Translational Research in Traumatic Brain Injury


Book Description

Traumatic brain injury (TBI) remains a significant source of death and permanent disability, contributing to nearly one-third of all injury related deaths in the United States and exacting a profound personal and economic toll. Despite the increased resources that have recently been brought to bear to improve our understanding of TBI, the developme




Neuroplasticity and Rehabilitation


Book Description

Brain plasticity is the focus of a growing body of research with significant implications for neurorehabilitation. This state-of-the-art volume explores ways in which brain-injured individuals may be helped not only to compensate for their loss of cognitive abilities, but also possibly to restore those abilities. Expert contributors examine the extent to which damaged cortical regions can actually recover and resume previous functions, as well as how intact regions are recruited to take on tasks once mediated by the damaged region. Evidence-based rehabilitation approaches are reviewed for a range of impairments and clinical populations, including both children and adults.




Neuroplasticity


Book Description

The real story of how our brains and nervous systems change throughout our lifetimes—with or without “brain training.” Fifty years ago, neuroscientists thought that a mature brain was fixed like a fly in amber, unable to change. Today, we know that our brains and nervous systems change throughout our lifetimes. This concept of neuroplasticity has captured the imagination of a public eager for self-improvement—and has inspired countless Internet entrepreneurs who peddle dubious “brain training” games and apps. In this book, Moheb Costandi offers a concise and engaging overview of neuroplasticity for the general reader, describing how our brains change continuously in response to our actions and experiences. Costandi discusses key experimental findings, and describes how our thinking about the brain has evolved over time. He explains how the brain changes during development, and the “synaptic pruning” that takes place before brain maturity. He shows that adult brains can grow new cells (citing, among many other studies, research showing that sexually mature male canaries learn a new song every year). He describes the kind of brain training that can bring about improvement in brain function. It's not gadgets and games that promise to “rewire your brain” but such sustained cognitive tasks as learning a musical instrument or a new language. (Costandi also notes that London cabbies increase their gray matter after rigorous training in their city's complicated streets.) He tells how brains compensate after stroke or injury; describes addiction and pain as maladaptive forms of neuroplasticity; and considers brain changes that accompany childhood, adolescence, parenthood, and aging. Each of our brains is custom-built. Neuroplasticity is at the heart of what makes us human.




Principles of Exercise Neuroscience


Book Description

It is well-established that the human nervous system is able to modify its functions in response to activity or experience. This response has been termed ‘neuroplasticity’ and involves the reorganisation of neural circuits that control human movement. Recent evidence suggests that the primary motor cortex (M1) can experience neuroplasticity following various types of physical activity. Although neuroplasticity can be stimulated in a variety of ways, recently, it has been reported following exercise, injury and during periods of rehabilitation. This book introduces the key concepts that underpin human motor control and its application to exercise science and rehabilitation. The topics covered here integrate research, theory and the clinical applications of exercise neuroscience that will support students, researchers and clinicians to understand how the nervous system responds, or adapts, to physical activity, training, rehabilitation and disease. The book uses a mix of neuromuscular physiology, electrophysiology and muscle physiology to provide a synthesis of current knowledge and research in the field of exercise neuroscience that specifically examines the effects of exercise training, injury and rehabilitation of the human nervous system. This is the first textbook of its kind that describes the neurological benefits of exercise, and will be a highly valuable text for undergraduate students studying exercise science, exercise physiology and physiotherapy.




Cognitive Plasticity in Neurologic Disorders


Book Description

This volume makes clear that the cognitive and behavioural symptoms of neurologic disorders and syndromes are dynamic and changing. Each chapter describes the neuroplastic processes at work in a particular condition, giving rise to these ongoing cognitive changes.




