Medical Bioinformatics and Biochemistry (diabormatics)


Book Description

The first edition of Medical Bioinformatics and Biochemistry (Diabormatics) explains how medical biochemistry and bioinformatics could be used as a tool for analyzing the research data related to disease diagnosis and treatment. Bioinformatics is an interdisciplinary approach that includes concepts of biotechnology, microbiology, molecular biology, medicine and forensic science. This book is based on the recent development in the research dynamics of medical bioinformatics, biochemistry and progress in these fields. The book provides reference material for students of medical and life sciences. The development in genomic sequencing and in silico biology has provided the data needed to accomplish comparisons of derived nucleotide and protein sequences. The results of analysis may be used to formulate and test hypotheses about biochemical function. This first edition provides readers with a practical guide covering the full scope of concepts in medical bioinformatics and biochemistry related to diabetes. The basic purpose of this book is for students of medical and life sciences to understand the research methods of biochemistry and bioinformatics. This includes storing, receiving, and analyzing data from databases using various in silico tools. This book is a useful source of knowledge for MBBS, B.Sc, M.Sc / M.D. / M.S. and Ph.D level students looking for an accessible introduction to the subject.




Integrative Human Biochemistry


Book Description

This book covers in detail the mechanisms for how energy is managed in the human body. The basic principles that elucidate the reactivity and physical interactions of matter are addressed and quantified with simple approaches. Three-dimensional representations of molecules are presented throughout the book so molecules can be viewed as unique entities in their shape and function. The book is focused on the molecular mechanisms of cellular processes in the context of human physiological situations such as fasting, feeding and physical exercise, in which metabolic regulation is highlighted. Furthermore the book uses key historical experiments that opened up new concepts in Biochemistry to further illustrate how the human body functions at molecular level, helping students to appreciate how scientific knowledge emerges. This book also: Elucidates the foundations of the molecular events of life Uses key historical experiments that opened up new concepts in Biochemistry to further illustrate how the human body functions at molecular level, helping students to appreciate how scientific knowledge emerges Provides realistic representations of molecules throughout the book Advance Praise for Integrative Human Biochemistry “This textbook provides a modern and integrative perspective of human biochemistry and will be a faithful companion to health science students following curricula in which this discipline is addressed. This textbook will be a most useful tool for the teaching community.” –Joan Guinovart Director of the Institute for Research in Biomedicine, Barcelona, Spain President-elect of the International Union of Biochemistry and Molecular Biology, IUBMB




Medical Biochemistry E-Book


Book Description

Brought to you in a thorough yet accessible manner, the new edition of Medical Biochemistry gives access to all of the latest information on basic and clinically focused genetic and molecular biology. Featuring a team of contributors that includes investigators involved in cutting-edge research as well as experienced clinicians, this updated medical textbook offers a unique combination of both research and practice that's ideal for today's problem-based integrated courses. Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. Relate biochemistry to everyday practice with the help of Clinical Boxes integrated into the text, and access in-depth coverage of important topics - including recent research in biochemistry - through Advanced Concept Boxes. Test your knowledge and improve retention with Active Learning Boxes at the conclusion of each chapter, and quickly review the most common lab tests performed with convenient Clinical Test Boxes. Effectively study the most updated information in biochemistry with the help of a dynamic, full-color design. Better understand the relationship between science and clinical practice with material organized by organ rather than system. Gain a thorough understanding of biomarkers and their uses with brand-new information on the subject. Access today's most recent research regarding Gene Therapy, Proteomics and Recombinant DNA Techniques, Role of Kidney in Metabolism, and Neurochemistry.




Genomics, Proteomics, and Metabolomics


Book Description

This book provides thorough coverage of high-throughput OMICs technologies for the monitoring of stem cells and regenerative medicine. Specific topics covered include the genomics, proteomics, and metabolomics aspects of regenerative medicine, metabolic profiling of mesenchymal stem cells, genome profiling of mesenchymal stem cells, OMICs monitoring of stem cell-derived exosomes, stem cell proteomics, lipidomics, OMICs profiling of cancer (stem) cells, and finally ethical considerations of OMICs-based investigations. Chapters are authored by world-renowned scientists who have valuable expertise in the field of OMICs and regenerative medicine. Genomics, Proteomics, and Metabolomics: Stem Cells Monitoring in Regenerative Medicine, part of Springer’s Stem Cell Biology and Regenerative Medicine series, is essential reading for researchers, clinicians, biologists, biochemists, and pharmaceutical experts conducting research in the fields of stem cell biology, molecular aspects of stem cell research, tissue engineering, regenerative medicine, cellular therapy, OMICs, bioinformatics, and ethics.







