Peripheral Nerve Disorders


Book Description

Peripheral Nerve Disorders: Pathology and Genetics is a definitive, clinically-oriented guide to the pathology of peripheral nerve disorders. These commonly seen neurological challenges have many causes and accurate diagnosis is often necessary via pathological analysis. New techniques exploiting molecular biological knowledge have opened up new vistas to understanding the pathogenesis of these disorders, and hence their effective management. This new title takes a disease-oriented approach to understanding the pathology of these conditions. It combines classical and contemporary techniques to enable practitioners in neurology and neuropathology to better understanding of the disease processes underlying patients’ presentations and to formulate appropriate management plans. Peripheral Nerve Disorders: Pathology and Genetics is a valuable resource for neurologists, neuropathologists, pathologists, neurobiologists and geneticists.




Diagnosis and Management of Peripheral Nerve Disorders


Book Description

Peripheral neuropathies represent a challenging subject for most physicians. This is an up-to-date, comprehensive, and readable book on peripheral neuropathies that includes concise information on the clinical, electrophysiological, pathological, pathogenic, and treatment aspects of the most important disorders. New molecular and serologic diagnostic tests are discussed. Sections are devoted to nerve and skin biopsy techniques and findings, quantitative sensory and autonomic reflex tests. Case examples are used liberally throughout the text. The editors: Mendell, Kissel, and Cornblath are experienced clinicians that bring complementary knowledge to each of the subjects. Additional authors have been handpicked for specific topics which add to the value of the edition.




Surgical Disorders of the Peripheral Nerves


Book Description

Since the highly praised first edition of Surgical Disorders of the Peripheral Nerves was published in 1998, greater understanding of the the molecular and cellular events which underlie the response of nerves to injury, regeneration and neuropathic pain has been achieved. This second edition has been fully updated in line with new clinical knowledge, and also incorporates the extensive study of thousands of surgical case studies spanning repairs of the supraclavicular plexus in the adult, the birth lesion of the brachial plexus,compound nerve injury and iatrogenous injury. Beginning with the fundamentals of the anatomy and function of the peripheral nervous system, and working its way through various types of injury, operative methods, the regeneration and recovery of nerves, surgical reconstruction, pain, and rehabilitation, this eloquently written work provides the reader with the solid understanding required to successfully perform surgery on the peripheral nervous system. Dr Shelagh Smith, joined by Dr Ravi Knight, has rewritten the chapter Electrodiagnosis. Professor Tara Renton has written a new chapter on injuries to the trigeminal nerve in maxilla-facial and dental work. The drawings, by Mr Philip Wilson, are new. Most of the 700 illustrations are also new. This thorough and authoritative look at the surgical treatment of the peripheral nerves is fully illustrated throughout with exquisite line diagrams and clear, instructive photographs.




Peripheral Nerve Issues after Orthopedic Surgery


Book Description

Peripheral nerve issues are potential sequalae of orthopedic surgery, even after cases in which technically excellent surgery was performed. These injuries can impede the expected recovery of function after the primary surgery. Given the manifold challenges associated with recovery of peripheral nerve injuries, this book is designed as a multidisciplinary guide to the diagnosis, prognostication and treatment of peripheral nerve issues after common orthopedic surgeries. Beginning with an overview of nerve compression, injury and regeneration, as well as a presentation of the current diagnostic and imaging modalities for peripheral nerve injuries, this unique text is organized by anatomic region and by type of procedure performed. Topics covered include shoulder and elbow arthroplasty and arthroscopy, fractures of the hand and wrist, hip preservation surgery, total knee replacement, open surgery of the foot and ankle, lumbosacral myeloradiculopathy, and more. Each chapter is authored by both a subspecialty surgeon who routinely performs the surgeries described and a subspecialized hand/peripheral nerve surgeon with experience in evaluating and treating nerve issues after that particular injury. Emphasis is placed on multidisciplinary team approaches, patient counseling, and technical aspects of surgical treatment. Generously illustrated and written by experts in the field, Peripheral Nerve Issues after Orthopedic Surgery is a truly interdisciplinary resource for orthopedic, plastic, hand and trauma surgeons, physiatrists, trainees, and all professionals evaluating and managing postoperative peripheral nerve issues.




Pathology of Peripheral Nerves


Book Description

This atlas illustrates pathological changes of peripheral nerves covering experimental and human, light and electron microscopic, immunohistochemical, morphometric and moleculargenetic aspects. Basic general pathologic reactions are shown as well as characteristic alterations in a large number of specific diseases affecting the peripheral nervous system (PNS) primarily or secondarily. The 1050 illustrations are of diagnostic significance for those studying peripheral nerves at the miscroscopic or ultrastructural level, and for neurologists, neurosurgeons, neurobiologists, and electrophysiologists trying to understand the underlying structural changes causing the clinical signs and symptoms of a variety of diseases and disorders.




