Author : Xiaoheng Liu
Publisher : Frontiers Media SA
Page : 165 pages
File Size : 25,13 MB
Release : 2022-10-06
Category : Science
ISBN : 2832501621
Author : Junjie Xiao
Publisher : Springer
Page : 300 pages
File Size : 22,72 MB
Release : 2017-09-19
Category : Science
ISBN : 9811043973
The book provides and intensive overview on exosomes in cardiovascular diseases, its potential as biomarkers, as well as pathological and therapeutic effects. It firstly describes the general aspects of exosomes including the definition, formation and secretion of exosomes and highlight their roles as biomarkers and pathological and therapeutic effects in cardiovascular diseases as well. Secondly, basic aspects of exosomes including the purification methods of exosomes, exosomes content, and functional roles of the cardiovascular exosomes are summarized. Thirdly, exosomes as biomarkers of cardiovascular diseases are overviewed including their roles in diagnosis, prognosis and reaction to therapy. Fourthly, pathological effects of exosomes and therapeutic effects of exosomes are highlighted. Finally, future prospects of exosomes in cardiovascular research would be provided. This is an essential reference for researchers working in cell biology and regeneration, as well as clinicians such as cardiologist.
Author : Sara Mole
Publisher : OUP Oxford
Page : 772 pages
File Size : 11,16 MB
Release : 2011-03-10
Category : Medical
ISBN : 019101558X
The neuronal ceroid lipofuscinoses are an extremely rare group of inherited neurodegenerative diseases that primarily affect children. Core symptoms of these conditions typically include epilepsy, cognitive decline and visual failure. These diseases are so rare that professionals who come into contact with them need a consultative reference work that enables them to become expert, or identify who to contact for more details. Fully updated and revised, this second edition continues to be the definitive volume on this devastating group of disorders. Written by an international collection of authorities in the field, it provides invaluable advice on their diagnosis, patient care, and new treatments that are available. This new edition of the definitive reference text on the neuronal ceroid lipofuscinoses will prove useful for clinicians, family physicians, research scientists, diagnostic laboratories, families affected by the disease as well as by workers in industry planning translational research.
Author : Sikha Saha
Publisher : Frontiers Media SA
Page : 317 pages
File Size : 18,27 MB
Release : 2020-01-30
Category :
ISBN : 2889634426
Author : Jamie Bernard
Publisher : Frontiers Media SA
Page : 88 pages
File Size : 48,16 MB
Release : 2024-10-18
Category : Medical
ISBN : 2832555683
The best way to reduce the overall cancer burden is to prevent cancer through a healthy lifestyle, pharmacological strategies, or decreased exposure to environmental carcinogens. Molecular chemical carcinogenesis, identification and evaluation of carcinogenicity hazards, and precision prevention drug discovery have highlighted key cellular, genetic, and epigenetic mechanisms of carcinogenesis that can inform prevention strategies on multiple levels. In this Research Topic, we propose to generate a collection of articles that discuss the main and newly-explored cellular, genetic, and epigenetic targets for cancer prevention, including the immune system. We aim to gain an in-depth understanding of cancer prevention from the molecular to the epidemiological consensus. In particular, these articles will focus on identified mechanisms in tumor initiation, promotion, and malignant transformation for precision prevention and environmental health.