Neural Plasticity and Memory


Book Description

A comprehensive, multidisciplinary review, Neural Plasticity and Memory: From Genes to Brain Imaging provides an in-depth, up-to-date analysis of the study of the neurobiology of memory. Leading specialists share their scientific experience in the field, covering a wide range of topics where molecular, genetic, behavioral, and brain imaging techniq







Coaching the Brain


Book Description

Everything we do, and sense, happens through our brain. In Coaching the Brain: Practical Applications of Neuroscience to Coaching, highly experienced coaches Joseph O’Connor and Andrea Lages ask and answer the question: ‘How can we use our knowledge of the brain to help ourselves and others to learn, change, and develop?’. This book will show you how to apply insights from the latest neuroscience research in a practical way, in the fields of personal development, coaching and cognitive therapy. Accessible and practical, it begins with an overview of how the brain works along with an explanation of how our brain changes due to our actions and thoughts, illuminating how these habits can be changed through neuroplasticity. Understanding the neuroscience of goals and mental models helps us to work with and change them, and clarity about emotions and the emotional basis of values can help achieve happiness. Most importantly, neuroscience illuminates how we learn, as well as the power of expectations. The book also explores the key lessons we can take from neuroscience for high performance and leadership. Eminently accessible, this book gives you new tools to help yourself and others create better futures. As a whole, the book will provide you with a new respect for the depth and complexity of your thinking and emotions. Coaching the Brain: Practical Applications of Neuroscience to Coaching, with its clarity and practical application, will be essential reading for coaches in practice and in training, as well as leaders, coach supervisors and HR and L&D professionals, and will be a key text for academics and students of coaching and coaching psychology.




Stroke Rehabilitation


Book Description

Stroke Rehabilitation: Insights from Neuroscience and Imaging informs and challenges neurologists, rehabilitation therapists, imagers, and stroke specialists to adopt more restorative and scientific approaches to stroke rehabilitation based on new evidence from neuroscience and neuroimaging literatures. The fields of cognitive neuroscience and neuroimaging are advancing rapidly and providing new insights into human behavior and learning. Similarly, improved knowledge of how the brain processes information after injury and recovers over time is providing new perspectives on what can be achieved through rehabilitation. Stroke Rehabilitation explores the potential to shape and maximize neural plastic changes in the brain after stroke from a multimodal perspective. Active skill based learning is identified as a central element of a restorative approach to rehabilitation. The evidence behind core learning principles as well as specific learning strategies that have been applied to retrain lost functions of movement, sensation, cognition and language are also discussed. Current interventions are evaluated relative to this knowledge base and examples are given of how active learning principles have been successfully applied in specific interventions. The benefits and evidence behind enriched environments is reviewed with examples of potential application in stroke rehabilitation. The capacity of adjunctive therapies, such as transcranial magnetic stimulation, to modulate receptivity of the damaged brain to benefit from behavioral interventions is also discussed in the context of this multimodal approach. Focusing on new insights from neuroscience and imaging, the book explores the potential to tailor interventions to the individual based on viable brain networks.




Textbook of Neuromodulation


Book Description

Until recently, it was thought that the adult brain is modifiable only during early stages of ontogenesis. However, neurophysiological and neuroimaging studies now indicate that the mature human brain is, under certain conditions, capable of substantial neuroplastic changes. Neuroplasticity reflects the ability of the human brain to alter the pattern of neural activation in response to previous experience, and recent findings indicate that the effects of experience can lead to both structural as well as functional reorganization. It has been shown that pathological neuroplastic changes can be reverted/normalized and that the modulation of the neuroplastic changes can be paralleled by improvement of the patient's status. However, there is a gap between the potential of neuromodulation, technical progress and actual preparedness of medical personnel to provide this type of treatment. A prevalent opinion among medical professionals indicates that training programs and educational materials in neuromodulatory techniques are well needed and appreciated. Neuromodulation will focus on the description and discussion of methods currently available for invasive and non-invasive neuromodulation, their clinical potential, significance and practical applications. In order to facilitate understanding of the topic, the initial part of the textbook will review neurophysiological systems involved in neuromodulation and will provide readers with basic principles of neuroplasticity that constitutes the rationale for neuromodulation in human medicine. Additionally, the clinical use of these techniques will be described with special regard to safety and avoidance of complications.