Kingdoms of Ahn Daowen


Book Description

Espyrea is but one island kingdom in a world rich with magic and adventure, monsters and elves, dragons and prophecies. For Conall, Jaehan, and their friends, the isle is home, and dire times have befallen her enchanted shores. The Keer Ohg--a clockwork foe so loathsome even the moon and the sun would see them dead--have conjured a terrible storm to mantle the entire kingdom.Unless the heroes can stop the Clockwork King and his wicked minions, Espyrea will surely fall. It will be the first kingdom of many, before all of Ahn Daowen is swathed in endless storms.Cover art by Greg Spalenka




Blood Charged


Book Description

Sardelle Terushan, sorceress and healer, should be lying low. Magic is forbidden in Iskandia, and magic users are drowned, shot, or otherwise slain. The problem? She's fallen in love with ace fighter pilot and national hero, Colonel Ridge Zirkander, a man whom everybody notices, including the king. It's not long before Sardelle has spies dogging her steps and people trying to blow her up. Worse, her presence is jeopardizing Ridge's career. If she can't find a solution to the nation's centuries-old hatred of magic, the only way to protect Ridge-and herself-may be to leave. Ridge Zirkander isn't used to worrying about more than shooting down Cofah airships and keeping the officers in his squadron alive, but his world has gotten more complicated since giving his heart to Sardelle. It's difficult to keep people from noticing a mysterious and enigmatic woman, not to mention her chatty sentient sword. He's been passing her off as an archaeologist to his fellow pilots, but when the king calls him in to a private meeting, Ridge fears his secret has been discovered. But the king-and the rest of the country-has a greater problem. Cofah military scientists have acquired something that shouldn't exist in the world any longer: dragon blood. In addition to having countless mysterious properties, it's a powerful energy source that can be used to create devastating weapons. Ridge, Sardelle, and their allies must travel to the empire as part of a secret strike force to steal the dragon blood. If they fail, the Cofah will finally have the power to destroy all of Iskandia.




Balanced on the Blade's Edge


Book Description

Colonel Ridge Zirkander isn’t the model of military professionalism—he has a tendency to say exactly what’s on his mind, and his record has enough demerits to wallpaper the hull of an airship—but as the best fighter pilot in the Iskandian army, he’s used to a little leniency from his superiors. Until he punches the wrong diplomat in the nose and finds himself issued new orders: take command of a remote prison mine in the inhospitable Ice Blades Mountains. Ridge has never been in charge of anything larger than a flier squadron—what’s he supposed to do with a frozen fortress full of murderers and rapists? Not to mention the strange woman who shows up right before he arrives… Sardelle Terushan wakes from three hundred years in a mage stasis shelter, only to realize that she is the last of the Referatu, the sorcerers who once helped protect Iskandia from conquerors. Their subterranean mountain community was blown up in a treacherous sneak attack by soldiers who feared their power. Everyone Sardelle ever knew is dead, and the sentient soulblade she has been bonded to since her youth is buried in the core of the mountain. Further, what remains of her home has been infested by bloodthirsty miners commanded by the descendants of the very soldiers who destroyed her people. Sardelle needs help to reach her soulblade—her only link to her past and her last friend in the world. Her only hope is to pretend she’s one of the prisoners while trying to gain the commander’s trust. But lying isn’t her specialty, especially when the world has changed so much in the intervening centuries, and if Colonel Zirkander figures out who she truly is, he’ll be duty-bound to sentence her to the only acceptable punishment for sorcerers: death.




Stochastic Models in Life Insurance


Book Description

The book provides a sound mathematical base for life insurance mathematics and applies the underlying concepts to concrete examples. Moreover the models presented make it possible to model life insurance policies by means of Markov chains. Two chapters covering ALM and abstract valuation concepts on the background of Solvency II complete this volume. Numerous examples and a parallel treatment of discrete and continuous approaches help the reader to implement the theory directly in practice.




Cure Models


Book Description

Cure Models: Methods, Applications and Implementation is the first book in the last 25 years that provides a comprehensive and systematic introduction to the basics of modern cure models, including estimation, inference, and software. This book is useful for statistical researchers and graduate students, and practitioners in other disciplines to have a thorough review of modern cure model methodology and to seek appropriate cure models in applications. The prerequisites of this book include some basic knowledge of statistical modeling, survival models, and R and SAS for data analysis. The book features real-world examples from clinical trials and population-based studies and a detailed introduction to R packages, SAS macros, and WinBUGS programs to fit some cure models. The main topics covered include the foundation of statistical estimation and inference of cure models for independent and right-censored survival data, cure modeling for multivariate, recurrent-event, and competing-risks survival data, and joint modeling with longitudinal data, statistical testing for the existence and difference of cure rates and sufficient follow-up, new developments in Bayesian cure models, applications of cure models in public health research and clinical trials.




