Photon Counting Detectors for X-ray Imaging


Book Description

This book first provides readers with an introduction to the underlying physics and state-of-the-art application of photon counting detectors for X-ray imaging. The authors explain that a photon-counting imaging detector can realize quantitative analysis because the detector can derive X-ray attenuation information based on the analysis of intensity changes of individual X-ray. To realize this analysis, it is important to consider the physics of an object and detector material. In this book, the authors introduce a novel analytical procedure to create quantitative X-ray images for medical diagnosis.




Spectral, Photon Counting Computed Tomography


Book Description

Spectral, Photon Counting Computed Tomography is a comprehensive cover of the latest developments in the most prevalent imaging modality (x-ray computed tomography (CT)) in its latest incarnation: Spectral, Dual-Energy, and Photon Counting CT. Disadvantages of the conventional single-energy technique used by CT technology are that different materials cannot be distinguished and that the noise is larger. To address these problems, a novel spectral CT concept has been proposed. Spectral Dual-Energy CT (DE-CT) acquires two sets of spectral data, and Spectral Photon Counting CT (PC-CT) detects energy of x-ray photons to reveal additional material information of objects by using novel energy-sensitive, photon-counting detectors. The K-edge imaging may be a gateway for functional or molecular CT. The book covers detectors and electronics, image reconstruction methods, image quality assessments, a simulation tool, nanoparticle contrast agents, and clinical applications for spectral CT.




Photon-Counting Image Sensors


Book Description

This book is a printed edition of the Special Issue "Photon-Counting Image Sensors" that was published in Sensors




Spectral Computed Tomography


Book Description

Computed tomography (CT) is a widely used x-ray scanning technique. In its prominent use as a medical imaging device, CT serves as a workhorse in many clinical settings throughout the world. It provides answers to urgent diagnostic tasks such as oncology tumor staging, acute stroke analysis, or radiation therapy planning. Spectral Computed Tomography provides a concise, practical coverage of this important medical tool. The first chapter considers the main clinical motivations for spectral CT applications. In Chapter 2, the measurement properties of spectral CT systems are described. Chapter 3 provides an overview of the current state of research on spectral CT algorithms. Based on this overview, the technical realization of spectral CT systems is evaluated in Chapter 4. Device approaches such as DSCT, kV switching, and energy-resolving detectors are compared. Finally, Chapter 5 summarizes various algorithms for spectral CT reconstructions and spectral CT image postprocessing, and links these algorithms to clinical use cases




Medical Imaging


Book Description

A must-read for anyone working in electronics in the healthcare sector This one-of-a-kind book addresses state-of-the-art integrated circuit design in the context of medical imaging of the human body. It explores new opportunities in ultrasound, computed tomography (CT), magnetic resonance imaging (MRI), nuclear medicine (PET, SPECT), emerging detector technologies, circuit design techniques, new materials, and innovative system approaches. Divided into four clear parts and with contributions from a panel of international experts, Medical Imaging systematically covers: X-ray imaging and computed tomography–X-ray and CT imaging principles; Active Matrix Flat Panel Imagers (AMFPI) for diagnostic medical imaging applications; photon counting and integrating readout circuits; noise coupling in digital X-ray imaging Nuclear medicine–SPECT and PET imaging principles; low-noise electronics for radiation sensors Ultrasound imaging–Electronics for diagnostic ultrasonic imaging Magnetic resonance imaging–Magnetic resonance imaging principles; MRI technology




Photon Counting Detectors for X-ray Imaging


Book Description

This book first provides readers with an introduction to the underlying physics and state-of-the-art application of photon counting detectors for X-ray imaging. The authors explain that a photon-counting imaging detector can realize quantitative analysis because the detector can derive X-ray attenuation information based on the analysis of intensity changes of individual X-ray. To realize this analysis, it is important to consider the physics of an object and detector material. In this book, the authors introduce a novel analytical procedure to create quantitative X-ray images for medical diagnosis. Provides a detailed explanation of the principle of imaging using an energy integrating detector (EID) which is currently being used as an X-ray imaging detector in medicine; Provides a single-source reference that enables readers to understand photon-counting techniques, including the underlying basic physics, specific physics of the detector, novel analytical procedure and future scope; Includes necessary background information and state-of-the-art applications; Demonstrates procedure using a simulation study and a proto-type imaging detector; Presents information in a manner which makes it easier for readers to reproduce results.




