Nano-Biomaterials For Ophthalmic Drug Delivery


Book Description

This consolidated reference book addresses the various aspects of nano biomaterials used in ophthalmic drug delivery, including their characterization, interactions with ophthalmic system and applications in treatments of the ophthalmic diseases and disorders. In the last decade, a significant growth in polymer sciences, nanotechnology and biotechnology has resulted in the development of new nano- and bioengineered nano-bio-materials. These are extensively explored as drug delivery carriers as well as for implantable devices and scaffolds. At the interface between nanomaterials and biological systems, the organic and synthetic worlds merge into a new science concerned with the safe use of nanotechnology and nano material design for biological applications. For this field to evolve, there is a need to understand the dynamic forces and molecular components that shape these interactions. While it is impossible to describe with certainty all the bio physicochemical interactions at play at the interface, we are at a point where the pockets of assembled knowledge are providing a conceptual framework to guide this exploration, and review the impact on future product development. The book is intended as a valuable resource for academics and pharmaceutical scientists working in the field of polymers, polymers materials for drug delivery, drug delivery systems and ophthalmic drug delivery systems, in addition to medical and health care professionals in these areas.




Ocular Drug Delivery Systems


Book Description

Drug discovery for ocular diseases has taken great strides in the last two decades. From cornea to choroid, new drugs have been formulated to address a great variety of ocular diseases. Yet without good drug delivery systems, these drugs are less effective than they might be or could even cause serious side effects. Ocular Drug Delivery Systems: Ba




Nanotechnology in Ophthalmology


Book Description

**Selected for Doody's Core TitlesĀ® 2024 in Ophthalmology**Nanotechnology in Ophthalmology is a comprehensive and up-to-date reference on the role and applications of nanotechnology in ophthalmology, from drug delivery and treatment of ocular diseases to toxicity issues. Written by experts from the nanotechnology, ophthalmology, and pharmacology fields, this book has a unique, broad and diverse scope, including chapters on nanosensor-based diagnostic tools, delivery of nanobiomaterials, implantable materials and devices, delivery of nanobiomaterials, nanotechnology for medical and surgical treatment, regenerative medicine, and more. This book provides a valuable reference to researchers working in the areas of ophthalmology, nanoscience and pharmacology, and clinical fellows who are interested in nanoophthalmology as a reference for their practice and research. - Provides a comprehensive review of the literature in the area of nanoophthalmology - Discusses regenerative medicine, drug delivery, imaging, and medical device applications - Analyzes treatment strategies for emerging and multidrug-resistant ocular pathogens




Ocular Drug Delivery: Advances, Challenges and Applications


Book Description

The eye is a computerized system that has been designed for self-defense, and these defense mechanisms create challenges in administration of medications to the eye. Therefore, ocular drug delivery has been a major challenge to drug delivery researchers. There are on-going studies, in search of treatment especially for the diseases affecting the posterior segment of the eye. This book gives and overview of the background of ocular drug delivery and is unique for pharmacists, medical practitioners, students and drug delivery researchers.




Drug Delivery for the Retina and Posterior Segment Disease


Book Description

This book addresses the issues relating to a wide variety of ocular diseases from which millions of people suffer. Long-term challenges include visual impairment and ocular blindness. Certain ocular diseases are quite rare, whereas others, such as cataracts, age-related macular degeneration (AMD), and glaucoma, are very common, especially in the aging population. A rapid expansion of new technologies in ocular drug delivery and new drug candidates, including biologics, to treat these challenging diseases in the retina and posterior segments of the eye have recently emerged. These approaches are necessary because the eye has many unique barriers to drug delivery. Thus, this timely reference Drug Delivery for the Retina and Posterior Segment Disease compiles and analyzes recent advances in the research and development of drug delivery systems for retina and posterior segment diseases of the eye, with an emphasis on the use of implantable devices, iontophoresis as well as micro- and nanoparticles.




Emerging Trends in Nanomedicine


Book Description

This book illustrates the significance of nanotechnology in the delivery of anticancer and antimicrobial drugs, biomimetic technologies, tissue engineering, sensing, diagnostics, and artificial enzymes. It first briefly discusses the use of nanotechnology for the delivery of anticancer medications, and the concept and applications of catalytically active nanomaterial-based artificial enzymes for sensing and diagnostic applications. It then explores the use of silver nanoparticle-based novel antimicrobials, and comprehensively reviews the role of nanomaterials in developing biomedical implants and tissue engineering applications. Lastly, it offers a detailed description of nanotherapeutics for combating human protozoan parasitic infections. Cutting across the disciplines, this book serves as a guide for researchers and scientists in biotechnology, medical science and material science.




