Pathology and Biology of Human Germ Cell Tumors


Book Description

This book provides, for the first time, a detailed, up-to-date, holistic approach to the pathology and biology of germ cell tumors. The main focus is the complex histopathology of these tumors, but special considerations are also given to their morphologic variations in relation to age, gender and organ. Critical updates are provided on terminology and classification; the discussion of biology and pathogenesis includes references to many molecular genetic and immunohistochemical findings from recent stem cell research. Individual chapters are devoted to germ cell tumors at different anatomic locations, including not only the ovaries and testes but also the mediastinum and central nervous system, and pediatric tumors. All of the contributing authors are opinion leaders from universities of excellence in Europe and the United States. This monograph will be of wide interest to practitioners and researchers in many fields of medicine, including pathology, gynecology, urology, and pediatrics, as well as stem cell scientists.




Burned Bridge


Book Description

The building of the Berlin Wall in 1961 shocked the world. Ever since, the image of this impenetrable barrier between East and West, imposed by communism, has been a central symbol of the Cold War. Based on vast research in untapped archival, oral, and private sources, Burned Bridge reveals the hidden origins of the Iron Curtain, presenting it in a startling new light. Historian Edith Sheffer's unprecedented, in-depth account focuses on Burned Bridge-the intersection between two sister cities, Sonneberg and Neustadt bei Coburg, Germany's largest divided population outside Berlin. Sheffer demonstrates that as Soviet and American forces occupied each city after the Second World War, townspeople who historically had much in common quickly formed opposing interests and identities. The border walled off irreconcilable realities: the differences of freedom and captivity, rich and poor, peace and bloodshed, and past and present. Sheffer describes how smuggling, kidnapping, rape, and killing in the early postwar years led citizens to demand greater border control on both sides--long before East Germany fortified its 1,393 kilometer border with West Germany. It was in fact the American military that built the first barriers at Burned Bridge, which preceded East Germany's borderland crackdown by many years. Indeed, Sheffer shows that the physical border between East and West was not simply imposed by Cold War superpowers, but was in some part an improvised outgrowth of an anxious postwar society. Ultimately, a wall of the mind shaped the wall on the ground. East and West Germans became part of, and helped perpetuate, the barriers that divided them. From the end of World War II through two decades of reunification, Sheffer traces divisions at Burned Bridge with sharp insight and compassion, presenting a stunning portrait of the Cold War on a human scale.







Moon-face and Other Stories


Book Description

JACK LONDON (1876-1916), American novelist, born in San Francisco, the son of an itinerant astrologer and a spiritualist mother. He grew up in poverty, scratching a living in various legal and illegal ways -robbing the oyster beds, working in a canning factory and a jute mill, serving aged 17 as a common sailor, and taking part in the Klondike gold rush of 1897. This various experience provided the material for his works, and made him a socialist. "The son of the Wolf" (1900), the first of his collections of tales, is based upon life in the Far North, as is the book that brought him recognition, "The Call of the Wild" (1903), which tells the story of the dog Buck, who, after his master ́s death, is lured back to the primitive world to lead a wolf pack. Many other tales of struggle, travel, and adventure followed, including "The Sea-Wolf" (1904), "White Fang" (1906), "South Sea Tales" (1911), and "Jerry of the South Seas" (1917). One of London ́s most interesting novels is the semi-autobiographical "Martin Eden" (1909). He also wrote socialist treatises, autobiographical essays, and a good deal of journalism.




Diagnostic Molecular Biology


Book Description

Diagnostic Molecular Biology, Second Edition describes the fundamentals of molecular biology in a clear, concise manner with each technique explained within its conceptual framework and current applications of clinical laboratory techniques comprehensively covered. This targeted approach covers the principles of molecular biology, including basic knowledge of nucleic acids, proteins and chromosomes; the basic techniques and instrumentations commonly used in the field of molecular biology, including detailed procedures and explanations; and the applications of the principles and techniques currently employed in the clinical laboratory. Topics such as whole exome sequencing, whole genome sequencing, RNA-seq, and ChIP-seq round out the discussion. Fully updated, this new edition adds recent advances in the detection of respiratory virus infections in humans, like influenza, RSV, hAdV, hRV but also corona. This book expands the discussion on NGS application and its role in future precision medicine. - Provides explanations on how techniques are used to diagnosis at the molecular level - Explains how to use information technology to communicate and assess results in the lab - Enhances our understanding of fundamental molecular biology and places techniques in context - Places protocols into context with practical applications - Includes extra chapters on respiratory viruses (Corona)