Author : William B. Coleman
Publisher : Academic Press
Page : 636 pages
File Size : 38,11 MB
Release : 2019-11-23
Category : Medical
ISBN : 0128132582
Essential Concepts in Molecular Pathology, Second Edition, offers an introduction to molecular genetics and the "molecular" aspects of human disease. The book illustrates how pathologists harness their understanding of these entities to develop new diagnostics and treatments for various human diseases. This new edition offers pathology, genetics residents, and molecular pathology fellows an advanced understanding of the molecular mechanisms of disease that goes beyond what they learned in medical and graduate school. By bridging molecular concepts of pathogenesis to the clinical expression of disease in cell, tissue and organ, this fully updated, introductory reference provides the background necessary for an understanding of today's advances in pathology and medicine. - Explains the practice of "molecular medicine" and the translational aspects of molecular pathology, including molecular diagnostics, molecular assessment and personalized medicine - Orients non-pathologists on what pathologists look for and how they interpret their observational findings based on histopathology - Provides the reader with what is missing from most targeted introductions to pathology—the cell biology behind pathophysiology
Author : Águeda González Rodríguez
Publisher : Frontiers Media SA
Page : 223 pages
File Size : 12,77 MB
Release : 2022-01-07
Category : Medical
ISBN : 288971988X
Author : Lawrence R. Edelstein
Publisher : Academic Press
Page : 550 pages
File Size : 48,40 MB
Release : 2019-10-16
Category : Science
ISBN : 0128160543
Exosomes: A Clinical Compendium is a comprehensive and authoritative account of exosomes in the context of biomarkers, diagnostics, and therapeutics across a wide spectrum of medical disciplines, as well as their role in cell-cell communication. It is intended to serve as a reference source for clinicians, physicians, and research scientists who wish to gain insight into the most recent advances in this rapidly growing field. The exosome revolution may well be the greatest advance in physiology and medicine since antibiotics. The discovery of their epigenetic role in intercellular signaling in virtually all tissues is a major breakthrough in our understanding of how cells function. - Provides readers with a broad and timely overview of exosomes in health and disease, closing with a thought-provoking chapter on transgenerational inheritance, Darwin and Lamarck. - Summarizes the most recent laboratory and clinical findings on exosomes across numerous medical disciplines, thereby offering readers a broad-ranging and solid foundation for prospective investigative efforts - Twenty-one chapters authored by a global team of peer-acknowledged experts, each representing a key medical disciplineProvides readers with a broad and timely overview of exosomes in health and disease, closing
Author : Dennis V. Cokkinos
Publisher : Springer
Page : 609 pages
File Size : 34,46 MB
Release : 2014-11-06
Category : Medical
ISBN : 3319087983
The term “Translational Research” reflects today’s integration of basic research (“bench”) findings with the clinical practice of medicine, and in a wider scope the application of results from the individual patient (“bedside”) to entire populations for the improvement of public health. This book offers future researchers a stimulus in many aspects of cardiovascular research, so as to promote their interest in future fields of cardiovascular disease, diagnosis and treatment. Introduction to Translational Cardiovascular Research discusses the fundamental and important aspects of the topic. It describes the renin-angiotensin-aldosterone system, the beta adrenergic receptors and the hypothalamic-pituitary-adrenal axis, while covering genetic polymorphisms both generally and specifically as regards the vascular endothelium and the use of microRNAs. As such, this book will be relevant to young physicians, nurses and other scientists engaged in the clinical cardiovascular field who want to added research-oriented dimension to their efforts towards better understanding and practicing of medicine. It also aims to attract young basic researchers who want to develop a better comprehension of the organism as a whole, man or animal, that they are investigating.
Author : Yaoliang Tang
Publisher : Academic Press
Page : 287 pages
File Size : 14,31 MB
Release : 2015-09-02
Category : Science
ISBN : 0128004975
Mesenchymal stem cell-derived exosomes are at the forefront of research in two of the most high profile and funded scientific areas – cardiovascular research and stem cells. Mesenchymal Stem Cell Derived Exosomes provides insight into the biofunction and molecular mechanisms, practical tools for research, and a look toward the clinical applications of this exciting phenomenon which is emerging as an effective diagnostic. Primarily focused on the cardiovascular applications where there have been the greatest advancements toward the clinic, this is the first compendium for clinical and biomedical researchers who are interested in integrating MSC-derived exosomes as a diagnostic and therapeutic tool. - Introduces the MSC-exosome mediated cell-cell communication - Covers the major functional benefits in current MSC-derived exosome studies - Discusses strategies for the use of MSC-derived exosomes in cardiovascular therapies
