The Patagonian Hare


Book Description

The unforgettable memoir of 70 years of contemporary and personal history from the great French filmmaker, journalist and intellectual Claude Lanzmann Born to a Jewish family in Paris, 1925, Lanzmann's first encounter with radicalism was as part of the Resistance during the Nazi occupation. He and his father were soldiers of the underground until the end of the war, smuggling arms and making raids on the German army. After the liberation of France, he studied philosophy at the Sorbonne, making money as a student in surprising ways (by dressing as a priest and collecting donations, and stealing philosophy books from bookshops). It was in Paris however, that he met Jean-Paul Sartre and Simone de Beauvoir. It was a life-changing meeting. The young man began an affair with the older de Beauvoir that would last for seven years. He became the editor of Sartre's political-literary journal, Les Temps Modernes—a position which he holds to this day—and came to know the most important literary and philosophical figures of postwar France. And all this before he was 30 years old. Written in precise, rich prose of rare beauty, organized—like human recollection itself—in interconnected fragments that eschew conventional chronology, and describing in detail the making of his seminal film Shoah, The Patagonian Hare becomes a work of art, more significant, more ambitious than mere memoir. In it, Lanzmann has created a love song to life balanced by the eye of a true auteur.




Kiss of Death


Book Description

Documents the life stories of death-row prisoners and the author's experiences as a pro bono attorney on Texas death penalty cases to present arguments for the abolishment of state-sanctioned executions.




Cystogenesis


Book Description

Autosomal Dominant Polycystic Kidney Disease (ADPKD) is a highly prevalent hereditary renal disorder in which fluid-filled cysts are appeared in both kidneys. Main causative genes of ADPKD are PKD1 and PKD2, encoding for polycystin-1 (PC1) and polycystin-2 (PC2) respectively. Those proteins are localized on primary cilia and function as mechanosensor in response to the fluid flow, translating mechanistic stimuli into calcium signaling. With mutations either of PKD1 or PKD2, hyper-activated renal tubular epithelial cell proliferation is observed, followed by disrupted calcium homeostasis and aberrant intracellular cyclic AMP (cAMP) accumulation. Increased cell proliferation with fluid secretion leads to the development of thousands of epithelial-lined, fluid-filled cysts in kidneys. It is also accompanied by interstitial inflammation, fibrosis, and finally reaching end-stage renal disease (ESRD). In human ADPKD, the age at which renal failure typically occurs is later in life, however no specific targeted medications are available to cure ADPKD. Recently, potential therapeutic targets or surrogate diagnostic biomarkers for ADPKD are proposed with the advances in the understanding of ADPKD pathogenesis, and some of them were attempted for clinical trials. Herein, we will summarize genetic and epi-genetic molecular mechanisms in ADPKD progression, and overview the currently available biomarkers or potential therapeutic reagents suggested.




The Construction of Testimony


Book Description

Groundbreaking analyses of the vast archive of newly digitized and released outtakes from Lanzmann's masterwork.




Early Identification of Risk Factors for Parental Abduction


Book Description

The Office of Juvenile Justice and Delinquency Prevention of the U.S. Department of Justice presents the full text of a bulletin entitled "Early Identification of Risk Factors for Parental Abduction," published in March 2001. The bulletin discusses the risk factors associated with parental kidnapping and strategies that may be used to intervene with families at greatest risk. The bulletin highlights research findings related to the risk factors and the effectiveness of the legal system's response to family abduction.




The Science and Applications of Microbial Genomics


Book Description

Over the past several decades, new scientific tools and approaches for detecting microbial species have dramatically enhanced our appreciation of the diversity and abundance of the microbiota and its dynamic interactions with the environments within which these microorganisms reside. The first bacterial genome was sequenced in 1995 and took more than 13 months of work to complete. Today, a microorganism's entire genome can be sequenced in a few days. Much as our view of the cosmos was forever altered in the 17th century with the invention of the telescope, these genomic technologies, and the observations derived from them, have fundamentally transformed our appreciation of the microbial world around us. On June 12 and 13, 2012, the Institute of Medicine's (IOM's) Forum on Microbial Threats convened a public workshop in Washington, DC, to discuss the scientific tools and approaches being used for detecting and characterizing microbial species, and the roles of microbial genomics and metagenomics to better understand the culturable and unculturable microbial world around us. Through invited presentations and discussions, participants examined the use of microbial genomics to explore the diversity, evolution, and adaptation of microorganisms in a wide variety of environments; the molecular mechanisms of disease emergence and epidemiology; and the ways that genomic technologies are being applied to disease outbreak trace back and microbial surveillance. Points that were emphasized by many participants included the need to develop robust standardized sampling protocols, the importance of having the appropriate metadata, data analysis and data management challenges, and information sharing in real time. The Science and Applications of Microbial Genomics summarizes this workshop.




Appliance Labeling


Book Description







Developing the Curriculum


Book Description

Previous editions have Peter Oliva as only author.




Hijacked Justice


Book Description

What is the appropriate political response to mass atrocity? In Hijacked Justice, Jelena Subotic traces the design, implementation, and political outcomes of institutions established to deal with the legacies of violence in the aftermath of the Yugoslav wars. She finds that international efforts to establish accountability for war crimes in the former Yugoslavia have been used to pursue very different local political goals.Responding to international pressures, Serbia, Croatia, and Bosnia have implemented various mechanisms of "transitional justice"—the systematic addressing of past crimes after conflicts end. Transitional justice in the three countries, however, was guided by ulterior political motives: to get rid of domestic political opponents, to obtain international financial aid, or to gain admission to the European Union. Subotic argues that when transitional justice becomes "hijacked" for such local political strategies, it fosters domestic backlash, deepens political instability, and even creates alternative, politicized versions of history. That war crimes trials (such as those in The Hague) and truth commissions (as in South Africa) are necessary and desirable has become a staple belief among those concerned with reconstructing societies after conflict. States are now expected to deal with their violent legacies in an institutional setting rather than through blanket amnesty or victor's justice. This new expectation, however, has produced paradoxical results. In order to avoid the pitfalls of hijacked justice, Subotic argues, the international community should focus on broader and deeper social transformation of postconflict societies, instead on emphasizing only arrests of war crimes suspects.