Plant Salt Tolerance


Book Description

Soil salinity is destroying several hectares of arable land every minute. Because remedial land management cannot completely solve the problem, salt tolerant crops or plant species able to remove excessive salt from the soil could contribute significantly to managing the salinity problem. The key to engineering crops for salt tolerance lies in a thorough understanding of the physiological mechanisms underlying the adaptive responses of plants to salinity. Plant Salt Tolerance: Methods and Protocols describes recent advances and techniques employed by researchers to understand the molecular and ionic basis of salinity tolerance and to investigate the mechanisms of salt stress perception and signalling in plants. With chapters written by leading international scientists, this book covers nearly 30 different methods, such as microelectrode and molecular methods, imaging techniques, as well as various biochemical assays. Written in the highly successful Methods in Molecular BiologyTM series format, chapters contain introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible, Plant Salt Tolerance: Methods and Protocols serves as an essential read for every student or researcher tackling various aspects of the salinity problem.




Statistical Methods for Engineers


Book Description

STATISTICAL METHODS FOR ENGINEERS, 3e, International Edition offers a balanced, streamlined one-semester introduction to Engineering Statistics that emphasizes the statistical tools most needed by practicing engineers.




Measurement Error in Longitudinal Data


Book Description

Longitudinal data is essential for understanding how the world around us changes. Most theories in the social sciences and elsewhere have a focus on change, be it of individuals, of countries, of organizations, or of systems, and this is reflected in the myriad of longitudinal data that are being collected using large panel surveys. This type of data collection has been made easier in the age of Big Data and with the rise of social media. Yet our measurements of the world are often imperfect, and longitudinal data is vulnerable to measurement errors which can lead to flawed and misleading conclusions. Measurement Error in Longitudinal Data tackles the important issue of how to investigate change in the context of imperfect data. It compiles the latest advances in estimating change in the presence of measurement error from several fields and covers the entire process, from the best ways of collecting longitudinal data, to statistical models to estimate change under uncertainty, to examples of researchers applying these methods in the real world. This book introduces the essential issues of longitudinal data collection, such as memory effects, panel conditioning (or mere measurement effects), the use of administrative data, and the collection of multi-mode longitudinal data. It also presents some of the most important models used in this area, including quasi-simplex models, latent growth models, latent Markov chains, and equivalence/DIF testing. Finally, the use of vignettes in the context of longitudinal data and estimation methods for multilevel models of change in the presence of measurement error are also discussed.




Laser-induced Graphene


Book Description

LIG is a revolutionary technique that uses a common CO2 infrared laser scriber, like the one used in any machine shop, for the direct conversion of polymers into porous graphene under ambient conditions. This technique combines the preparation and patterning of 3D graphene in a single step, without the use of wet chemicals. The ease in the structural engineering and excellent mechanical properties of the 3D graphene obtained have made LIG a versatile technique for applications across many fields. This book compiles cutting-edge research on LIG by different research groups all over the world. It discusses the strategies that have been developed to synthesize and engineer graphene, including controlling its properties such as porosity, composition, and surface characteristics. The authors are pioneers in the discovery and development of LIG and the book will appeal to anyone involved in nanotechnology, chemistry, environmental sciences, and device development, especially those with an interest in the synthesis and applications of graphene-based materials.




Nucleic Acid Transfection


Book Description

Gene Delivery into Mammalian Cells: An Overview on Existing Approaches Employed In Vitro and In Vivo, by Peter Hahn and Elizabeth Scanlan * Strategies for the Preparation of Synthetic Transfection Vectors, by Asier Unciti-Broceta, Matthew N. Bacon, and Mark Bradley * Cationic Lipids: Molecular Structure/Transfection Activity Relationships and Interactions with Biomembranes, by Rumiana Koynova and Boris Tenchov * Hyperbranched Polyamines for Transfection, by Wiebke Fischer, Marcelo Calderon, and Rainer Haag * Carbohydrate Polymers for Nonviral Nucleic Acid Delivery, by Antons Sizovs, Patrick M. McLendon, Sathya Srinivasachari, and Theresa M. Reineke * Cationic Liposome–Nucleic Acid Complexes for Gene Delivery and Silencing: Pathways and Mechanisms for Plasmid DNA and siRNA, by Kai K. Ewert, Alexandra Zidovska, Ayesha Ahmad, Nathan F. Bouxsein, Heather M. Evans, Christopher S. McAllister, Charles E. Samuel, and Cyrus R. Safinya * Chemically Programmed Polymers for Targeted DNA and siRNA Transfection, by Eveline Edith Salcher and Ernst Wagner * Photochemical Internalization: A New Tool for Gene and Oligonucleotide Delivery, by Kristian Berg, Maria Berstad, Lina Prasmickaite, Anette Weyergang, Pål K. Selbo, Ida Hedfors, and Anders Høgset * Visualizing Uptake and Intracellular Trafficking of Gene Carriers by Single-Particle Tracking, by N. Ruthardt and C. Bräuchle