Musculoskeletal Diseases 2021-2024


Book Description

This open access book focuses on imaging of the musculoskeletal diseases. Over the last few years, there have been considerable advances in this area, driven by clinical as well as technological developments. The authors are all internationally renowned experts in their field. They are also excellent teachers, and provide didactically outstanding chapters. The book is disease-oriented and covers all relevant imaging modalities, with particular emphasis on magnetic resonance imaging. Important aspects of pediatric imaging are also included. IDKD books are completely re-written every four years. As a result, they offer a comprehensive review of the state of the art in imaging. The book is clearly structured with learning objectives, abstracts, subheadings, tables and take-home points, supported by design elements to help readers easily navigate through the text. As an IDKD book, it is particularly valuable for general radiologists, radiology residents, and interventional radiologists who want to update their diagnostic knowledge, and for clinicians interested in imaging as it relates to their specialty.




Biopsy Diagnosis of Peripheral Neuropathy


Book Description

Peripheral nerve analysis is a challenging task for pathologists, given the advent of new diagnoses and techniques of analysis and the impact of molecular genetics. This book presents a simple, logical method for constructing a differential diagnosis based on pathology and clinical presentation. It also provides advice on the selection of ancillary molecular, immunohistochemical and genetic techniques to establish a definitive diagnosis. Clear, authoritative guidance is offered on diagnosis of the full range of neuropathies with the aid of a wealth of high-quality color photomicrographs and electron micrographs. The pathologist will benefit greatly from the identification of a variety of artifacts and normal structures occasionally encountered in nerve biopsies that need to be distinguished from specific pathologic alterations. This user-friendly, practical text will be an invaluable aid in achieving the most specific diagnosis possible.




Ultrasonography Diagnosis of Peripheral Nerves


Book Description

As a hot topic in ultrasound medicine, peripheral nerve ultrasound has its wide applications in clinical field. This book firstly introduces the anatomy of peripheral nerves, method and normal sonograms for peripheral nerve scanning. In the following chapters, common and typical cases of peripheral nerves diseases are presented with useful clinical information and relevant data, for example, ultrasound, MRI, clinical operation and pathology results. At the end of each disease, video with detailed explanation of diagnostic procedure and 2-3 bullet points in practical differential diagnosis are included to help readers taking notes. This book will be a valuable reference for physicians in ultrasound, anesthetists, neurologists, pain specialists, and practitioners interested in related field.




Textbook of Peripheral Neuropathy


Book Description

Textbook of Peripheral Neuropathy is a practical but authoritative reference for clinicians in anymedical specialty who are evaluating and treating patients with signs and symptoms of a peripheralneuropathy. Reviewing the full spectrum of clinically significant neuropathies, the book contains chapterson common and rare forms including mononeuropathy in the upper and lower extremities, mononeuritismultiplex, diffuse and symmetric polyneuropathies, brachial and lumbrosacral plexopathies, and spinalroot disordersódisorders that can mimic diffuse and/or focal neuropathies, complicating diagnosis andevaluation. Coverage encompasses both inherited and acquired diseases, including neuropathies arisingfrom physical injury, diabetes, alcoholism, toxins, autoimmune responses, nutritional deficiencies, vascularand metabolic disorders, medication-induced neuropathies, and idiopathic conditions. The textbookprovides an evidence-based approach to testing, differential diagnosis, and treatment, and should serveas a trusted resource for healthcare professionals confronting the many manifestations of peripheralneuropathy in clinical practice. The chapters are written by internationally renowned expert contributors with deep clinical experienceand contain numerous tables, figures, and algorithms providing clear diagnostic and managementguidelines. Boxed Clinical Pearls and Key Points allow for quick access to pertinent information, making evaluation and review easy and rewarding. Features of Textbook of Peripheral Neuropathy Include: ̈ Practical yet comprehensiveóan accessible ìgo-toî reference for clinicians ̈ Covers all clinically relevant peripheral neuropathies ̈ Clinical Pearls and Key Points are set off from the text for quick reference ̈ Contains clear diagnostic and management guidelines from expert contributors ̈ Structured chapters make it easy to find essential point-of-careinformation




Peripheral Nerve Disorders


Book Description

Disorders of the peripheral nervous system (PNS) are the cause of prominent neurological symptoms including weakness, sensory loss, pain and autonomic dysfunction associated with deficits, morbidity and mortality. These disorders may be primary hereditary or cryptogenic neurologic disorders confined to the PNS or part of the pathology of both the central nervous system and the PNS. Most PNS disorders are secondary to other system disorders and may be responsive to treatment of the primary disease. Important advances have been obtained in several areas including molecular genetics, biochemistry, immunology, morphology and physiology that have enhanced our understanding of the causes and consequences of damage to peripheral nerve. Understanding of both these groups of PNS diseases has greatly expanded over recent years and has led to important advances of treatment both to protect and to repair damages of peripheral nerve. This volume provides an overview of the state-of-the-art of examination, diagnosis and treatment of these very diverse disorders and will be of interest to both the research and clinical neuroscience and neurology communities. Covers both hereditary and cryptogenic neurologic disorders Includes advances in the basic science of PNS from molecular genetics, biochemistry, immunology, morphology and physiology Detailed coverage of neuropathy in connective tissue disorders, infectious disorders, metabolic disorders and malignancy