ISCOMS - Book of Abstracts
Author :
Publisher : ISCOMS
Page : 330 pages
File Size : 44,27 MB
Release : 2005
Category :
ISBN : 9036722969
Chemical Abstracts
Author :
Publisher :
Page : 2540 pages
File Size : 39,38 MB
Release : 2002
Category : Chemistry
ISBN :
Book Description
Immunomic Discovery of Adjuvants and Candidate Subunit Vaccines
Author : Darren R. Flower
Publisher : Springer Science & Business Media
Page : 316 pages
File Size : 31,92 MB
Release : 2012-12-09
Category : Medical
ISBN : 1461450705
Book Description
This volume will address an important emergent area within the field of immunomics: the discovery of antigens and adjuvants within the context of reverse vaccinology. Conventional approaches to vaccine design and development requires pathogens to be cultivated in the laboratory and the immunogenic molecules within them to be identifiable. Conventional vaccinology is no longer universally successful, particularly for recalcitrant pathogens. By using genomic information we can study vaccine development in silico: 'reverse vaccinology', can identify candidate subunits vaccines by identifying antigenic proteins and by using equally rational approaches to identify novel immune response-enhancing adjuvants.
Subunit Vaccine Delivery
Author : Camilla Foged
Publisher : Springer
Page : 433 pages
File Size : 25,7 MB
Release : 2014-11-22
Category : Medical
ISBN : 1493914170
Book Description
This comprehensive volume compiles the concepts essential for the understanding of the pharmaceutical science and technology associated with the delivery of subunit vaccines. Twenty-one chapters are divided into four main parts: (I) Background; (2) Delivery Systems for Subunit Vaccines; (3) Delivery Routes, Devices and Dosage Forms; and (4) Pharmaceutical Analysis and Quality Control of Vaccines. Part one provide a basic background with respect to immunology and general vaccine classification. In part two, it presents representative types of vaccine delivery systems individually with focus on the physicochemical properties of the systems and their significance for the immune response they stimulate. These delivery systems include aluminum adjuvants, emulsions, liposomes, bilosomes, cubosomes/hexosomes, ISCOMs, virus-like particles, polymeric nano- and microparticles, gels, implants and cell-based delivery systems. Following these chapters, part three addresses the challenges associated with vaccine delivery via specific routes of administration—in particular subcutaneous, intramuscular, oral, nasal, pulmonary, transdermal and vaginal administration. Furthermore, the specific administration routes are discussed in combination with device technologies relevant for the respective routes as well as dosage forms appropriate for the device technology. Finally, the fourth part concerns pharmaceutical analysis and quality control of subunit vaccines.
Nanotechnology Based Approaches for Tuberculosis Treatment
Author : Prashant Kesharwani
Publisher : Academic Press
Page : 286 pages
File Size : 43,39 MB
Release : 2020-06-10
Category : Medical
ISBN : 0128226110
Book Description
Nanotechnology Based Approaches for Tuberculosis Treatment discusses multiple nanotechnology-based approaches that may help overcome persisting limitations of conventional and traditional treatments. The book summarizes the types of nano drugs, their synthesis, formulation, characterization and applications, along with the most important administration routes. It also explores recent advances and achievements regarding therapeutic efficacy and provides possible future applications in this field. It will be a useful resource for investigators, pharmaceutical researchers, innovators and scientists working on technology advancements in the areas of targeted therapies, nano scale imaging systems, and diagnostic modalities in tuberculosis. - Addresses the gap between nanomedicine late discovery and early development of tuberculosis therapeutics - Explores tuberculosis nanomedicine standardization and characterization with newly developed treatment, diagnostic and treatment monitoring modalities - Covers the field thoroughly, from the pathogenesis of tuberculosis and multi-drug resistant mycobacterium tuberculosis, to treatment approaches using nanotechnology and different nanocarriers
Immunopotentiators in Modern Vaccines
Author : Virgil Schijns
Publisher : Elsevier
Page : 396 pages
File Size : 40,90 MB
Release : 2005-12-19
Category : Medical
ISBN : 0080457215
Book Description
Immunopotentiators in Modern Vaccines provides an in-depth insight and overview of a number of most promising immunopotentiators in modern vaccines. In contrast to existing books on the subject it provides recent data on the critical mechanisms governing the activity of vaccine adjuvants and delivery systems. Knowledge of immunological pathways and scenarios of the cells and molecules involved is described and depicted in comprehensive illustrations. - Contributions from leading international authorities in the field - Well-illustrated, informative figures present the interactions between immunopotentiators and the host immune system - Each chapter lists advantages and potential hurdles for achieving a practical application for the specific immunopentiator
Virally Infected Cells
Author : J. Robin Harris
Publisher : Springer Science & Business Media
Page : 490 pages
File Size : 30,48 MB
Release : 1989-07-31
Category : Science
ISBN : 9780306431388
Book Description
Cellular virology has made tremendous advances in the past decade due to the availability and application of new immunological techniques together with the vast range of biochemical techniques and the continued impact of transmission electron microscopy. The chapters contained in this volume provide significant coverage of the subject of cellular virology as a whole. Considerable overall emphasis is placed upon the membrane biochemistry of viral proteins and glycoproteins within the infected cell. In the opening chapter Edouard Kurstak and his colleagues provide a useful survey on the detection of viral antigens and antibodies by immunoassays. This chapter, with its emphasis on the important role of immunology in present-day virology, sets the scene for the volume. Following this is an exciting presentation from Stefan Hoglund and his colleagues on ISCOMs and immunostimulation with viral antigens. This unique approach is already proving to be of value, particularly in animal virology. A somewhat pharmacological diversion appears in Chapter 3, by Kazukiyo Onodera and his colleagues, in which the biological activity of the damavaricin C derivatives is discussed. This chapter provides a link between the biochemical and the chemotherapeutic approach in cellular virology. Yet another specialist area is covered in Chapter 4 by Otto Schmidt and hnke Schuchmann-Feddersen, who discuss the role of virus-like particles in para site-host interactions of insects. Contributing a strong biomedical emphasis to the volume is the provocative chapter by Abraham Karpas on human leukemia and retroviruses.
Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases E-Book
Author : John E. Bennett
Publisher : Elsevier Health Sciences
Page : 5094 pages
File Size : 30,73 MB
Release : 2014-09-02
Category : Medical
ISBN : 0323263739
Book Description
After thirty five years, Mandell, Douglas, and Bennett’s Principles and Practice of Infectious Diseases, 8th Edition is still the reference of choice for comprehensive, global guidance on diagnosing and treating the most challenging infectious diseases. Drs. John E. Bennett and Raphael Dolin along with new editorial team member Dr. Martin Blaser have meticulously updated this latest edition to save you time and to ensure you have the latest clinical and scientific knowledge at your fingertips. With new chapters, expanded and updated coverage, increased worldwide perspectives, and many new contributors, Mandell, Douglas, and Bennett’s Principles and Practice of Infectious Diseases, 8th Edition helps you identify and treat whatever infectious disease you see. Get the answers to any questions you have with more in-depth coverage of epidemiology, etiology, pathology, microbiology, immunology, and treatment of infectious agents than you’ll find in any other ID resource. Apply the latest knowledge with updated diagnoses and treatments for currently recognized and newly emerging infectious diseases, such as those caused by avian and swine influenza viruses. Put the latest knowledge to work in your practice with new or completely revised chapters on Influenza (new pandemic strains); New Middle East Respiratory Syndrome (MERS) Virus; Probiotics; Antibiotics for resistant bacteria; Antifungal drugs; New Antivirals for hepatitis B and C; Clostridium difficile treatment; Sepsis; Advances in HIV prevention and treatment; Viral gastroenteritis; Lyme Disease; Helicobacter pylori; Malaria; Infections in immunocompromised hosts; Immunization (new vaccines and new recommendations); and Microbiome. Benefit from fresh perspectives and expanded global insights from an expanded team of American and International contributors. Martin Blaser, MD, a leading expert and Muriel G. and George W. Singer Professional of Translational Medicine at New York University School of Medicine, joins veteran PPID editors John E. Bennett, MD, and Raphael Dolin, MD to continue a legacy of excellence. Find and grasp the information you need easily and rapidly with newly added chapter summaries.
Better Posters
Author : Zen Faulkes
Publisher : Pelagic Publishing Ltd
Page : 429 pages
File Size : 42,6 MB
Release : 2021-05-24
Category : Science
ISBN : 1784272361
Book Description
Better posters mean better research. Distilling over a decade of experience from the popular Better Posters blog, Zen Faulkes will help you create a clear and informative conference poster that delivers maximum impact. Academics have used posters to share research for more than five decades, and tens of thousands of posters are presented at conferences every year. Despite the popularity of the format, no in-depth guide has been available on how to create and deliver compelling conference posters. From over-long titles, tiny text and swarms of logos, to bad font choices, chaotic colour schemes and blurry images – it’s easy to leave viewers confused about your poster’s message. The solution is Better Posters: a comprehensive guide to everything you need to know – from writing a title and submitting an abstract, to designing the poster and finally presenting it in the poster session. Your conference poster will be one of your first research outputs, and the poster session is your first introduction to a professional community. Making a great poster develops the skills to create publications, reports, outreach and teaching materials throughout your career. This book also has material for conference organizers on how to make a better poster session for their attendees.
The Threat of Pandemic Influenza
Author : Institute of Medicine
Publisher : National Academies Press
Page : 431 pages
File Size : 29,58 MB
Release : 2005-04-09
Category : Medical
ISBN : 0309095042
Book Description
Public health officials and organizations around the world remain on high alert because of increasing concerns about the prospect of an influenza pandemic, which many experts believe to be inevitable. Moreover, recent problems with the availability and strain-specificity of vaccine for annual flu epidemics in some countries and the rise of pandemic strains of avian flu in disparate geographic regions have alarmed experts about the world's ability to prevent or contain a human pandemic. The workshop summary, The Threat of Pandemic Influenza: Are We Ready? addresses these urgent concerns. The report describes what steps the United States and other countries have taken thus far to prepare for the next outbreak of "killer flu." It also looks at gaps in readiness, including hospitals' inability to absorb a surge of patients and many nations' incapacity to monitor and detect flu outbreaks. The report points to the need for international agreements to share flu vaccine and antiviral stockpiles to ensure that the 88 percent of nations that cannot manufacture or stockpile these products have access to them. It chronicles the toll of the H5N1 strain of avian flu currently circulating among poultry in many parts of Asia, which now accounts for the culling of millions of birds and the death of at least 50 persons. And it compares the costs of preparations with the costs of illness and death that could arise during an outbreak.
