Octacalcium Phosphate Biomaterials


Book Description

Octacalcium Phosphate Biomaterials: Past, Present and Future is a comprehensive study of octacalcium phosphate (OCP), a next generation biomaterial for bone regeneration. By focusing both on fundamental research and the use of OCP as a scaffold material, this book explores its potential to deliver improved clinical results. Early chapters in the book discuss OCP's effects on bone cell activity, cellular interactions and their role in bone formation, repair and replacement. Later chapters cover topics such as drug delivery, synthesis methodologies and future analysis techniques. This will be an invaluable and unique resource for researchers, clinicians, students and industrialists in the area of orthopedics and dentistry. OCP is known to be a pre-cursor to hydroxyapatite in the human biomineralization process that forms bone and tooth enamel. Research studies that have emerged in recent years suggest OCP's tremendous potential as a bioactive material. - Contains comprehensive, up-to-date information on the basic science, including physical, chemical and biological properties - Presents the clinical potential of octacalcium phosphate biomaterials - Provides a reference point for new research and increased activity in the area of next generation smarter biomaterials for hard tissue repair and regeneration




Octacalcium Phosphate


Book Description

The chemistry, structure and biological importance of octacalcium phosphate (OCP) are thoroughly discussed in this volume, which covers a wide scope of topics relevant to the field of calcium phosphates in general. The first chapter reviews the structures of OCP and other important calcium phosphates. It is followed by a description of the mimicry of OCP growth in vivo using in vitro model systems and an extensive review of OCP in biological systems. The remarkable ability of OCP to incorporate biologically relevant organic carboxylates into its structure is also discussed, along with the solubility and surface properties of calcium phosphate salts, and amorphous calcium phosphate and its relationship to OCP. The last chapter centers on the emerging technology of calcium phosphate cements as bone defect repair materials. The book provides in-depth, up-to-date information to all scientists studying calcium phosphate chemistry, biomineralization, pathological calcification, dental caries, biomaterials, and recovery of environmental phosphorus.




Calcium Orthophosphates


Book Description

Due to a great chemical similarity with the biological calcified tissues, many calcium orthophosphates possess remarkable biocompatibility and bioactivity. Materials scientists use this property extensively to construct artificial bone grafts that are either entirely made of or only surface-coated with the biologically relevant calcium orthophospha




Interface Oral Health Science 2016


Book Description

This volume broadens understanding of dentistry and promotes interdisciplinary research across a wide range of related fields, based on the symposium entitled "Innovative Research for Biosis-Abiosis Intelligent Interface 2016". It aims to create highly functional and autonomic intelligent interface by combining highly functional interface science with the technology of an evaluation and a control at the interface, with the various topics of biomaterials, innovation for oral science and application, regenerative oral science, and medical engineering. Since 2002, the Tohoku University Graduate School of Dentistry has hosted "Interface Oral Health Science" several times as the main theme of dental research in the twenty-first century, and this is the sixth proceedings of the symposiums following the ones in 2005, 2007, 2009, 2011, and 2014.This book benefits not only dental scientists but also other health scientists including medical physicians and pharmacologists, material scientists, engineers, and any scientist who is involved in variety of disciplines. This work was published by Saint Philip Street Press pursuant to a Creative Commons license permitting commercial use. All rights not granted by the work's license are retained by the author or authors.




Structure and Chemistry of the Apatites and Other Calcium Orthophosphates


Book Description

The apatites and related calcium phosphates have been of considerable interest to biologists, mineralogists, and inorganic and industrial chemists for many years. This book contains a detailed description of the structures and structural interrelationships of the calcium orthophosphates, including the apatites. Their preparation, crystal growth and dissolution, chemical reactions including thermal decomposition, IR, Raman and NMR spectra and various physical properties are discussed. Apatites other than those containing calcium and phosphorus are included. Synthetic, mineral and biological carbonate apatites are also considered. A wide, but critical coverage of the literature is given, which includes a substantial amount not written in English. Research from many disciplines is included which results in a comprehensive compilation of recent work.




Hydroxyapatite (HAp) for Biomedical Applications


Book Description

Hydroxyapatite in the form of hydroxycarbonate apatite is the principal mineral component of bone tissue in mammals. In Bioceramics, it is classed as a bioactive material, which means bone tissue grows directly on it when placed in apposition without intervening fibrous tissue. Hydroxyapatite is hence commonly used as bone grafts, fillers and as coatings for metal implants. This important book provides an overview of the most recent research and developments involving hydroxyapatite as a key material in medicine and its application. - Reviews the important properties of hydroxyapatite as a biomaterial - Considers a range of specific forms of the material and their advantages - Reviews a range of specific medical applications for this important material




Bone graft substitutes


Book Description




Bioceramics: For Materials Science and Engineering


Book Description

Bioceramics: For Materials Science and Engineering provides a great working knowledge on the field of biomaterials, including the interaction of biomaterials with their biological surroundings. The book discussees the biomedical applications of materials, the standpoint of biomedical professionals, and a real-world assessment of the academic research in the field. It addresses the types of bioceramics currently available, their structure and fundamental properties, and their most important applications. Users will find this to be the only book to cover all these aspects. - Acts as the only introductory reference on bioceramics that covers both the theoretical basics and advanced applications - Includes an overview of the key applications of bioceramics in orthopedics, dentistry and tissue engineering - Uses case studies to build understanding and enable innovation




Developments and Applications of Calcium Phosphate Bone Cements


Book Description

This book presents a state-of-the-art review of the latest advances in developing calcium- phosphate bone cements and their applications. It covers the synthesis methods, characterization approaches, material modification and novel binders, as well as the fabrication technologies of calcium-phosphate-based biomaterials in regenerative medicine and their clinical applications. It also highlights methodologies for fabricating scaffolds, biofunctional surfaces/interfaces and subsequently modulating the host response to implantable/injectable materials, and integrates a series of discussions and insights into calcium-phosphate cements and constructs in bone regenerative medicine. As such, the book not only covers the fundamentals but also opens new avenues for meeting future challenges in research and clinical applications.




Hydroxyapatite and Related Materials


Book Description

Audience Applied biomathematicians, orthopedists, clinical orthopedists.