› › Models And Algorithms For Genome Evolution

Models and Algorithms for Genome Evolution

Author : Cedric Chauve

Publisher : Springer Science & Business Media

Page : 329 pages

File Size : 18,42 MB

Release : 2013-09-17

Category : Computers

ISBN : 1447152980

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Book Description

This authoritative text/reference presents a review of the history, current status, and potential future directions of computational biology in molecular evolution. Gathering together the unique insights of an international selection of prestigious researchers, this must-read volume examines the latest developments in the field, the challenges that remain, and the new avenues emerging from the growing influx of sequence data. These viewpoints build upon the pioneering work of David Sankoff, one of the founding fathers of computational biology, and mark the 50th anniversary of his first scientific article. The broad spectrum of rich contributions in this essential collection will appeal to all computer scientists, mathematicians and biologists involved in comparative genomics, phylogenetics and related areas.



Sequence — Evolution — Function

Author : Eugene V. Koonin

Publisher : Springer Science & Business Media

Page : 482 pages

File Size : 18,27 MB

Release : 2013-06-29

Category : Science

ISBN : 1475737831

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Book Description

Sequence - Evolution - Function is an introduction to the computational approaches that play a critical role in the emerging new branch of biology known as functional genomics. The book provides the reader with an understanding of the principles and approaches of functional genomics and of the potential and limitations of computational and experimental approaches to genome analysis. Sequence - Evolution - Function should help bridge the "digital divide" between biologists and computer scientists, allowing biologists to better grasp the peculiarities of the emerging field of Genome Biology and to learn how to benefit from the enormous amount of sequence data available in the public databases. The book is non-technical with respect to the computer methods for genome analysis and discusses these methods from the user's viewpoint, without addressing mathematical and algorithmic details. Prior practical familiarity with the basic methods for sequence analysis is a major advantage, but a reader without such experience will be able to use the book as an introduction to these methods. This book is perfect for introductory level courses in computational methods for comparative and functional genomics.



Evolution as Computation

Author : Laura F. Landweber

Publisher : Springer Science & Business Media

Page : 348 pages

File Size : 45,32 MB

Release : 2012-12-06

Category : Computers

ISBN : 364255606X

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Book Description

The study of the genetic basis for evolution has flourished in this century, as well as our understanding of the evolvability and programmability of biological systems. Genetic algorithms meanwhile grew out of the realization that a computer program could use the biologically-inspired processes of mutation, recombination, and selection to solve hard optimization problems. Genetic and evolutionary programming provide further approaches to a wide variety of computational problems. A synthesis of these experiences reveals fundamental insights into both the computational nature of biological evolution and processes of importance to computer science. Topics include biological models of nucleic acid information processing and genome evolution; molecules, cells, and metabolic circuits that compute logical relationships; the origin and evolution of the genetic code; and the interface with genetic algorithms and genetic and evolutionary programming.



Next Generation Sequencing

Author : Jerzy Kulski

Publisher : BoD – Books on Demand

Page : 466 pages

File Size : 18,10 MB

Release : 2016-01-14

Category : Medical

ISBN : 9535122401

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Book Description

Next generation sequencing (NGS) has surpassed the traditional Sanger sequencing method to become the main choice for large-scale, genome-wide sequencing studies with ultra-high-throughput production and a huge reduction in costs. The NGS technologies have had enormous impact on the studies of structural and functional genomics in all the life sciences. In this book, Next Generation Sequencing Advances, Applications and Challenges, the sixteen chapters written by experts cover various aspects of NGS including genomics, transcriptomics and methylomics, the sequencing platforms, and the bioinformatics challenges in processing and analysing huge amounts of sequencing data. Following an overview of the evolution of NGS in the brave new world of omics, the book examines the advances and challenges of NGS applications in basic and applied research on microorganisms, agricultural plants and humans. This book is of value to all who are interested in DNA sequencing and bioinformatics across all fields of the life sciences.



Biological Sequence Analysis

Author : Richard Durbin

Publisher : Cambridge University Press

Page : 372 pages

File Size : 48,44 MB

Release : 1998-04-23

Category : Science

ISBN : 113945739X

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Book Description

Probabilistic models are becoming increasingly important in analysing the huge amount of data being produced by large-scale DNA-sequencing efforts such as the Human Genome Project. For example, hidden Markov models are used for analysing biological sequences, linguistic-grammar-based probabilistic models for identifying RNA secondary structure, and probabilistic evolutionary models for inferring phylogenies of sequences from different organisms. This book gives a unified, up-to-date and self-contained account, with a Bayesian slant, of such methods, and more generally to probabilistic methods of sequence analysis. Written by an interdisciplinary team of authors, it aims to be accessible to molecular biologists, computer scientists, and mathematicians with no formal knowledge of the other fields, and at the same time present the state-of-the-art in this new and highly important field.



