Managing Hazardous Reactions and Compounds in Process Chemistry


Book Description

There is always potential for hazards during chemical reactions that can lead to accidents resulting in loss of time, equipment, products and harm to people. The hazards may result from uncontrolled exothermic reactions or secondary exothermic reactions such as decomposition of a reactant, reagent or product. Hazards may also occur from impurities or metal residues that can catalyze undesired exothermic reactions or decompositions. Many organic reactants, reagents, products as well as solvents have varying degrees of toxic effects and/or fire hazard if not handled properly. Improperly treated waste may also be a source of many hazards. Managing all these hazards effectively is very important for carrying out reactions safely, particularly on large scale. To achieve this goal, chemists and engineers need a clear understanding of the thermal characteristics of chemical reactions derived from accurate quantitative measurements and clear scientific knowledge of reaction mechanisms. They also need to build an expertise on handling toxic and flammable materials and proper procedures to waste treatment and disposal. To address these objectives, this book covers many topics on management of potential hazards in the chemical and pharmaceutical industries. The topics range from classical batch reactions to the latest innovative applications of continuous processes and flow chemistry. The applications range in scale from bench to manufacturing. The book contains 16 chapters on different aspects of managing chemical reaction hazards contributed by a group of internationally renowned leading chemical safety and hazard management experts. Their contributions make this book a valuable addition to the scientific literature




Organic Synthesis


Book Description

Organic Synthesis 5e provides a reaction-based approach to this important branch of organic chemistry. Updated and accessible, this eagerly-awaited revision offers a comprehensive foundation for graduate students coming from disparate backgrounds and knowledge levels, to provide them with critical working knowledge of basic reactions, stereochemistry and conformational principles. This reliable resource uniquely incorporates molecular modeling content, problems, and visualizations, and includes reaction examples and homework problems drawn from the latest in the current literature.? There have been advancements in organic reactions, particularly organometallic reactions, and there is a need to show how these advancements have influenced current organic synthesis. The goal is to revise and update the examples of reaction examples taken from the synthesis literature from about 2017-2023. The reactions illustrate those that are used most often in modern organic synthesis, but recent examples will show their current relevance.? Where new approaches and new reactions have been developed for organic synthesis, examples will be added as new material. - Provides new content, reaction examples, and study problems from recent research? - Features improved organization, new art, and new chapter content on process chemistry and green organic chemistry - Includes revised homework for each chapter, with new examples and questions?




Prudent Practices in the Laboratory


Book Description

Prudent Practices in the Laboratory-the book that has served for decades as the standard for chemical laboratory safety practice-now features updates and new topics. This revised edition has an expanded chapter on chemical management and delves into new areas, such as nanotechnology, laboratory security, and emergency planning. Developed by experts from academia and industry, with specialties in such areas as chemical sciences, pollution prevention, and laboratory safety, Prudent Practices in the Laboratory provides guidance on planning procedures for the handling, storage, and disposal of chemicals. The book offers prudent practices designed to promote safety and includes practical information on assessing hazards, managing chemicals, disposing of wastes, and more. Prudent Practices in the Laboratory will continue to serve as the leading source of chemical safety guidelines for people working with laboratory chemicals: research chemists, technicians, safety officers, educators, and students.




Chemistry for Sustainable Technologies


Book Description

Following the success of the first edition, this fully updated and revised book continues to provide an interdisciplinary introduction to sustainability issues in the context of chemistry and chemical technology. Its prime objective is to equip young chemists (and others) to more fully to appreciate, defend and promote the role that chemistry and its practitioners play in moving towards a society better able to control, manage and ameliorate its impact on the ecosphere. To do this, it is necessary to set the ideas, concepts, achievements and challenges of chemistry and its application in the context of its environmental impact, past, present and future, and of the changes needed to bring about a more sustainable yet equitable world. Progress since 2010 is reflected by the inclusion of the latest research and thinking, selected and discussed to put the advances concisely in a much wider setting – historic, scientific, technological, intellectual and societal. The treatment also examines the complexities and additional challenges arising from public and media attitudes to science and technology and associated controversies and from the difficulties in reconciling environmental protection and global development. While the book stresses the central importance of rigour in the collection and treatment of evidence and reason in decision-making, to ensure that it meets the needs of an extensive community of students, it is broad in scope, rather than deep. It is, therefore, appropriate for a wide audience, including all practising scientists and technologists.