Oxford Handbook of Ophthalmology


Book Description

Fully revised and updated throughout, the fourth edition of the Oxford Handbook of Ophthalmology now includes free access to the ophthalmic online media bank, a selection of high-quality clinical images and videos for a wide breadth of key ophthalmic diseases. Clear, concise, and practical, this handbook provides immediate access to the detailed clinical information you need, in casualty, clinic, theatre, and on the wards. The core of the book comprises a systematic synopsis of ophthalmic disease directed towards diagnosis, interim assessment, and ongoing management. Assessment boxes for common clinical conditions and algorithms for important clinical presentations illustrate this practical approach. The information is easily accessible, presented in a clear format with areas of importance highlighted. Key sections for the trainee include: Clinical Skills, Aids to Diagnosis, Investigations and their Interpretation, Perioperative Care, Theatre Notes and Therapeutics. The wider practise of eye-care is supported by expanded chapters on Refractive Ophthalmology, Vision in Context, Evidence Based Ophthalmology and Resources for Ophthalmologists. Now including newer treatments across a range of specialities such as SMILE, gene-therapy and retinal prostheses, as well as greater emphasis on the evidence underlying current clinical practice and guidelines, this handbook has never been more essential for all those working in eye-care. Whether you want to learn about patient-reported outcomes, identify a surgical instrument, interpret a statistical test, or diagnose and treat ophthalmic emergencies, you will find it here. Whatever your role in caring for patients with eye disease: ophthalmologist, optometrist, orthoptist, ophthalmic nurse, or other health profession - discover for yourself why this handbook has become the 'go-to' resource for tens of thousands of eye-care professionals around the world.




Nanotechnology in Dermatology


Book Description

Nanotechnology in Dermatology is the first book of its kind to address all of the important and rapidly growing aspects of nanotechnology as it relates to dermatology. In the last few years there has been an explosion in research and development for products and devices related to nanotechnology, including numerous applications for consumers, physicians, patients, and industry. Applications are underway in medicine and dermatology for the early detection, diagnosis, and targeted therapy of disease, and nanodesigned materials and devices are expected to be faster, smaller, more powerful, more efficient, and more versatile than their traditional counterparts. Written by experts working in this exciting field, Nanotechnology in Dermatology specifically addresses nanotechnology in consumer skin care products, in the diagnosis of skin disease, in the treatment of skin disease, and the overall safety of nanotechnology. The book also discusses future trends of this ever-growing and changing field, providing dermatologists, pharmaceutical companies, and consumer cosmetics companies with a clear understanding of the advantages and challenges of nanotechnology today.




Nanomedicine and Cancer Therapies


Book Description

Nanotechnology has the power to radically change the way cancer is diagnosed, imaged, and treated. The holistic approach to cancer involves noninvasive procedures that emphasize restoring the health of human energy fields. Presenting a wealth of information and research about the most potent cancer healing therapies, this forward-thinking book explores how nanomedicine, holistic medicine, and other cancer therapies play important roles in treatment of this disease. Topics include nanobiotechnology for antibacterial therapy and diagnosis, mitochondrial dysfunction and cancer, antioxidants and combinatorial therapies, and optical and mechanical investigations of nanostructures for biomolecular detection.




Fundamentals of Drug Delivery


Book Description

A comprehensive guide to the current research, major challenges, and future prospects of controlled drug delivery systems Controlled drug delivery has the potential to significantly improve therapeutic outcomes, increase clinical benefits, and enhance the safety of drugs in a wide range of diseases and health conditions. Fundamentals of Drug Delivery provides comprehensive and up-to-date coverage of the essential principles and processes of modern controlled drug delivery systems. Featuring contributions by respected researchers, clinicians, and pharmaceutical industry professionals, this edited volume reviews the latest research in the field and addresses the many issues central to the development of effective, controlled drug delivery. Divided in three parts, the book begins by introducing the concept of drug delivery and discussing both challenges and opportunities within the rapidly evolving field. The second section presents an in-depth critique of the common administration routes for controlled drug delivery, including delivery through skin, the lungs, and via ocular, nasal, and otic routes. The concluding section summarizes the current state of the field and examines specific issues in drug delivery and advanced delivery technologies, such as the use of nanotechnology in dermal drug delivery and advanced drug delivery systems for biologics. This authoritative resource: Covers each main stage of the drug development process, including selecting pharmaceutical candidates and evaluating their physicochemical characteristics Describes the role and application of mathematical modelling and the influence of drug transporters in pharmacokinetics and drug disposition Details the physiology and barriers to drug delivery for each administration route Presents a historical perspective and a look into the possible future of advanced drug delivery systems Explores nanotechnology and cell-mediated drug delivery, including applications for targeted delivery and toxicological and safety issues Includes comprehensive references and links to the primary literature Edited by a team of of internationally-recognized experts, Fundamentals of Drug Delivery is essential reading for researchers, industrial scientists, and advanced students in all areas of drug delivery including pharmaceutics, pharmaceutical sciences, biomedical engineering, polymer and materials science, and chemical and biochemical engineering.