Persistent, Bioaccumulative, and Toxic Chemicals II


Book Description

This work is "aimed at examining persistent, bioaccumulative, toxic chemicals that undergo slow environmental degradation in air, water, and soil, bioaccumulate in fish and other organisms, and exhibit a high degree of toxicity. This volume examines the fate and behavior of these chemicals, and their food chain transfer and exposure. Chapters cover recent research results and reviews related to polychlorinated biphenyls (PCBs), butyltin, toxaphene, dioxin, alpha-hexachlorocyclohexane and mercury."--Publisher.




Persistent, Bioaccumulative, and Toxic (PBT) Chemicals


Book Description

Developed from the efforts of a multiyear, international project examining how persistent, bioaccumulative, and toxic (PBT) chemicals are evaluated and managed, Persistent, Bioaccumulative, and Toxic (PBT) Chemicals: Technical Aspects, Policies, and Practices focuses on improving the processes that govern PBTs. Incorporating science and policy literature—as well as interviews and panel discussions featuring experts from around the world—this book provides you with an international perspective of PBT policies (centering on Europe, Asia, and North America), and reveals major findings and recommendations for improving PBT science, laws, and policies. It includes case studies of specific chemicals, provides an introduction to the overall subject of toxic chemicals, and weighs in on science and policy expansion for PBTs. It also provides summary tables of important PBTs, and discussions on the number of PBTs in commerce, weight of evidence approaches, market deselection, and international management. The text: Assesses the history, current practice, and future of PBT management Considers the roles scientific data, modeling, and conventions play in identifying and regulating PBTs Explores the number of PBTs in commerce and the growing role of weight of evidence (WOE) in the making of PBT determinations Identifies issues that are likely to come up in WOE judgments Examines international, national, subnational, and regional PBT policies Includes a comprehensive and easy-to-understand analysis of PBT science and policy This book reviews the current science, policies, and practices surrounding the regulation of PBTs. It also provides relevant research, recommendations, and suggestions for improving the management and oversight of PBTs.




Persistent, Bioaccumulative, and Toxic Chemicals: Assessment and new chemicals


Book Description

This work is "aimed at examining persistent, bioaccumulative, toxic chemicals that undergo slow environmental degradation in air, water, and soil, bioaccumulate in fish and other organisms, and exhibit a high degree of toxicity. This volume examines the fate and behavior of these chemicals, and their food chain transfer and exposure. Chapters cover recent research results and reviews related to polychlorinated biphenyls (PCBs), butyltin, toxaphene, dioxin, alpha-hexachlorocyclohexane and mercury."--Publisher.







Persistent, Bioaccumulative, and Toxic Chemicals I


Book Description

This is part of a two-book assessment of hydrolase structure/functionrelationships and the means by which these important enzymes can be betterutilized. Each book, Assessment and Emerging New Chemicals and Fate andExposure, will deal with understanding cellulase and hemicellulase action - astrategy based in macromolecular modeling, site-directed mutagenesis, activesite mapping, heterologous expression, and classical kinetic characterization.Information about new cellulase enzymes and systems and trends in the field ofglycosyl hydrolase biochemistry will be examined as well as new crystallographicstructure of important cellulases and methods for improving activity by proteinengineers.




Emerging Contaminants


Book Description

Emerging Contaminants: Anticipating Developments examines the factors that have led "new" environmental contaminants to emerge in the past and combines the lessons learned to anticipate potential new developments. The analyses described in this book originate in multiple disciplines: the science of toxicology; environmental law and regulation; the field of product stewardship; and the social science which explains why ideas take hold. Over a dozen case studies of contaminants that emerged as environmental issues over the last hundred years illustrate crucial points. The results of the analyses in this book support a step-by-step method to assess the potential for a contaminant to emerge, and a framework to apply those conclusions to managing site liabilities. Features: Describes an unprecedented understanding of why contaminants emerge as issues, based on a multidisciplinary analysis Makes abstract concepts tangible, basing analyses on data and illustrating key points with case studies Enables readers to anticipate and prepare to manage future challenges associated with emerging chemicals Presents an analytical framework for companies to assess and manage business risks Written for regulators, policymakers, industry professionals with responsibility for contaminated site management, as well as attorneys, and consultants, this book provides a framework for anticipating the emergence of new contaminants so that the risks–whether to human health and the environment or to a business–can be anticipated and appropriately managed.







Toxicological Risk Assessment of Chemicals


Book Description

Unlike many existing books on toxicology that cover either toxicity of a particular substance or toxicity of chemicals on particular organ systems, Toxicological Risk Assessment of Chemicals: A Practical Guide lays out the principle activities of conducting a toxicological risk assessment, including international approaches and methods for the risk




Monitoring Human Tissues for Toxic Substances


Book Description

The National Human Monitoring Program (NHMP) identifies concentrations of specific chemicals in human tissues, including toxicologic testing and risk assessment determinations. This volume evaluates the current activities of the NHMP; identifies important scientific, technical, and programmatic issues; and makes recommendations regarding the design of the program and use of its products.




Toxic Chemicals


Book Description

Over the past decade, advances in laboratory technology have provided new tools for measuring a broad range of chemicals in human tissues -- tools that can help researchers & health officials assess how much of a chemical has been absorbed in the body & provide more accurate measure. of exposure to relate to potential health risks. This report reviews efforts to collect & use such information at both the state & Federal levels. It: determines the extent to which state & Federal agencies -- in particular, HHS & EPA -- collect human exposure data on potentially harmful chemicals, including data to identify at-risk populations; & identifies the barriers hindering further progress in such efforts.