The Human Teratomas


Book Description




Survival of Cancer Patients in Europe


Book Description

This book is a compilation and discussion of data on the survival of cancer patients in 12 European countries. Measures of incidence, survival and mortality are critical to the interpretation of data on progress in the fight against cancer, and in the evaluation of the overall effectiveness of cancer control programmes. Randomized controlled clinical trials have shown many modern protocols for cancer treatment to be more effective than earlier treatments, but until now, comparable population-based survival figures have raraly been available. EUROCARE is a concerted action among European cancer registries, aimed at estimating and comparing the survival of cancer patients in different European populations. The rationale behind this project is to optimize the comparability of survival data by using an agreed and standard definition of the diseases for which survival is to be compared, and by taking due account of basic demographic variables. The EUROCARE Working Group succeeded in collecting, checking and editing data on cancer survival from 30 cancer registries in 12 countries, and established a database covering some 800,000 cancer patients in the period 1978-85 and followed up to the end of 1990. This database forms the raw material for this monograph.




Driving the Soviets up the Wall


Book Description

The Berlin Wall was the symbol of the Cold War. For the first time, this path-breaking book tells the behind-the-scenes story of the communists' decision to build the Wall in 1961. Hope Harrison's use of archival sources from the former East German and Soviet regimes is unrivalled, and from these sources she builds a highly original and provocative argument: the East Germans pushed the reluctant Soviets into building the Berlin Wall. This fascinating work portrays the different approaches favored by the East Germans and the Soviets to stop the exodus of refugees to West Germany. In the wake of Stalin's death in 1953, the Soviets refused the East German request to close their border to West Berlin. The Kremlin rulers told the hard-line East German leaders to solve their refugee problem not by closing the border, but by alleviating their domestic and foreign problems. The book describes how, over the next seven years, the East German regime managed to resist Soviet pressures for liberalization and instead pressured the Soviets into allowing them to build the Berlin Wall. Driving the Soviets Up the Wall forces us to view this critical juncture in the Cold War in a different light. Harrison's work makes us rethink the nature of relations between countries of the Soviet bloc even at the height of the Cold War, while also contributing to ongoing debates over the capacity of weaker states to influence their stronger allies.




The Miracle Years


Book Description

Stereotypical descriptions showcase West Germany as an "economic miracle" or cast it in the narrow terms of Cold War politics. Such depictions neglect how material hardship preceded success and how a fascist past and communist sibling complicated the country's image as a bastion of democracy. Even more disappointing, they brush over a rich and variegated cultural history. That history is told here by leading scholars of German history, literature, and film in what is destined to become the volume on postwar West German culture and society. In it, we read about the lives of real people--from German children fathered by black Occupation soldiers to communist activists, from surviving Jews to Turkish "guest" workers, from young hoodlums to middle-class mothers. We learn how they experienced and represented the institutions and social forces that shaped their lives and defined the wider culture. We see how two generations of West Germans came to terms not only with war guilt, division from East Germany, and the Angst of nuclear threat, but also with changing gender relations, the Americanization of popular culture, and the rise of conspicuous consumption. Individually, these essays peer into fascinating, overlooked corners of German life. Together, they tell what it really meant to live in West Germany in the 1950s and 1960s. In addition to the editor, the contributors are Volker R. Berghahn, Frank Biess, Heide Fehrenbach, Michael Geyer, Elizabeth Heineman, Ulrich Herbert, Maria Höhn, Karin Hunn, Kaspar Maase, Richard McCormick, Robert G. Moeller, Lutz Niethammer, Uta G. Poiger, Diethelm Prowe, Frank Stern, Arnold Sywottek, Frank Trommler, Eric D. Weitz, Juliane Wetzel, and Dorothee Wierling.




The Korean War in World History


Book Description

" The Korean War in World History features the accomplishments of noted scholars over the last decade and lays the groundwork for the next generation of scholarship. These essays present the latest thinking on the Korean War, focusing on the relationship of one country to the war. William Stueck’s introduction and conclusion link each essay to the rich historiography of the event and suggest the war’s place within the history of the twentieth century. The Korean War had two very different faces. On one level the conflict was local, growing out of the internal conditions of Korea and fought almost entirely within the confines of a small Asian country located far from Europe. The fighting pitted Korean against Korean in a struggle to determine the balance of political power within the country. Yet the war had a huge impact on the international politics of the Cold War. Combat threatened to extend well beyond the peninsula, potentially igniting another global conflagration and leaving in its wake a much escalated arms race between the Western and Eastern blocs. The dynamics of that division remain today, threatening international peace and security in the twenty-first century. Contributors: Lloyd Gardner, Chen Jian, Allan R. Millett, Michael Schaller, and Kathryn Weathersby