Investigation of Post-Patient Tapered Monolithic Optics for Mammography


Book Description

Polycapillary x-ray optics, arrays of hollow capillary tubes used to guide x rays by total reflectance, have been shown to have potential in medical imaging at mammographic energies. Placing these optics after the object to be imaged provides very efficient rejection of Compton scatter because of the low angular acceptance of the capillaries. A Polycapillary tapered optic produced reduction in scatter fraction of a factor of 5 at 27 keV and 3 at 45 keV for a 53 mm thick polymethyl methacrylate phantom. The contrast enhancement was a factor of 2 at 27 keV and 1.5 at 45 keV. The scatter fraction and contrast data performed with energy sensitive and imaging detectors were in good agreement. A detailed calculation for comparing these broadband and monoenergenic-input scatter fraction data was performed. The agreement provides an innovative new way to - predict the effect of input spectrum on contrast of an image at different energies. The PI also participated, as part of his training, in a variety of other imaging measurements at mammographic energies, including the use of DCC optics.




Direct Digital Mammography Using Capillary Optics


Book Description

The overall objective of this proposal is to develop a mammographic system with extremely high scatter rejection and dynamic range, good resolution and low patient dose. This will be accomplished by developing a direct x-ray detector interfaced with a capillary x-ray optic in an appropriately designed mammographic system. Measurements have been performed of transmission and absorbence of single capillaries. Preliminary measurements have been performed of pre-prototype optics. These measurements indicate that capillary x-ray optics should be suitable for enhancing contrast and performing beam shaping for matching with digital detectors. Simulation work on a collimating optic has shown good agreement with data and is progressing, which has allowed some design decisions for a suitable optic to be made. A prototype linear detector array has been constructed, along with readout electronics. A single pixel detector has been characterized.







Computer Simulation of X-Ray Capillary Optics for Digital Mammography


Book Description

Polycapillary x-ray optics, arrays of hollow capillary tubes used to guide x-rays by total reflectance, are now being used in increasing numbers of applications, such as materials analysis, microelectronics manufacturing, x-ray astronomy and medical imaging. Because each optic contains hundreds of thousands of precisely shaped and located hollow channels, it is desirable to assess the feasibility of a variety of capillary geometries for a new application without physically constructing the optic. This assessment requires increasingly sophisticated modeling capability as new applications with more stringent requirements are developed. Previous analysis has shown that high-energy applications such as hard x-ray astronomy and medical imaging are particularly sensitive to optic profile errors such as channel waviness. A more physical model for surface waviness has been developed and included in optics simulations. The results are compared to measured data and to the results of other numerical simulation programs. Directed digital mammography can avail itself the advantages of digital processing, including tolerance to under- and over-exposure and image enhancement. In addition, a new technology, polycapillary optics, has been shown to produce clearer image by increasing contrast and resolution. Capillary optics, consisting a array of hollow glass tubes, is a relatively new technology for controlling x-ray beams. Thousands of individual capillary fiber can be strung together to form a multifiber optic. These arrays of curve polycapillary fiber can be used to focus, collimate, and filter x-ray radiation. A number of borrosilicate glass capillary fibers have been measured and simulated in the energy range 10-80 keV. The result shown potential for mammography applications, with transmission of 70% at 20 keV.







Measurements of X-Ray Capillary Optics for Digital Mammography


Book Description

Results of extensive mammography screenings have shown the need for detection of breast cancer at earlier and more curable stages to have any significant impact on the mortality rate. While new imaging technologies for breast cancer diagnosis like magnetic resonance imaging, breast ultrasound and breast specific positron emission tomography are being developed, x%ray imaging continues to function as a convenient and economical choice for early detection.







Medical Imaging


Book Description




Measurements of X-Ray Capillary Optics for Digital Mammography


Book Description

X-ray capillary optics present great potential in designing a mammographic imaging system with high resolution, enhanced contrast, a high dynamic range and a low absorbed dose to the patient. Well engineered optics can collimate, focus and filter x-rays and can magnify images or demagnify images to mate them to a direct x-ray detector. Measurements on two collimating prototypes as pre-patient optics and two linearly tapered optics as post-patient "scatter-rejection" devices are reported here. Preliminary scatter fraction measurements demonstrate an excellent ability to reject Compton scattered photons, implying enhanced contrast in medical imaging systems.