Holding Hands with Bacteria


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This biographical brief outlines the remarkable life and career of British biochemist, Marjory Stephenson (1885-1948). In nine concise chapters, Štrbáňová describes Stephenson's scientific accomplishments and sets these against the socio-political challenges of the time. Stephenson played an important role in the development of biochemistry and molecular biology. She was one of the first scientists to use microorganisms as models for research into cellular biochemical processes and their regulation. Later she went on to coin the term chemical microbiology, which was communicated in her monograph and textbook "Bacterial Metabolism" (1930-1949). Stephenson also actively participated in the establishment of the institutionalized interdisciplinary field of general microbiology which integrated research into diverse forms of microorganisms at various levels of organization. Alongside these scientific achievements, Štrbáňová outlines Stephenson's constant battle with practices of undeclared discrimination, her important role as one of the first women science managers and organizers, and her influential position within the scientific community. A scientist of great merit and a role model to women scientists of all disciplines, the life of Marjory Stephenson is of interest to biochemists, molecular biologists, historians of the chemical and biological sciences, and women scientists of all generations.




Albert Jan Kluyver


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I Wish I'd Made You Angry Earlier


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This collection of essays from Nobel Laureate Max Perutz explores a wide range of scientific and personal topics with insight and lucidity. It includes lively anecdotes about key figures in 20th-century science.




The Private Science of Louis Pasteur


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In The Private Science of Louis Pasteur, Gerald Geison has written a controversial biography that finally penetrates the secrecy that has surrounded much of this legendary scientist's laboratory work. Geison uses Pasteur's laboratory notebooks, made available only recently, and his published papers to present a rich and full account of some of the most famous episodes in the history of science and their darker sides--for example, Pasteur's rush to develop the rabies vaccine and the human risks his haste entailed. The discrepancies between the public record and the "private science" of Louis Pasteur tell us as much about the man as they do about the highly competitive and political world he learned to master. Although experimental ingenuity served Pasteur well, he also owed much of his success to the polemical virtuosity and political savvy that won him unprecedented financial support from the French state during the late nineteenth century. But a close look at his greatest achievements raises ethical issues. In the case of Pasteur's widely publicized anthrax vaccine, Geison reveals its initial defects and how Pasteur, in order to avoid embarrassment, secretly incorporated a rival colleague's findings to make his version of the vaccine work. Pasteur's premature decision to apply his rabies treatment to his first animal-bite victims raises even deeper questions and must be understood not only in terms of the ethics of human experimentation and scientific method, but also in light of Pasteur's shift from a biological theory of immunity to a chemical theory--similar to ones he had often disparaged when advanced by his competitors. Through his vivid reconstruction of the professional rivalries as well as the national adulation that surrounded Pasteur, Geison places him in his wider cultural context. In giving Pasteur the close scrutiny his fame and achievements deserve, Geison's book offers compelling reading for anyone interested in the social and ethical dimensions of science. Originally published in 1995. The Princeton Legacy Library uses the latest print-on-demand technology to again make available previously out-of-print books from the distinguished backlist of Princeton University Press. These editions preserve the original texts of these important books while presenting them in durable paperback and hardcover editions. The goal of the Princeton Legacy Library is to vastly increase access to the rich scholarly heritage found in the thousands of books published by Princeton University Press since its founding in 1905.




Bacterial Physiology


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Bacterial Physiology focuses on the physiology and chemistry of microorganisms and the value of bacterial physiology in the other fields of biology. The selection first underscores the chemistry and structure of bacterial cells, including the chemical composition of cells, direct and indirect methods of cytology, vegetative multiplication, spores of bacteria, and cell structure. The text then elaborates on inheritance, variation, and adaptation and growth of bacteria. The publication reviews the physical and chemical factors affecting growth and death. Topics include hydrogen ion concentration and osmotic pressure; surface and other forces determining the distribution of bacteria in their environment; dynamics of disinfection and bacteriostasis; bacterial resistance; and types of antibacterial agents. The text also ponders on the anaerobic dissimilation of carbohydrates, bacterial oxidations, and autotrophic assimilation of carbon dioxide. The selection is a dependable reference for readers interested in bacterial physiology.




J. D. Bernal


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J.D. Bernal, widely known as Sage since his undergraduate days at Cambridge, was a visionary scientist who was the first to see that the new subject of X-ray crystallography could be applied to the study of life. His pioneering work at Cambridge in the 1930s laid the foundation of molecular biology. He was one of the most influential and brilliant scientists of his time, inspiring many subsequent Nobel laureates. Bernal's restless energy and legendary intellect took him far beyond science. An astonishing polymath and a fervent Marxist, he was one of the central figures in a cosmopolitan intelligentsia in an age of extremes. The story of Bernal's life reflects the extraordinary political and intellectual climate in which he lived. He was witness to (and often involved in) some of the great events of the 20th century: the Easter Rebellion, schooldays in the Great War, the anti-fascist movement, the Second World War, pacifist causes and nuclear disarmament during the Cold War. He was a pioneer of Operational Research during WW2 and made the first objective analyses of the effects of bombing on cities. As this biography shows, he played a crucial role in planning the D-Day landings, arriving secretly on the Normandy beaches himself a day later. After the war, he became an international ambassador for Marxism, science, and peace, and was one of the few men familiar with Downing Street, the White House and the Kremlin. Brown's biography sets out a life richly and fully lived. Nearly every important British scientist of the mid-third of the 20th century appears in its pages, along with artists (Picasso, Hepworth), writers (Leonard and Virginia Woolf, Aldous Huxley, Pablo Neruda) and statesmen (Churchill, Khrushchev, Mao, and Nehru). This compelling account draws on unprecedented access to Bernal's papers and war reports to piece together a dazzling image of Bernal: his Irish Catholic childhood, his Cambridge years, his research, his dedication to science, his intellectual brilliance, his blind, unswerving commitment to Marxism, his unorthodox Bohemian love life. But above all, the Bernal who emerges from this often critical account is a man not only of remarkable mental powers but of great warmth, kindness, and humanity.




Proteins and Nucleic Acids


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Milestones in Microbiology


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