Single-Photon Imaging


Book Description

The acquisition and interpretation of images is a central capability in almost all scientific and technological domains. In particular, the acquisition of electromagnetic radiation, in the form of visible light, UV, infrared, X-ray, etc. is of enormous practical importance. The ultimate sensitivity in electronic imaging is the detection of individual photons. With this book, the first comprehensive review of all aspects of single-photon electronic imaging has been created. Topics include theoretical basics, semiconductor fabrication, single-photon detection principles, imager design and applications of different spectral domains. Today, the solid-state fabrication capabilities for several types of image sensors has advanced to a point, where uncoooled single-photon electronic imaging will soon become a consumer product. This book is giving a specialist ́s view from different domains to the forthcoming “single-photon imaging” revolution. The various aspects of single-photon imaging are treated by internationally renowned, leading scientists and technologists who have all pioneered their respective fields.




Electronics for Radiation Detection


Book Description

There is a growing need to understand and combat potential radiation damage problems in semiconductor devices and circuits. Assessing the billion-dollar market for detection equipment in the context of medical imaging using ionizing radiation, Electronics for Radiation Detection presents valuable information that will help integrated circuit (IC) designers and other electronics professionals take full advantage of the tremendous developments and opportunities associated with this burgeoning field. Assembling contributions from industrial and academic experts, this book— Addresses the state of the art in the design of semiconductor detectors, integrated circuits, and other electronics used in radiation detection Analyzes the main effects of radiation in semiconductor devices and circuits, paying special attention to degradation observed in MOS devices and circuits when they are irradiated Explains how circuits are built to deal with radiation, focusing on practical information about how they are being used, rather than mathematical details Radiation detection is critical in space applications, nuclear physics, semiconductor processing, and medical imaging, as well as security, drug development, and modern silicon processing techniques. The authors discuss new opportunities in these fields and address emerging detector technologies, circuit design techniques, new materials, and innovative system approaches. Aimed at postgraduate researchers and practicing engineers, this book is a must for those serious about improving their understanding of electronics used in radiation detection. The information presented here can help you make optimal use of electronic detection equipment and stimulate further interest in its development, use, and benefits.




Synchrotron Light Sources and Free-Electron Lasers


Book Description

Hardly any other discovery of the nineteenth century did have such an impact on science and technology as Wilhelm Conrad Röntgen’s seminal find of the X-rays. X-ray tubes soon made their way as excellent instruments for numerous applications in medicine, biology, materials science and testing, chemistry and public security. Developing new radiation sources with higher brilliance and much extended spectral range resulted in stunning developments like the electron synchrotron and electron storage ring and the freeelectron laser. This handbook highlights these developments in fifty chapters. The reader is given not only an inside view of exciting science areas but also of design concepts for the most advanced light sources. The theory of synchrotron radiation and of the freeelectron laser, design examples and the technology basis are presented. The handbook presents advanced concepts like seeding and harmonic generation, the booming field of Terahertz radiation sources and upcoming brilliant light sources driven by laser-plasma accelerators. The applications of the most advanced light sources and the advent of nanobeams and fully coherent x-rays allow experiments from which scientists in the past could not even dream. Examples are the diffraction with nanometer resolution, imaging with a full 3D reconstruction of the object from a diffraction pattern, measuring the disorder in liquids with high spatial and temporal resolution. The 20th century was dedicated to the development and improvement of synchrotron light sources with an ever ongoing increase of brilliance. With ultrahigh brilliance sources, the 21st century will be the century of x-ray lasers and their applications. Thus, we are already close to the dream of condensed matter and biophysics: imaging single (macro)molecules and measuring their dynamics on the femtosecond timescale to produce movies with atomic resolution.




Pixel Detectors


Book Description

Pixel detectors are a particularly important class of particle and radiation detection devices. They have an extremely broad spectrum of applications, ranging from high-energy physics to the photo cameras of everyday life. This book is a general purpose introduction into the fundamental principles of pixel detector technology and semiconductor-based hybrid pixel devices. Although these devices were developed for high-energy ionizing particles and radiation beyond visible light, they are finding new applications in many other areas. This book will therefore benefit all scientists and engineers working in any laboratory involved in developing or using particle detection.