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Molecular Signaling in Spermatogenesis and Male Infertility

Author : Rajender Singh

Publisher : CRC Press

Page : 346 pages

File Size : 47,98 MB

Release : 2019-11-06

Category : Medical

ISBN : 0429534426

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Book Description

Spermatogenesis involves the coordination of a number of signaling pathways, which culminate into production of sperm. Its failure results in male factor infertility, which can be due to hormonal, environmental, genetic or other unknown factors. This book includes chapters on most of the signaling pathways known to contribute to spermatogenesis. Latest research in germ cell signaling like the role of small RNAs in spermatogenesis is also discussed. This book aims to serve as a reference for both clinicians and researchers, explaining possible causes of infertility and exploring various treatment methods for management through the basic understanding of the role of molecular signaling. Key Features Discusses the signaling pathways that contribute to successful spermatogenesis Covers comprehensive information about Spermatogenesis at one place Explores the vital aspects of male fertility and infertility Explains the epigenetic regulation of germ cell development and fertility Highlights the translational opportunities in molecular signaling in testis



Infertility in the Male

Author : Larry I. Lipshultz

Publisher : Cambridge University Press

Page : 691 pages

File Size : 14,76 MB

Release : 2009-09-24

Category : Medical

ISBN : 1139483242

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Book Description

The new edition of this canonical text on male reproductive medicine will cement the book's market-leading position. Practitioners across many specialties - including urologists, gynecologists, reproductive endocrinologists, medical endocrinologists and many in internal medicine and family practice – will see men with suboptimal fertility and reproductive problems. The book provides an excellent source of timely, well-considered information for those training in this young and rapidly evolving field. While several recent books provide targeted 'cookbooks' for those in a male reproductive laboratory, or quick reference for practising generalists, the modern, comprehensive reference providing both a background for male reproductive medicine as well as clinical practice information based on that foundation has been lacking until now. The book has been extensively revised with a particular focus on modern molecular medicine. Appropriate therapeutic interventions are highlighted throughout.



The Sertoli Cell

Author : Lonnie Dee Russell

Publisher :

Page : 840 pages

File Size : 47,1 MB

Release : 1993

Category : Sertoli cells

ISBN :

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The Genetics of Male Infertility

Author : Douglas T. Carrell

Publisher : Springer Science & Business Media

Page : 337 pages

File Size : 15,15 MB

Release : 2007-11-08

Category : Medical

ISBN : 1597451762

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Book Description

In this book, twenty-one researchers and clinicians review the study of the genetics of male infertility, the tools available in the laboratory and clinic, the current state of knowledge, and the future of research and translation into clinical diagnostics and treatments. New tools discussed are discussed. This book therefore serves as a guide to evidence-based clinical applications, and a preview of future possibilities.



Sertoli Cell Biology

Author : Michael K. Skinner

Publisher : Elsevier

Page : 511 pages

File Size : 43,54 MB

Release : 2004-11-23

Category : Science

ISBN : 0080492282

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Book Description

Sertoli cells assist in the production of sperm in the male reproductive system. This book provides a state-of-the-art update on the topic of sertoli cells and male reproduction. It addresses such highly topical areas as stem cells, genomics, and molecular genetics, as well as provides historical information on the discovery of this type of cell, and the pathophysiology of male infertility. * Presents the state-of-the-art research on topics such as stem cell research, transplantation and genomics* Includes contributions from leaders in the field, including several members of the National Academy of Science



The Testis

Author : Henry G. Burger

Publisher :

Page : 464 pages

File Size : 30,59 MB

Release : 1981

Category : Medical

ISBN :

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Reproductomics

Author : José A. Horcajadas

Publisher : Academic Press

Page : 428 pages

File Size : 39,88 MB

Release : 2018-07-13

Category : Medical

ISBN : 0128126760

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Book Description

Recent advances in genomic and omics analysis have triggered a revolution affecting nearly every field of medicine, including reproductive medicine, obstetrics, gynecology, andrology, and infertility treatment. Reproductomics: The –Omics Revolution and Its Impact on Human Reproductive Medicine demonstrates how various omics technologies are already aiding fertility specialists and clinicians in characterizing patients, counseling couples towards pregnancy success, informing embryo selection, and supporting many other positive outcomes. A diverse range of chapters from international experts examine the complex relationship between genomics, transcriptomics, proteomics, and metabolomics and their role in human reproduction, identifying molecular factors of clinical significance. With this book Editors Jaime Gosálvez and José A. Horcajadas have provided researchers and clinicians with a strong foundation for a new era of personalized reproductive medicine. - Thoroughly discusses how genomics and other omics approaches aid clinicians in various areas of reproductive medicine - Identifies specific genomic and molecular factors of translational value in treating infertility and analyzing patient data - Features chapter contributions by leading international experts



Clinical Management of Male Infertility

Author : Giorgio Cavallini

Publisher : Springer

Page : 180 pages

File Size : 17,68 MB

Release : 2014-10-20

Category : Health & Fitness

ISBN : 3319085034

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Book Description

This book provides andrologists and other practitioners with reliable, up-to-date information on all aspects of male infertility and is designed to assist in the clinical management of patients. Clear guidance is offered on classification of infertility, sperm analysis interpretation and diagnosis. The full range of types and causes of male infertility are then discussed in depth. Particular attention is devoted to poorly understood conditions such as unexplained couple infertility and idiopathic male infertility, but the roles of diverse disorders, health and lifestyle factors and environmental pollution are also fully explored. Research considered stimulating for the reader is highlighted, reflecting the fascinating and controversial nature of the field. International treatment guidelines are presented and the role of diet and dietary supplements is discussed in view of their increasing importance. Clinicians will find that the book’s straightforward approach ensures that it can be easily and rapidly consulted.



Endocrinology of the Testis and Male Reproduction

Author : Manuela Simoni

Publisher : Springer

Page : 1364 pages

File Size : 20,63 MB

Release : 2017-09-18

Category : Medical

ISBN : 9783319444406

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Book Description

This book provides a comprehensive overview of endocrinology of the male reproductive system, explaining how it works and how, sometimes, it fails to work. World-class specialists present state of the art knowledge on all aspects, including anatomy, physiology, molecular biology, genetics, pathophysiology, clinical manifestations of testicular diseases, endocrine aspects of andrological and sexual diseases, and therapy. Extensive consideration is given to sexual development, testicular function, the clinical approach to disorders of male reproduction, male hypogonadism, sexual dysfunction, and male infertility. In addition, sociodemographic, psychological, and ethical aspects of male reproductive disorders are discussed. The book is intended as a major reference for endocrinologists, andrologists, and sexologists, as well as basic and clinical scientists. It is published as part of the SpringerReference program, which delivers access to living editions constantly updated through a dynamic peer-review publishing process.



Introduction to Mammalian Reproduction

Author : Daulat Tulsiani

Publisher : Springer Science & Business Media

Page : 405 pages

File Size : 40,11 MB

Release : 2012-12-06

Category : Science

ISBN : 146150273X

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Book Description

Introduction to Mammalian Reproduction is a welcome contribution to the fields of gametogenesis, gamete transport, fertilization, and reproduction technologies. Key topics covered include: *formation and maturation of male gametes; *morphology and physiology of female gametes; *how the sperm meets the egg; *sperm-egg fusion, egg activation, and implantation of fertilized egg; *assisted reproduction and environmental chemicals that have an effect on formation and function of male and female gametes. This book is for both researchers and students involved in reproductive biology.