Author : Jérôme Paggetti
Publisher : Frontiers Media SA
Page : 164 pages
File Size : 33,88 MB
Release : 2022-01-31
Category : Medical
ISBN : 2889742415
Author : Jérôme Paggetti
Publisher : Frontiers Media SA
Page : 127 pages
File Size : 23,63 MB
Release : 2022-06-23
Category : Medical
ISBN : 2889742075
Author : Tomohiro Kurosaki
Publisher : Springer
Page : 233 pages
File Size : 27,87 MB
Release : 2015-12-26
Category : Medical
ISBN : 3319261339
This volume details our current understanding of the architecture and signaling capabilities of the B cell antigen receptor (BCR) in health and disease. The first chapters review new insights into the assembly of BCR components and their organization on the cell surface. Subsequent contributions focus on the molecular interactions that connect the BCR with major intracellular signaling pathways such as Ca2+ mobilization, membrane phospholipid metabolism, nuclear translocation of NF-kB or the activation of Bruton’s Tyrosine Kinase and MAP kinases. These elements orchestrate cytoplasmic and nuclear responses as well as cytoskeleton dynamics for antigen internalization. Furthermore, a key mechanism of how B cells remember their cognate antigen is discussed in detail. Altogether, the discoveries presented provide a better understanding of B cell biology and help to explain some B cell-mediated pathogenicities, like autoimmune phenomena or the formation of B cell tumors, while also paving the way for eventually combating these diseases.
Author : Jérôme Paggetti
Publisher : Frontiers Media SA
Page : 191 pages
File Size : 50,91 MB
Release : 2022-03-02
Category : Medical
ISBN : 2889742067
Topic Editor MS received funding from Bayer AG.
Author : Tasuku Honjo
Publisher : Academic Press
Page : 0 pages
File Size : 25,22 MB
Release : 2014-12-22
Category : Science
ISBN : 9780123979339
Molecular Biology of B Cells, Second Edition is a comprehensive reference to how B cells are generated, selected, activated and engaged in antibody production. All of these developmental and stimulatory processes are described in molecular, immunological, and genetic terms to give a clear understanding of complex phenotypes. Molecular Biology of B Cells, Second Edition offers an integrated view of all aspects of B cells to produce a normal immune response as a constant, and the molecular basis of numerous diseases due to B cell abnormality. The new edition continues its success with updated research on microRNAs in B cell development and immunity, new developments in understanding lymphoma biology, and therapeutic targeting of B cells for clinical application. With updated research and continued comprehensive coverage of all aspects of B cell biology, Molecular Biology of B Cells, Second Edition is the definitive resource, vital for researchers across molecular biology, immunology and genetics.
Author : Alecsandru Ioan Baba
Publisher :
Page : 787 pages
File Size : 15,54 MB
Release : 2007
Category : Electronic books
ISBN : 9789732714577
Author : Marita Bosticardo
Publisher : Frontiers Media SA
Page : 177 pages
File Size : 32,79 MB
Release : 2021-09-30
Category : Medical
ISBN : 2889714497
Author :
Publisher : Academic Press
Page : 2972 pages
File Size : 31,26 MB
Release : 2015-08-07
Category : Science
ISBN : 0123947960
The Encyclopedia of Cell Biology, Four Volume Set offers a broad overview of cell biology, offering reputable, foundational content for researchers and students across the biological and medical sciences. This important work includes 285 articles from domain experts covering every aspect of cell biology, with fully annotated figures, abundant illustrations, videos, and references for further reading. Each entry is built with a layered approach to the content, providing basic information for those new to the area and more detailed material for the more experienced researcher. With authored contributions by experts in the field, the Encyclopedia of Cell Biology provides a fully cross-referenced, one-stop resource for students, researchers, and teaching faculty across the biological and medical sciences. Fully annotated color images and videos for full comprehension of concepts, with layered content for readers from different levels of experience Includes information on cytokinesis, cell biology, cell mechanics, cytoskeleton dynamics, stem cells, prokaryotic cell biology, RNA biology, aging, cell growth, cell Injury, and more In-depth linking to Academic Press/Elsevier content and additional links to outside websites and resources for further reading A one-stop resource for students, researchers, and teaching faculty across the biological and medical sciences
Author :
Publisher :
Page : 0 pages
File Size : 40,99 MB
Release : 2002
Category : Cells
ISBN : 9780815332183
Author : Marie-Caroline Dieu-Nosjean
Publisher : Humana Press
Page : 289 pages
File Size : 40,28 MB
Release : 2018-09-05
Category : Medical
ISBN : 9781493987085
This volume explores the various methods used to study tertiary lymphoid structures (TLS) in pathological situations. Pre-clinical models are also discussed in detail to show how TLS structure, development, and maintenance can be targeted and studied in vivo. The chapters in this book cover topics such as humans and mice; strategies to quantify TLS in order to use it in stained tissue sections; classifying a gene signature form fixed and paraffin-embedded tissues; and development of murine inflammatory models to help look at TLS in the context of infection or malignancy. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and thorough, Tertiary Lymphoid Structures: Methods and Protocols is a valuable resource that increases the reader’s knowledge on immune functions and how they will pave the way to future therapeutic applications.
