Author : Charles W. Carter Jr.
Publisher : Elsevier
Page : 405 pages
File Size : 27,95 MB
Release : 2003-12-15
Category : Science
ISBN : 0080497098
Accurate molecular structures are vital for rational drug design and for structure-based functional studies directed toward the development of effective therapeutic agents and drugs. Crystallography can reliably predict structure, both in terms of folding and atomic details of bonding.* Methodological methods in crystals* Methodological methods data analysis
Author :
Publisher : Academic Press
Page : 465 pages
File Size : 40,6 MB
Release : 2011-02-14
Category : Science
ISBN : 0123859298
This volume provides descriptions of the occurrence of the UPR, methods used to assess it, pharmacological tools and other methodological approaches to analyze its impact on cellular regulation. The authors explain how these methods are able to provide important biological insights - This volume provides descriptions of the occurrence of the UPR, methods used to assess it, pharmacological tools and other methodological approaches to analyze its impact on cellular regulation - The authors explain how these methods are able to provide important biological insights
Author :
Publisher : Elsevier
Page : 412 pages
File Size : 35,92 MB
Release : 2006-10-06
Category : Science
ISBN : 0080468977
The ability of polypeptides to form alternatively folded, polymeric structures such as amyloids and related aggregates is being increasingly recognized as a major new frontier in protein research. This new volume of Methods in Enzymology along with Part B (volume 412) on Amyloid, Prions and other Protein Aggregates continue in the tradition of the first volume (309) in containing detailed protocols and methodological insights, provided by leaders in the field, into the latest methods for investigating the structures, mechanisms of formation, and biological activities of this important class of protein assemblies. - Presents detailed protocols - Includes troubleshooting tips - Provides coverage on structural biology, computational methods, and biology
Author : Charles W. Carter
Publisher : Gulf Professional Publishing
Page : 754 pages
File Size : 43,22 MB
Release : 1997
Category : Computer simulation
ISBN : 9780121827779
Annotation Accurate molecular structures is vital for rational drug design and for structure based functional studies directed toward the development of effective therapeutic agents and drugs. Crystallography can reliably predict structure, both in terms of folding and atomic details of bonding. * Phases * Map interpretation and refinement * Analysis and software.
Author :
Publisher : Academic Press
Page : 408 pages
File Size : 19,16 MB
Release : 2020-02-24
Category : Science
ISBN : 0128192143
Neutron Crystallography in Structural Biology, Volume 634, the latest volume in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Chapters in this updated release include Fundamentals of neutron crystallography in structural biology, Large crystal growth for neutron protein crystallography, Prospects for membrane protein crystals in NMX, IMAGINE: The neutron protein crystallography beamline at the high flux isotope reactor, The macromolecular neutron diffractometer at the spallation neutron source, Current status and near future plan of neutron protein crystallography at J-PARC, Neutron macromolecular crystallography at the European spallation source, and much more.
Author :
Publisher : Elsevier
Page : 581 pages
File Size : 12,39 MB
Release : 2000-08-09
Category : Science
ISBN : 0080496784
Volume 323 of Methods in Enzymology is dedicated to the energetics of biological macromolecules. Understanding the molecular mechanisms underlying a biological process requires detailed knowledge of the structural relationships within the system and an equally detailed understanding of the energetic driving forces that control the structural interactions. This volume presents modern thermodynamic techniques currently being utilized to study the energetic driving forces in biological systems. It will be a useful reference source and textbook for scientists and students whose goal is to understand the energetic relationships between macromoleculer structures and biological functions. This volume supplements Volumes 259 and Volume 295 of Methods in Enzymology.Key Features* Probing Stability of Helical Transmembrane Proteins* Energetics of Vinca Alkaloid Interactions with Tubulin* Deriving Complex Ligand Binding Formulas* Mathematical Modeling of Cooperative Interactions in Hemoglobin* Analysis of Interactions of Regulatory Protein TyrR with DNA* Parsing Free Energy of Drug-DNA Interactions* Use of Fluorescence as Thermodynamics Tool
Author :
Publisher : Elsevier
Page : 701 pages
File Size : 37,38 MB
Release : 2000-10-28
Category : Science
ISBN : 0080496830
The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant today--truly an essential publication for researchers in all fields of life sciences.
Author : Christopher A. Voigt
Publisher : Academic Press
Page : 734 pages
File Size : 22,93 MB
Release : 2011
Category : Bioengineering
ISBN : 0123850754
Synthetic biology encompasses a variety of different approaches, methodologies and disciplines and many different definitions exist. This volume covers topics such as measuring and engineering central dogma processes, mathematical and computational methods and next-generation DNA assembly and manipulation.
Author :
Publisher : Academic Press
Page : 475 pages
File Size : 10,62 MB
Release : 2012-12-31
Category : Medical
ISBN : 0123918707
This volume in the Methods in Enzymology series comprehensively covers Infectious Diseases, Immunotheraphy, Gene Medicine, Diagnostics and Toxicology of Nanomedicine. With an international board of authors, this volume is split into sections that cover subjects such as Nanomedicines in Immunotherapy, Nanomedicine toxicity, and Diagnostic Nanomedicine. - Comprehensively covers infectious diseases, immunotherapy, gene medicine, diagnostics, and toxicology of nanomedicine - International board of authors - Split into sections that cover subjects such as Nanomedicines in Immunotherapy, Nanomedicine Toxicity, and Diagnostic Nanomedicine
Author : Nejat Duzgunes
Publisher : Academic Press
Page : 503 pages
File Size : 12,43 MB
Release : 2012-03-30
Category : Medical
ISBN : 012391860X
This volume comprehensively covers cancer, cardiovascular and the central nervous system of nanomedicine. With an international board of authors, this volume is split into sections that cover subjects such as diabetes and nanotechnology as potential therapy, and nanomedicines for inflammatory diseases.