Computational Molecular Evolution

Author : Ziheng Yang

Publisher : Oxford University Press, USA

Page : 374 pages

File Size : 27,40 MB

Release : 2006-10-05

Category : Medical

ISBN : 0198566999

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Book Description

This book describes the models, methods and algorithms that are most useful for analysing the ever-increasing supply of molecular sequence data, with a view to furthering our understanding of the evolution of genes and genomes.



Bioinformatics and Molecular Evolution

Author : Paul G. Higgs

Publisher : John Wiley & Sons

Page : 532 pages

File Size : 33,31 MB

Release : 2013-04-30

Category : Science

ISBN : 1118697065

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Book Description

In the current era of complete genome sequencing, Bioinformatics and Molecular Evolution provides an up-to-date and comprehensive introduction to bioinformatics in the context of evolutionary biology. This accessible text: provides a thorough examination of sequence analysis, biological databases, pattern recognition, and applications to genomics, microarrays, and proteomics emphasizes the theoretical and statistical methods used in bioinformatics programs in a way that is accessible to biological science students places bioinformatics in the context of evolutionary biology, including population genetics, molecular evolution, molecular phylogenetics, and their applications features end-of-chapter problems and self-tests to help students synthesize the materials and apply their understanding is accompanied by a dedicated website - www.blackwellpublishing.com/higgs - containing downloadable sequences, links to web resources, answers to self-test questions, and all artwork in downloadable format (artwork also available to instructors on CD-ROM). This important textbook will equip readers with a thorough understanding of the quantitative methods used in the analysis of molecular evolution, and will be essential reading for advanced undergraduates, graduates, and researchers in molecular biology, genetics, genomics, computational biology, and bioinformatics courses.



Molecular and Genome Evolution

Author : Dan Graur

Publisher : Sinauer

Page : 0 pages

File Size : 13,21 MB

Release : 2015-01-01

Category : Science

ISBN : 9781605354699

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Book Description

This book describes the driving forces behind the evolutionary process at the molecular and genome levels, the effects of the various molecular mechanisms on the structure of genes, proteins, and genomes, the methodology and the analytical tools involved in dealing with molecular data from an evolutionary perspective, and the logic of evolutionary hypothesis testing. Evolutionary phenomena at the molecular level are detailed in a way that can be understood without much prerequisite knowledge of molecular biology, evolution, or mathematics. Numerous examples that support and clarify the theoretical arguments and methodological discussions are included.



Algorithms in Bioinformatics

Author : Martin Frith

Publisher : Springer

Page : 336 pages

File Size : 47,52 MB

Release : 2016-08-08

Category : Computers

ISBN : 3319436813

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Book Description

This book constitutes the refereed proceedings of the 16th International Workshop on Algorithms in Bioinformatics, WABI 2016, held in Aarhus, Denmark. The 25 full papers together with 2 invited talks presented were carefully reviewed and selected from 54 submissions. The selected papers cover a wide range of topics from networks, tophylogenetic studies, sequence and genome analysis, comparative genomics, and mass spectrometry data analysis.



Basic and Applied Aspects of Biopesticides

Author : K. Sahayaraj

Publisher : Springer

Page : 387 pages

File Size : 49,82 MB

Release : 2014-07-10

Category : Technology & Engineering

ISBN : 8132218779

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Book Description

Currently, the major challenge of humanity is focused on population growth through agricultural production in order to meet the demand for food. The food crunch is mainly due to pest and disease. Traditional methods, synthetic insecticides and microbicides cause health hazards to human beings, domestic animals and also affect our immediate environments. Serious concerns were implemented by both developing and developed countries as Integrated Pest Management (IPM) and Bio-intensive Integrated Pest Management (BIPM) systems where biopesticides play an important role worldwide. The available books are limited to particular aspects of biopesticides. Hence, it is imperative to bring out a holistic documentation which will provide the reader information on all aspects of biopesticides. The book consists of five sections namely microbials, botanicals, natural enemies semio- chemicals and biotechnology and equipments, bioinformatics tools and IPM. In Section I, microbial deals with utilization of Bacillus in control of phytonematodes; biological control of pest and diseases with fluorescent pseudomonads, entomopathogenic fungus and entomopathogenic nematodes in pest management, microbial viral insecticides and microbial elicitors to induce immunity for plant disease control in chilli and tomato. Importance of plant essential oils, botanicals in endocrine disruption, relevance of botanicals and use of plant volatile on pest management has been discussed in Section II. Importance and role of reduviidae, weaver ants, ground beetles, Odonatas, spiders in biological control has been discussed in Section III. In addition, genetic improvement of biocontrol agents for sustainable pest management has also been highlighted. In Section IV, classical practices and pheromone, kairomonal enhancement to natural enemies and use of transgenic plants in insect control are highlighted. Equipment and their application methodologies for application of biopesticides; relevance of bioinformatics in biopesticides management; pest management of soybean, bio fouling and eco friendly antifoulants have been highlighted in Section V. Each chapter has objectives and conclusion along with recommendations.