as well as the humoral defense mechanisms of these organisms. Other topics discussed include parasite encapsulation in insects, role of melanin in host-parasite interaction, and use of host hormones by insect parasites to make the host environment favorable for their growth and development. This book will be essential for those interested in comparative immunology and in invertebrate immune responses. It will be of special interest to entomologists, protozoologists, physicians, veterinarians, ecologists, pathologists, research workers, science teachers, and graduate students.
Author : Loriano Ballarin
Publisher : Academic Press
Page : 326 pages
File Size : 24,29 MB
Release : 2016-04-08
Category : Medical
ISBN : 0128032537
Lessons in Immunity: From Single-cell Organisms to Mammals stems from the activity of the Italian Association of Developmental and Comparative Immunobiology (IADCI), represented by the editors. This book is presented as a series of short overviews that report on the current state of various relevant fields of immunobiology from an evolutionary perspective. The overviews are written by authors directly involved in the research, and most are members of the IADCI or have otherwise been involved in the related research for their respective overview. This publication offers scientists and teachers an easy and updated reference tool. - Provides simple and updated reviews on the immunobiology of a wide spectrum of organisms, considered in an evolutionary context - Focuses on both cells and humoral components of a variety of non-classical model organisms - Offers in a single volume many contributions which can help with understanding the evolution of immune responses and the main adaptations in animal phyla - Presents a valuable holistic cross-sectional approach for teaching immunology and its applications
Author : L. Du Pasquier
Publisher : Springer Science & Business Media
Page : 324 pages
File Size : 41,64 MB
Release : 2012-12-06
Category : Medical
ISBN : 3642596746
The comparative approach to immunology can be traced to the era of Pasteur and Metchnikov in which observations regarding foreign recognition in invertebrates was a factor in the develop ment of the principal concepts that created the foundation of what now is the broad field of immunology. With each major experimental and conceptual breakthrough, the classical, albeit essential, question has been asked "are the immune systems of phylogenetically primitive vertebrates and invertebrates similar to that of mammals?" Somewhat surprisingly for the jawed verte brates, the general answer has been a qualified form of "yes", whereas for agnathans and invertebrate phyla it has been "no" so far. The apparent abruptness in the appearance of the immune system of vertebrates is linked to the introduction of the somatic generation of the diversity of its antigen specific receptors. Therefore the questions regarding the origin and evolution of the specific immune system revolve around this phenomenon. With respect to the origin of the system (aside from the or igin of the rearranging machinery itself, the study of which is still in its infancy) one can ask questions about the cellular and mo lecular contexts in which the mechanism was introduced.
Author : Lorand Bertok
Publisher : Elsevier
Page : 397 pages
File Size : 31,41 MB
Release : 2005-04-11
Category : Medical
ISBN : 0080460461
"Natural Immunity" is a broadly-based account of the activities of the evolutionarily conserved molecules, cells and processes of the natural immune system. This encompasses the early host protection against microbes (bacteria and viruses) and tumours, prior to the generation of the adaptive immune response, diverse major current pathologies including inflammatory and autoimmune diseases, and key roles in essential physiological processes such as reproduction and wound healing. - The first comprehensive book on natural immunity - Reviews new topics, effects of behaviour, aging, and exercise, and diet on natural immunity - Highlights the physiological role of natural immunity - Focuses on the relationship of the neuroendocrine system with natural immunity - Brings together the diversity and complexity of natural immune system activity
Author : J.M. Arcier
Publisher : Springer Science & Business Media
Page : 237 pages
File Size : 41,3 MB
Release : 2012-12-06
Category : Science
ISBN : 3642707688
Author : Yves Carton
Publisher : ISTE Press - Elsevier
Page : 324 pages
File Size : 23,14 MB
Release : 2019-11-15
Category : Medical
ISBN : 1785483080
Innate immunity is a new branch of immunology, confirmed by three Nobel Prize winners in 2011. It is the first line of defense against pathogens and is in a way the preliminary step of adaptive immunity which occurs later, and only present in vertebrates. This book examines the way in which innate immunity was discovered in invertebrates. As a starting point, it looks at the work of Louis Pasteur on silkworm disease and the findings of Ilya Metchnikov, discoverer of phagocytosis. It also investigates André Paillot, who in 1920 demonstrated the existence of humoral immunity in insects, unrelated to the type of immunity that was initially thought to be present in all vertebrates. Finally, Innate Immunity shows how the group directed by Jules Hoffmann found strong similarities between the innate immunity response of insects and mammals. The discovery of a receptor protein in Drosophila, which is also found in humans, was what led to Jules Hoffmann being awarded the Nobel Prize in 2011.