Chemical Transformations of Carbon Dioxide


Book Description

​The series Topics in Current Chemistry Collections presents critical reviews from the journal Topics in Current Chemistry organized in topical volumes. The scope of coverage is all areas of chemical science including the interfaces with related disciplines such as biology, medicine and materials science. The goal of each thematic volume is to give the non-specialist reader, whether in academia or industry, a comprehensive insight into an area where new research is emerging which is of interest to a larger scientific audience. Each review within the volume critically surveys one aspect of that topic and places it within the context of the volume as a whole. The most significant developments of the last 5 to 10 years are presented using selected examples to illustrate the principles discussed. The coverage is not intended to be an exhaustive summary of the field or include large quantities of data, but should rather be conceptual, concentrating on the methodological thinking that will allow the non-specialist reader to understand the information presented. Contributions also offer an outlook on potential future developments in the field.




Green Chemical Engineering, Volume 12


Book Description

Green chemistry and chemical engineering belong together and this twelth volume in the successful Handbook of Green Chemistry series represents the perfect one-stop reference on the topic. Written by an international team of specialists with each section edited by international leading experts, this book provides first-hand insights into the field, covering chemical engineering process design, innovations in unit operations and manufacturing, biorefining and much more besides. An indispensable source for every chemical engineer in industry and academia.




Handbook for Process Safety in Laboratories and Pilot Plants


Book Description

Handbook for Process Safety in Laboratories and Pilot Plants Effectively manage physical and chemical risks in your laboratory or pilot plant In Handbook for Process Safety in Laboratories and Pilot Plants: A Risk-based Approach, the Center for Chemical Process Safety delivers a comprehensive and authoritative presentation of process safety procedures and methods for use in laboratories and pilot plants (LAPPs). Of the four broad hazard categories — chemical, physical, biological, and ionizing radiation — this book focuses on the two most common: chemical and physical hazards. It addresses the storage and handling of the hazardous materials associated with activities commonly performed in LAPPs and presents many of the physical and chemical analytical techniques used to verify and validate the efficacy of safety management systems. This book will present tools and techniques for effectively managing the risks in any laboratory or pilot plant using engineered and administrative controls, as well as the CCPS Risk Based Process Safety (RBPS) Management Systems. Readers will also find: A thorough introduction to process safety Comprehensive explorations of understanding hazards and risks, as well as managing risk with engineered controls, administrative controls, and RBPS Management Systems Practical discussions of how to learn from the experiences of your own LAPP and others Detailed case reports and examples, as well as practical tools, control banding strategies, and glass equipment design Perfect for any LAPP staff member working with or managing hazardous materials, Handbook for Process Safety in Laboratories and Pilot Plants: A Risk-based Approach will also benefit LAPP engineering and scientific professionals, LAPP technical support staff, and LAPP managers. The Center for Chemical Process Safety is a world leader in developing and distributing information on process safety management and technology. Since 1985, CCPS has published over 100 books in its process safety guidelines and concept series, 33 training modules as part of its Safety in Chemical Engineering Education series, and over 220 online offerings.




Prudent Practices in the Laboratory


Book Description

This volume updates and combines two National Academy Press bestsellers--Prudent Practices for Handling Hazardous Chemicals in Laboratories and Prudent Practices for Disposal of Chemicals from Laboratories--which have served for more than a decade as leading sources of chemical safety guidelines for the laboratory. Developed by experts from academia and industry, with specialties in such areas as chemical sciences, pollution prevention, and laboratory safety, Prudent Practices for Safety in Laboratories provides step-by-step planning procedures for handling, storage, and disposal of chemicals. The volume explores the current culture of laboratory safety and provides an updated guide to federal regulations. Organized around a recommended workflow protocol for experiments, the book offers prudent practices designed to promote safety and it includes practical information on assessing hazards, managing chemicals, disposing of wastes, and more. Prudent Practices for Safety in Laboratories is essential reading for people working with laboratory chemicals: research chemists, technicians, safety officers, chemistry educators, and students.




Advances in Organometallic Chemistry


Book Description

Advances in Organometallic Chemistry, Volume 67 contains authoritative review articles of worldwide known researchers on the field of organometallic chemistry, covering topics in organometallic synthesis, reactions, mechanisms, homogeneous catalysis, and more. Updates in this new volume include chapters on Group 6 Metal Fischer Carbene Complexes: Versatile Synthetic Building Blocks, Recent Advances in Transition-Metal-Catalyzed Cross-Coupling Reactions With Tosylhydrazones,Oxidative Functionalization of Late Transition Metal-Carbon Bond, and Biaryl Synthesis via C–H Bond Activation: Strategies and Methods. This book will benefit a wide range of researchers involved in organometallic chemistry, including those working on synthetic protocols, mechanistic studies and practical applications. - Contains contributions from leading authorities in the field of organometallic chemistry - Covers topics in organometallic synthesis, reactions, mechanisms, homogeneous catalysis, and more - Informs and updates readers on all the latest developments in the field - Carefully edited to provide easy-to-read material