Bioinformatics Basics


Book Description

Scientists in the throes of research use an extensive data bank to access structural information on proteins and nucleic acids. Meanwhile, geneticists use a highly specialized form of software to analyze the hybridization pattern of DNA chips. The past decade has been tremendously successful for biotechnology and pharmaceutical industries. This success has been a result of astounding technical advancements in genome sequencing (genomics), protein identification (proteomics), and data analysis-collectively called bioinformatics. The exponential increase in computer processing and disk storage has served as a catalyst and been instrumental in the development of bioinformatics. Bioinformatics Basics: Applications in Biological Science and Medicine describes the origin of this field and the organization of public domain databases with an introductory tutorial for the services described. This book explains these services in a relatively simple fashion. Nevertheless, a biological background is necessary to understand and properly utilize the various software components and services described in this book. A basic biological background is also necessary for understanding the biological and medical significance of the collected data. Bioinformatics Basics is a fast growing field, and it will take some years for a stabilization to occur. Until then, hundreds of Internet sites allow us to search, compare, and manipulate this data in its relatively raw format. Bioinformatics Basics: Applications in Biological Science and Medicine concentrates on three major database clusters and relevant software tools that are maintained in the United States, Europe, and Japan, offering free access and analysis through the Internet.




Lipid Second Messengers


Book Description

Lipid Second Messengers provides detailed methodology for analysis of various lipid signaling pathways. Authoritative contributors explain the factors that regulate lipid second messenger production by agonist-activated enzymes and examine their products. Topics discussed include procedures used to measure lipid-derived mediators such as lysophospholipids, arachidonic acid, eicosanoids, anandamide, and ceramides, and the enzymes responsible for generating these messengers, such as phospholipases, prostaglandin endoperoxide synthases, and sphingomyelinase.




Biomedical Informatics


Book Description

This book provides a broad overview of the topic Bioinformatics with focus on data, information and knowledge. From data acquisition and storage to visualization, ranging through privacy, regulatory and other practical and theoretical topics, the author touches several fundamental aspects of the innovative interface between Medical and Technology domains that is Biomedical Informatics. Each chapter starts by providing a useful inventory of definitions and commonly used acronyms for each topic and throughout the text, the reader finds several real-world examples, methodologies and ideas that complement the technical and theoretical background. This new edition includes new sections at the end of each chapter, called "future outlook and research avenues," providing pointers to future challenges. At the beginning of each chapter a new section called "key problems", has been added, where the author discusses possible traps and unsolvable or major problems.




Biochemistry Explained


Book Description

Biochemistry Explained employs an innovative approach which has proven highly successful in the author's own classes. The author establishes a thorough understanding of the foundations of and common linkages between molecular structures and reactions, so that eventual interpretation of complex biochemical pathways and reactions is easy. All of the major molecular structures and biochemical pathways are explained, and, for the most part, these center on mammalian biochemistry. The text is supported by biochemical nomenclature and questions to bear in mind while reading. Higher learning sections are also provided for advanced students. Written in an informal, conversational style, this textbook will serve as an invaluable resource for any student who is struggling with the standard texts and for postgraduate students who need to refresh their knowledge.




A Bioinformatics Guide for Molecular Biologists


Book Description

Informatics can vastly assist progress in research and development in cell and molecular biology and biomedicine. However, many investigators are either unaware of the ways in which informatics can improve their research or find it inaccessible due to a feeling of "informatics anxiety." This sense of apprehension results from improper communication of the principles behind these approaches and of the value of the many tools available. In fact, many researchers are inherently distrustful of these tools. A more complete understanding of bioinformatics offered in A Bioinformatics Guide for Molecular Biologists will allow the reader to become comfortable with these techniques, encouraging their use-thus helping to make sense of the vast accumulation of data. To make these concepts more accessible, the editors approach the field of bioinformatics from the viewpoint of a molecular biologist, (1) arming the biologist with a basic understanding of the fundamental concepts in the field, (2) presenting approaches for using the tools from the standpoint of the data for which they are created, and (3) showing how the field of informatics is quickly adapting to the advancements in biology and biomedical technologies. All concepts are paired with recommendations for the appropriate programming environment and tools best suited to solve the particular problem at hand. It is a must-read for those interested in learning informatics techniques required for successful research and development in the laboratory.