Molecular Biology of the Cell
Author :
Publisher :
Page : 0 pages
File Size : 19,61 MB
Release : 2002
Category : Cells
ISBN : 9780815332183
Lipid Domains
Author :
Publisher : Academic Press
Page : 393 pages
File Size : 22,8 MB
Release : 2015-06-08
Category : Science
ISBN : 0128033274
Book Description
Current Topics in Membranes is targeted toward scientists and researchers in biochemistry and molecular and cellular biology, providing the necessary membrane research to assist them in discovering the current state of a particular field and in learning where that field is heading. This volume offers an up to date presentation of current knowledge in the field of Lipid Domains. - Written by leading experts - Contains original material, both textual and illustrative, that should become a very relevant reference material - The material is presented in a very comprehensive manner - Both researchers in the field and general readers should find relevant and up-to-date information
Cholesterol in Membrane Models
Author : Leonard X. Finegold
Publisher : CRC Press
Page : 298 pages
File Size : 45,59 MB
Release : 1992-12-15
Category : Science
ISBN : 9780849342073
Book Description
Cholesterol in Membrane Models provides the most recent summary available of basic molecular models and experiments in models of biological membranes. The book introduces the cell biology of cholesterol and covers the modeling of cholesterol in model membranes by the mean field and Monte Carlo theoretical methods. The experimental movement of cholesterol into model membranes and phase diagrams of cholesterol in these membranes by nuclear magnetic resonance and by thermal techniques using different lipid chain lengths are discussed. Light and electron microscopy that explore the spatial distribution of cholesterol in the model membrane are covered. The book also examines the use of infrared/Raman and neutron spectroscopy. Cholesterol in Membrane Models is an excellent learning resource, research tool, and reference for a wide range of experimental and theoretical scientists, including cellular biologists, biophysicists, biochemists, and molecular modelers.
Peptide-Lipid Interactions
Author : Sidney A. Simon
Publisher : Academic Press
Page : 606 pages
File Size : 23,35 MB
Release : 2002-11-13
Category : Science
ISBN : 0080925855
Book Description
This volume contains a comprehensive overview of peptide-lipid interactions by leading researchers. The first part covers theoretical concepts, experimental considerations, and thermodynamics. The second part presents new results obtained through site-directed EPR, electron microscopy, NMR, isothermal calorimetry, and fluorescence quenching. The final part covers problems of biological interest, including signal transduction, membrane transport, fusion, and adhesion. Key Features * world-renowned experts * state-of-the-art experimental methods * monolayers, bilayers, biological membranes * theoretical aspects and computer simulations * rafts * synaptic transmission * membrane fusion * signal transduction
Methods in Membrane Lipids
Author : Alex M. Dopico
Publisher : Springer Science & Business Media
Page : 1265 pages
File Size : 13,93 MB
Release : 2007-08-30
Category : Medical
ISBN : 1588296628
Book Description
This book presents a compendium of methodologies for the study of membrane lipids, varying from traditional lab bench experimentation to computer simulation and theoretical models. The volume provides a comprehensive set of techniques for studying membrane lipids with a strong biophysical emphasis. It compares the various available techniques including the pros and cons as seen by the experts.
The Biophysics of Cell Membranes
Author : Richard M. Epand
Publisher : Springer
Page : 224 pages
File Size : 17,88 MB
Release : 2017-09-25
Category : Science
ISBN : 9811062447
Book Description
This volume focuses on the modulation of biological membranes by specific biophysical properties. The readers are introduced to emerging biophysical approaches that mimick specific states (like membrane lipid asymmetry, membrane curvature, lipid flip-flop, lipid phase separation) that are relevant to the functioning of biological membranes. The first chapter describes innovative methods to mimic the prevailing asymmetry in biological membranes by forming asymmetrical membranes made of monolayers with different compositions. One of the chapters illustrates how physical parameters, like curvature and elasticity, can affect and modulate the interactions between lipids and proteins. This volume also describes the sensitivity of certain ion channels to mechanical forces and it presents an analysis of how cell shape is determined by both the cytoskeleton and the lipid domains in the membrane. The last chapter provides evidence that liposomes can be used as a minimal cellular model to reconstitute processes related to the origin of life. Each topic covered in this volume is presented by leading experts in the field who are able to present clear, authoritative and up-to-date reviews. The novelty of the methods proposed and their potential for a deeper molecular description of membrane functioning are particularly relevant experts in the areas of biochemistry, biophysics and cell biology, while also presenting clear and thorough introductions, making the material suitable for students in these fields as well.
