OECD Guidelines for the Testing of Chemicals / OECD Series on Testing and Assessment Guidance Document on the Use of the Harmonised System for the Classification of Chemicals which are Hazardous for the Aquatic Environment


Book Description

This document provides a description of a Harmonised System for the Classification of Chemicals which are Hazardous for the Aquatic Environment and guidance to how the system will work.




OECD Guidelines for the Testing of Chemicals / OECD Series on Testing and Assessment Harmonised Integrated Classification System for Human Health and Environmental Hazards of Chemical Substances and Mixtures


Book Description

This document sets out the objectives, organisational context, and plan for a Harmonised Integrated Classification System for Human Health and Environmental Hazards of Chemical Substances and Mixtures.




OECD Series on Testing and Assessment Guidance Document on Good In Vitro Method Practices (GIVIMP)


Book Description

In the past several decades, there has been a substantial increase in the availability of in vitro test methods for evaluating chemical safety in an international regulatory context. To foster confidence in in vitro alternatives to animal testing, the test methods and conditions under which ...




OECD Guidelines for the Testing of Chemicals, Section 2 Test No. 231: Amphibian Metamorphosis Assay


Book Description

This Test Guideline describes an amphibian metamorphosis assay intended to screen substances which may interfere with the normal functioning of the hypothalamo-pituitary-thyroid axis. The assay was validated with the species Xenopus laevis, which is ...




OECD Guidelines for the Testing of Chemicals, Section 2 Test No. 241: The Larval Amphibian Growth and Development Assay (LAGDA)


Book Description

This Test Guideline describes the Medaka Extended One Generation Test (MEOGRT), which exposes fish over multiple generations to give data relevant to ecological hazard and risk assessment of chemicals, including suspected endocrine disrupting chemicals (EDCs). Exposure in the MEOGRT starts with ...







OECD Guidelines for the Testing of Chemicals, Section 2 Test No. 210: Fish, Early-life Stage Toxicity Test


Book Description

The test method described in this Test Guideline, is intended to define the lethal and sub-lethal effects of chemicals on the early life stages of the species tested. The early-life stages of fish are exposed to five concentrations of the test ...