Life with Epidermolysis Bullosa (EB)


Book Description

Epidermolysis bullosa (EB) is a heterogenous group of genodermatoses characterized by the formation of blisters and erosions on skin and mucous membrans from birth on. The cause are mutations in the genes of structural proteins of the junction between epidermis and dermis. This book deals with the treatment of this skin disease itself and its many extracutaneous complications. There is no previous book which has been focused on the therapy and it will be based on evidence-based data derived from the world ́s largest cohort of inherited EB-patients, the American EB Registry. An important chapter will discuss gene therapy in hereditary EB which has been recently successfully performed within a localized skin site on a single EB patient as a proof-of-principle test. Given its unique collective contents, the monograph will provide the primary source for clinical informations of this oftentimes severe multiorgan disease.




Living with Epidermolysis Bullosa


Book Description

Living with Epidermolysis Bullosa has first-hand accounts written by parents and patients who are living or have lived with EB, and was compiled to help people in general understand how it is like to truly live with every form of Epidermolysis Bullosa; from the milder Simplex variants, who are nonetheless not simple to live with, to the more lethal, namely Junctional, whose patients usually succumb to before their first birthday. The stories you will read are from proud parents, or patients and their struggles and how they are coping. Some stories are sad, some are encouraging, and everything in between.




Butterfly Child


Book Description

Butterfly Child is the story of a mother's journey through grief and incredible challenges. From the stillbirth at full term of her first baby, followed by a miscarriage, to the birth of her son Nicky, diagnosed with Recessive Dystrophic Epidermolysis Bullosa, a rare skin blistering disorder that requires extensive wound care and is considered life threatening. Challenges include Insurance Companies refusal to cover the most basic needs for any EB patient to Silvia's trying to make sense of her situation, from a divorce to a remarriage and another scary pregnancy. Her youngest son, Connor, is 100% healthy and she never, ever, takes it for granted."




Jonny Kennedy


Book Description

Jonny Kennedy was the star of the Emmy-award winning documentary The Boy Whose Skin Fell Off. This is his moving, honest and uplifting story.




New Technologies in Dermatological Science and Practice


Book Description

While science and technology have been moving at speed in the last decade and major investments have been placed in Artificial Intelligence, blockchain technology, 3D printing, and gene editing, medical practice, including cutaneous medicine (otherwise known as Dermatology), is only just starting to follow these technological advances. This book is a timely intellectual investment for cutaneous medicine, addressing these particularly needed areas. It is written for medical educators, dermatology residents, practicing dermatologists, and medical researchers in the area of skin diseases, to alert them all to medical advances and up-and-coming technology and in the hope, it will inspire further novel methodology for the future of cutaneous medicine, in diagnosis and therapy.




Blistering Diseases


Book Description

This book is a comprehensive compendium of current knowledge on inherited and autoimmune blistering diseases that relates advances in our understanding of the pathogenetic mechanisms to management of the individual diseases. The aim is to provide a detailed reference for dermatologists who care for patients with these conditions and a useful “one-stop information shop” for specialists outside of dermatology. The book opens by describing the structure and biology of the epidermis and basement membrane zone and discussing the genes and proteins that are targets for mutations and autoantibodies. The role of the various diagnostic tests is explained, and clinical manifestations of the specific diseases are presented with the aid of many high-quality illustrations. The forms of treatment appropriate in specific conditions are then described in depth, with coverage of dressings, drugs, surgical procedures, gene therapy, and other novel approaches. Helpful algorithms are included both for testing and monitoring and for treatment.




Dermatological Diseases and Cumulative Life Course Impairment


Book Description

This publication presents currently available evidence about the extent to which dermatological diseases may, through their own nature as well as a multitude of comorbidities and their important interactions with social life, impair the life course of patients. Divided into four parts, the book starts with a brilliant introduction that highlights the importance of a life course approach in medicine from a medical as well as from a psychosocial point of view. The second part provides a basic presentation of the theoretical aspects of life course research and, more specifically, to the concepts of allostatic load and cumulative life course impairment (CLCI). The third part examines concepts related to CLCI, such as the 'quality of life in dermatology' or the 'major life changing decisions' influenced by dermatological diseases. The book concludes with an in-depth investigation of specific diseases where the concept of CLCI strikes as particularly relevant. The new and innovative evidence presented in this publication makes it essential reading to anyone who has to take social implications of skin diseases into account in their decision making: dermatologists, allergologists, pediatricians and general practitioners as well as researchers in medical sociology or opinion leaders in public health.




Tough Cookie


Book Description




European Handbook of Dermatological Treatments


Book Description

Dermatology is a specialty in the field of medicine which constantly changes at a vast rate. Alongside technology, new drugs, methods and treatments are continuously developed for the treatment of all common skin diseases. The first edition of the European Handbook of Dermatological Treatments received an overwhelming response from dermatovenereologists all over Europe. Its easy-to-read format, which is also used for this 2nd edition, is aimed at helping the physician to obtain comprehensive information at a glance. The three main sections listed alphabetically define the different diseases, the drugs available and the various methods of treatment used in dermatological practice. Each chapter begins with a brief section of the aetiology and pathogenesis of the skin disease, and leads into the description of the clinical characteristics, the diagnosis and the differential diagnosis. Followed by a detailed discussion on treatment methods, alternative methods are covered as well. Each section ends with a reference list for further reading. This new edition provides an excellent update including the newest developments of drugs, methods and treatments in dermatological practice, maintaining the clear structure and well-proven format. It is a very comprehensive and practical guide and should not be missed by those treating patients with skin diseases.




Diseases of the Oral Mucosa


Book Description

This textbook details the latest diagnostic and management options available when treating patients with diseases affecting the oral mucosa. It comprehensively covers the content required to successfully pass dermatology and stomatology board examinations, while being a valuable resource for dentistry trainees. Chapters cover aspects of mucosal immunity and clinical scores along with a range of diseases. Didactic features including learning objectives enable the reader to better extrapolate the key concepts covered in each chapter. Diseases of the Oral Mucosa: Study Guide and Review presents an in depth overview of the latest diagnostic tools and management options available for diseases of the oral mucosa and is an ideal resource for trainee and practising dentists, dermatologists and stomatologists preparing to sit board examinations.