Cholesterol
Author : Anna N. Bukiya
Publisher : Academic Press
Page : 1060 pages
File Size : 15,92 MB
Release : 2022-04-26
Category : Science
ISBN : 0323858589
Book Description
With Cholesterol, Drs. Anna Bukiya and Alex Dopico have compiled a comprehensive resource on biological and clinical aspects of cholesterol, spanning biophysics and biochemistry, as well as the latest pharmacological discoveries employed to tackle disorders associated with abnormal cholesterol levels. Early chapters on basic biology offer guidance in cholesterol lab chemistry, cholesterol metabolism and synthesis, molecular evolution of cholesterol and sterols, cholesterol peptides, and cholesterol modulation. Chapters on cellular and organismal development discuss cholesterol transport in blood, lipoproteins, and cholesterol metabolism; cholesterol detection in the blood; cellular cholesterol levels; hypercholesterolemia; and the role of cholesterol in early human development. Pathophysical specialists consider familial hypobetalipoproteinemia, critical illness and cholesterol levels, coronary artery disease, CESD, cholesterol and viral pathology, cholesterol and neurodegenerative disorders, and cholesterol and substance use disorders. A final section examines pharmacology of drug delivery systems targeting cholesterol related disorders, cholesterol receptors, cholesterol reduction, statins, citrate lyase, cyclodextrins, and clinical management. Cholesterol: From Biophysics and Biochemistry to Pathology and Pharmacology empowers researchers, students, and clinicians across various disciplines to advance new cholesterol-based studies, improve clinical management, and drive drug discovery. - Ties basic biology to clinical application and drug discovery - Provides methods and protocols for lab-based cholesterol research and clinical testing - Examines the latest pharmacological discoveries employed to tackle cholesterol related disorders - Includes chapter contributions from a wide range of specialists, uniting various disciplines
Liposomes, Lipid Bilayers and Model Membranes
Author : Georg Pabst
Publisher : CRC Press
Page : 482 pages
File Size : 22,96 MB
Release : 2014-03-04
Category : Medical
ISBN : 1466507098
Book Description
As a result of their unique physical properties, biological membrane mimetics, such as liposomes, are used in a broad range of scientific and technological applications. Liposomes, Lipid Bilayers and Model Membranes: From Basic Research to Application describes state-of-the-art research and future directions in the field of membranes, which has evolved from basic studies of the physicochemical properties of amphiphiles to their application in industry and medicine. Written by leading researchers in their fields, this book describes basic and applied research, and serves as a useful reference for both the novice and the expert. Part one covers a range of basic research topics, from theory and computational simulations to some of the most up-to-date experimental research. Topics discussed include soft matter physics of membranes, nonlamellar phases, extraction of molecules by amphiphiles, lipid models for membrane rafts, membrane dynamics, nanodiscs, microemulsions, active membranes, as well as interactions of bilayers with drugs or DNA to treat disease or for gene transfer, respectively. Part two of the book focuses on technological applications of amphiphiles, such as liposome-based nanoparticles for drug delivery, formulation of liposomes for prolonged in vivo circulation and functionalization for medical purposes, novel drug delivery systems for increased drug loading, and the use of tethered membranes for bio-sensing applications. Chapters also describe the use of liposomes in textile dyeing and how lipidic nanoparticles are used by the food industry.
Biochemistry of Lipids, Lipoproteins and Membranes
Author : Dennis E. Vance
Publisher : Elsevier
Page : 577 pages
File Size : 23,88 MB
Release : 1996-08-06
Category : Science
ISBN : 0080860923
Book Description
This is the third edition of this advanced textbook, written with two major objectives in mind. One is to provide an advanced textbook covering the major areas in the fields of lipid, lipoprotein, and membrane biochemistry, and molecular biology. The second objective is to provide a clear summary of these research areas for scientists presently working in these fields.The volume provides the basis for an advanced course for students in the biochemistry of lipids, lipoproteins and membranes. The book will satisfy the need for a general reference and review book for scientists studying lipids, proteins and membranes. Excellent up-to-date reviews are available on the various topics covered. A current, readable, and critical summary of these areas of research, it will allow scientists to become familiar with recent developments related to their own research interests, and will help clinical researchers and medical students keep abreast of developments in basic science that are important for subsequent clinical advances.
Lipid Bilayers
Author : J. Katsaras
Publisher : Springer Science & Business Media
Page : 304 pages
File Size : 19,93 MB
Release : 2013-06-29
Category : Science
ISBN : 366204496X
Book Description
Provides the reader with an up to date insight of the current state of the art in the field of lipid bilayer research and the important insights derived for the understanding of the complex and varied behaviour of biological membranes and its function.
