Mouse Escape The Maze Vol. 6


Book Description

The mouse is trapped inside the walls and needs your help to escape so it can be a free mouse! Help him escape by playing through the mazes in this fun challenging maze book with many levels of difficulty. This maze book is sure to help improve concentration and help you learn problem solving and critical thinking skills. Collect all 50 volumes and have a great time solving mazes! For all ages, kids to adults.




Behavioral Genetics of the Mouse: Volume 1, Genetics of Behavioral Phenotypes


Book Description

The first volume in the new Cambridge Handbooks in Behavioral Genetics series, Behavioral Genetics of the Mouse provides baseline information on normal behaviors, essential in both the design of experiments using genetically modified or pharmacologically treated animals and in the interpretation and analyses of the results obtained. The book offers a comprehensive overview of the genetics of naturally occurring variation in mouse behavior, from perception and spontaneous behaviors such as exploration, aggression, social interactions and motor behaviors, to reinforced behaviors such as the different types of learning. Also included are numerous examples of potential experimental problems, which will aid and guide researchers trying to troubleshoot their own studies. A lasting reference, the thorough and comprehensive reviews offer an easy entrance into the extensive literature in this field, and will prove invaluable to students and specialists alike.




I Moved Your Cheese


Book Description

The author of Negotiating the Impossible “tackles our assumptions about business and life with humor, zest, and wisdom in this delightful fable” (Daniel H. Pink, New York Times-bestselling author). If you were a mouse trapped in a maze and someone kept moving the cheese, what would you do? In a world where most mice dutifully accept their circumstances, ask no questions, and keep chasing the cheese, Deepak Malhotra tells an inspiring story about three unique and adventurous mice—Max, Big, and Zed—who refuse to accept their reality as given. I Moved Your Cheese reveals what is possible when we finally discard long-held and widely accepted assumptions about how we should live our lives. After all, achieving extraordinary success, personal or professional, has always depended on the ability to challenge assumptions, reshape the environment, and play by a different set of rules—our own. But rejecting deeply ingrained beliefs is not easy. As Zed explains, “You see, Max, the problem is not that the mouse is in the maze, but that the maze is in the mouse.” “Deepak Malhotra allows you to glimpse a world of your own making without the limits and barriers that others create.” —Stephen R. Covey, New York Times-bestselling author of The 7 Habits of Highly Effective People “A magnificent story with a powerful message. As someone who has encouraged scores of professionals into breaking through the maze and defining their own pursuits, I find this to be a gem of a book.” —Vinod Khosla, cofounder, former CEO and Chairman, Sun Microsystems, and founder, Khosla Ventures “This book’s message is both profound and durable. Malhotra has left the maze, and so can we.” —Foreword Reviews




I Moved Your Cheese


Book Description

With more than twenty - five million copies in print, Who Moved My Cheese? has become a phenomenon. It does offer some reasonable advice about adapting to change. It's certainly true that some of the events shaping our lives are beyond our control, and instead of struggling against them we must adapt and move on. But for all its good intentions, ..




Untangling the Role of Tau in Physiology and Pathology


Book Description

This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.




Biology of Cognitive Aging: Model Systems, Technologies and beyond


Book Description

Welcome! We, humans, tend to experience forgetfulness when we get old. The forgetfulness may become more serious memory impairment, dementia. Presumably, we have known it for a long time, but we still do not know the mechanism behind. A normal part of forgetfulness is called age-related memory impairment (AMI), which is considered the first step towards mild cognitive impairment (MCI; transition state) and dementia (disease state). The majority of dementia is attributable to Alzheimer’s disease (AD). Progression to dementia occurs at a high rate in patients with AMI. This eBook covers exciting but yet challenging field of cognitive aging. AMI is specific to neural tissues of the brain and is considered to be segmental aging. It happens not only to humans but also to a variety of species. Learning and memory are vulnerable to aging in a wide variety of model species, including worms, fruit flies, insects, snails, fishes, and rodents. Aging specifically reduces the ability to learn new information but leaves “old” memories and procedural memory intact. A comparative approach including the use of model systems seems to facilitate understanding of the molecular mechanisms that lead to AMI and AD. We advocate research on model systems. This eBook also provides the first manuscript co-authored with an AD patient to create a feedback loop from patients incorporated into research. We also included a manuscript on the semi-automated system that was inspired by such a feedback. Those may place a nice flavor to this exciting series of comparative research on cognitive aging. We hope you enjoy this eBook. Warm regards, Shin Murakami, Ph.D.







Emerging Mechanisms in Neuronal Signaling: From Cell Biology to Pathogenesis


Book Description

This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.




The Alzheimer's Disease Challenge


Book Description

Alzheimer’s disease is undoubtedly the major health challenge of our Century with significant social and economic consequences. This Frontiers eBook offers a contribution of 39 innovative papers on the multidimensional and crucial problem of Alzheimer’s disease management and treatment. Several perspectives, research updates, and trials describing methods on potential diagnosis and treatment are presented including biological mechanisms, biomarkers and risk factors for an early and efficient prognosis, diagnosis and prevention. Additionally, while the rapidly increasing Alzheimer’s disease population demands holistic solutions and clinical studies with new therapeutic target approaches, several of the contributive papers present promising drugs targeting Alzheimer’s disease treatment. We give our deepest acknowledgment to all the authors for their important and innovative contributions, to the reviewers for their valuable recommendations on improving the submitting studies and all the Frontiers Editorial team for continuous support.