Advances in Perinatal Medicine


Book Description

The state of health care isreflected by perinatal and neonatal morbidity and mortality as weIl as by the frequencies of long-term neurological and developmental disorders. Many factors, some without immediately recognizable significance to childbearing and many still unknown, undoubtedly contribute beneficially or adversely to the outcome of pregnancy. Knowledge concerning the impact of such factors on the fetus and survivinginfant iscritical. Confounding analysesofpregnancy outcome, especially these past 2 or 3 decades, are the effects of newly undertaken invasive or inactive therapeutic approaches coupled with the advent of high technology. Many innovations have been introduced without serious efforts to evaluate their impact prospectively and objectively. The consequences of therapeutic misadventures character ized the past; it seems they have been replaced to a degree by some of the complications of applied technology. Examples abound: after overuse of oxygen was recognized to cause retrolental fibroplasia, its restriction led to an increase in both neonatal death rates and neurologic damage in surviving infants. Administration of vitamin K to prevent neonatal hemorrhagic disease, particularly when given in what we now know as excessive dosage, occasionally resulted in kernicterus. Prophy lactic sulfonamide use had a similar end result. More recent is the observation of bronchopulmonary dysplasia as a complication of re spirator therapy for hyaline membrane disease. The decade of the eighties opened with the all-time highest rate of cesarean section in the United States.







Volpe's Neurology of the Newborn E-Book


Book Description

**Selected for Doody's Core Titles® 2024 in Neurology**Stay up to date with today's latest advances in diagnosis and management, as well as the many scientific and technological advances that are revolutionizing neonatal neurology, with the definitive text in the field. Volpe's Neurology of the Newborn, 7th Edition, shares the knowledge and expertise of world authority Dr. Joseph Volpe, who, along with Dr. Terrie E. Inder of Children's Hospital of Orange County and other distinguished editors, brings a wealth of insight to this classic text. Known for its clear, engaging writing style, vibrant, full-color illustrations, and authoritative information throughout, this reference is an indispensable resource for those who provide care for neonates with neurological conditions. - Provides clear, comprehensive coverage of neonatal neurology in Dr. Joseph Volpe's own legendary, readable manner—for a masterful, cohesive source of answers to any question that arises in your practice. - Brings the latest science into the clinical setting, with an emphasis on translating new knowledge to the infant's bedside. - Offers comprehensive updates with summary tables and text to reflect major advances in the study of hemorrhage; new insights into molecular genetics and molecular characterization of brain tumors; significant advances in drugs and the developing nervous system; and much more. - Includes new chapters on fetal neurology which address the importance of understanding and investigating the maternal-fetal origins of neonatal disease, as well as new chapters on neurodevelopmental follow-up, inflammation, and neurology in low-resource settings. - Contains more than 1,000 illustrations: clinical and pathological specimens, key experimental findings, schematics, algorithms, anatomical drawings, and neuroimaging throughout, as well as numerous tables and boxes that synthesize key points. - Any additional digital ancillary content may publish up to 6 weeks following the publication date.










Research in Education


Book Description







Clinical Diagnosis of Mental Disorders


Book Description

For centuries the "treatment" of mentally disturbed individuals was quite simple. They were accused of collusion with evil spirits, hunted, and persecuted. The last "witch" was killed as late as 1782 in Switzerland. Mentally disturbed people did not fare much better even when the witchhunting days were gone. John Christian Reil gave the following description of mental pa tients at the crossroads of the fifteenth and sixteenth centuries: We incarcerate these miserable creatures as if they were criminals in abandoned jails, near to the lairs of owls in barren canyons beyond the city gates, or in damp dungeons of prisons, where never a pitying look of a humanitarian penetrates; and we let them, in chains, rot in their own excrement. Their fetters have eaten off the flesh of their bones, and their emaciated pale faces look expectantly toward the graves which will end their misery and cover up our shamefulness. (1803) The great reforms introduced by Philippe Pinel at Bicetre in 1793 augured the beginning of a new approach. Pinel ascribed the "sick role," and called for compas sion and help. One does not need to know much about those he wants to hurt, but one must know a lot in order to help. Pinel's reform was followed by a rapid develop ment in research of causes, symptoms, and remedies of mental disorders. There are two main prerequisites for planning a treatment strategy.