Optimizing the Management of Fertility in Women over 40


Book Description

This book offers successful strategies for maximizing the live-birth rate, limiting risk for women trying to conceive later in life.




Clinical Management of Male Infertility


Book Description

This book provides andrologists and other practitioners with reliable, up-to-date information on all aspects of male infertility and is designed to assist in the clinical management of patients. Clear guidance is offered on classification of infertility, sperm analysis interpretation and diagnosis. The full range of types and causes of male infertility are then discussed in depth. Particular attention is devoted to poorly understood conditions such as unexplained couple infertility and idiopathic male infertility, but the roles of diverse disorders, health and lifestyle factors and environmental pollution are also fully explored. Research considered stimulating for the reader is highlighted, reflecting the fascinating and controversial nature of the field. International treatment guidelines are presented and the role of diet and dietary supplements is discussed in view of their increasing importance. Clinicians will find that the book’s straightforward approach ensures that it can be easily and rapidly consulted.




The Demography of Transforming Families


Book Description

This book provides an up-to-date survey on the nature, causes, and patterns of family change. The traditional nuclear family has been replaced by a multiplicity of other forms, as widespread cohabitation, high levels of divorce and union dissolution, rising childlessness, and far below replacement fertility have emerged to an extent never before seen. Theoretical perspectives on this “Second Demographic Transition” are presented, highlighting the dramatic changes in gender roles. New methodological strategies for assessing family dynamics are presented, from multistate models of marriage and divorce combined with fertility to improved techniques for combining census and survey data on the family to a new approach for disentangling age, period, and cohort effects. While the volume emphasizes Western nations, insightful case studies range from analyzing family complexity in cohorts of parents and children in the UK to the impact of interpartner violence on family formation, to the emergence of a “gender war” in South Korea. By providing new insights into where we are today and how we got here, the book will be of value to all those interested in the contemporary family. "Delayed Fertility as a Driver of Fertility Decline?" available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.




Egg Freezing In The 21st Century: A Global Perspective


Book Description

This edited volume covers the development of egg freezing over the last few decades since the pioneering work of Chen in 1986, addressing both the scientific breakthroughs that have occurred and the social and demographic changes that are currently driving an increased demand for 'social' egg freezing and a recognition of the important role of 'medical' egg freezing for women facing potentially sterilizing oncology therapy. It presents the latest research in egg vitrification, methodologies for optimizing laboratory performance and contemporary clinical management of patients seeking oocyte cryopreservation. Audited international data on access, take-up, use and birth outcomes for women undertaking egg freezing are included. The book also discusses the ethical issues related to access and funding and considers how different legal jurisdictions have approached matters such as storage duration, ownership, donation, anonymity and identification. Such wide-ranging contents will bridge the gap between the highly technical laboratory handbooks and the 'popular' tabloid accounts directed at young women considering egg freezing. Drawing on the different approaches to fertility preservation prevailing around the world, with chapters written by leading international experts and edited by Gillian Lockwood, a pioneer of the field whose clinic produced the UK's first 'frozen egg' baby in 2002, Egg Freezing in the 21st Century will have an authoritative and global appeal, and may hopefully encourage a change of attitude in some jurisdictions.




Treatment Strategy for Unexplained Infertility and Recurrent Miscarriage


Book Description

This book offers a highly informative guide to treating unexplained infertility and recurrent miscarriage (RM). In particular, it provides detailed treatment strategies for infertility or RM derived from uterine circumstance such as chronic endometritis and perturbation of endometrial decidualization, as well as maternal immunological rejection of an embryo as semi-allograft. Unexplained infertility refers to those types that cannot be detected by the general screening test. The causes are sometimes detected in the course of treatment with assisted reproductive technology including IVF. However, some unexplained infertility is intractable even after intracytoplasmic sperm injection or repeated implantation of morphologically suitable embryos. Patients with unexplained RM also have a high likelihood of undetectable risk factors of miscarriage. As a result, gynecologists often repeatedly provide these couples with general treatments for infertility and miscarriage or even discontinue treatment because they cannot detect the reason, which places serious financial, physical and mental burdens on the couples affected. This book offers gynecologists essential insights into the pathological condition of unexplained infertility and RM, equipping them to identify it, explain it to patients, and consider further examinations and more aggressive fertility treatments.




Disease Control Priorities, Third Edition (Volume 2)


Book Description

The evaluation of reproductive, maternal, newborn, and child health (RMNCH) by the Disease Control Priorities, Third Edition (DCP3) focuses on maternal conditions, childhood illness, and malnutrition. Specifically, the chapters address acute illness and undernutrition in children, principally under age 5. It also covers maternal mortality, morbidity, stillbirth, and influences to pregnancy and pre-pregnancy. Volume 3 focuses on developments since the publication of DCP2 and will also include the transition to older childhood, in particular, the overlap and commonality with the child development volume. The DCP3 evaluation of these conditions produced three key findings: 1. There is significant difficulty in measuring the burden of key conditions such as unintended pregnancy, unsafe abortion, nonsexually transmitted infections, infertility, and violence against women. 2. Investments in the continuum of care can have significant returns for improved and equitable access, health, poverty, and health systems. 3. There is a large difference in how RMNCH conditions affect different income groups; investments in RMNCH can lessen the disparity in terms of both health and financial risk.







Optimizing Breast Cancer Management


Book Description

This book presents expert opinions on a variety of key topics related to the management of breast cancer, with a focus on the implications of recent advances and research findings for clinical practice. It also explores the controversy regarding mammography screening and reviews the contribution of new imaging modalities. Considerable attention is paid to developments in surgical procedures, including the potential for the safe and effective use of sentinel lymph node dissection alone—even in patients with positive nodes—and to the advantages and contraindications of new radiotherapy techniques. Genetic aspects are discussed in detail, including an assessment of the role of genetic testing and the potential impact of genetic signatures on breast cancer management. New systemic strategies, such as anti-HER2 therapy, endocrine agents, and agents to reverse endocrine resistance, are considered, and the optimal use of chemotherapy for early-stage and advanced-stage disease is addressed. In closing, the book shares important new insights into lifestyle risk factors, risk reduction strategies, and survivor issues, including sexual dysfunction and fertility maintenance.




Practical Problems in Assisted Conception


Book Description

Practical and effective; this book supports challenging clinical and laboratory issues that the IVF practitioner faces all day, every day.




How to Prepare the Egg and Embryo to Maximize IVF Success


Book Description

This comprehensive review of the factors that affect the harvesting and preparation of oocytes and the management of embryos will allow practitioners to make evidence-based decisions for successful IVF. The book reviews and re-considers the value of strategies and outcomes in the management of fertility and conception rates, centred on the production of oocytes, and successful development of the embryo. Authored by leading experts in the field, chapters engage with treatments and strategies that affect the production of oocytes and embryos, optimizing outcomes in the management of female fertility, conception rates, and live births. This vital guide covers controlled ovarian hyperstimulation, the role of AMH in determining ovarian reserve, and primary stimulation agents and the use of adjuncts. Integral for all clinicians and embryologists working in reproductive medicine units, readers are provided with evidence-based, comprehensive advice and review of all factors affecting the management of oocytes and the embryo that are vital for successful IVF cycles.