Power Trial Method


Book Description

The Power Trial Method, Second Edition, a unique, easy-to-read trial skills primer, begins with a simple question about jury trials: Who has the power in the courtroom to decide whether you win or lose? David J.F. Gross and Charles F. Webber, two of the nation's most highly regarded trial lawyers, developed this material to introduce new litigators to the trial process and to reduce the anxiety associated with jury trials by emphasizing key methods of persuasion and presentation.




Power Trial Method


Book Description

The Power Trial Method, Second Edition, a unique, easy-to-read trial skills primer, begins with a simple question about jury trials: Who has the power in the courtroom to decide whether you win or lose? David J.F. Gross and Charles F. Webber, two of the nation's most highly regarded trial lawyers, developed this material to introduce new litigators to the trial process and to reduce the anxiety associated with jury trials by emphasizing key methods of persuasion and presentation.




How Many Subjects?


Book Description

How Many Subjects? is a practical guide to sample size calculations and general principles of cost-effective research. It introduces a simple technique of statistical power analysis which allows researchers to compute approximate sample sizes and power for a wide variety of research designs. Because the same technique is used with only slight modifications for different statistical tests, researchers can easily compare the sample sizes required by different designs and tests to make cost-effective decisions in planning a study. These comparisons, emphasized throughout the book, demonstrate important principles of design, measurement and analysis that are rarely discussed in courses or textbooks.




Small Clinical Trials


Book Description

Clinical trials are used to elucidate the most appropriate preventive, diagnostic, or treatment options for individuals with a given medical condition. Perhaps the most essential feature of a clinical trial is that it aims to use results based on a limited sample of research participants to see if the intervention is safe and effective or if it is comparable to a comparison treatment. Sample size is a crucial component of any clinical trial. A trial with a small number of research participants is more prone to variability and carries a considerable risk of failing to demonstrate the effectiveness of a given intervention when one really is present. This may occur in phase I (safety and pharmacologic profiles), II (pilot efficacy evaluation), and III (extensive assessment of safety and efficacy) trials. Although phase I and II studies may have smaller sample sizes, they usually have adequate statistical power, which is the committee's definition of a "large" trial. Sometimes a trial with eight participants may have adequate statistical power, statistical power being the probability of rejecting the null hypothesis when the hypothesis is false. Small Clinical Trials assesses the current methodologies and the appropriate situations for the conduct of clinical trials with small sample sizes. This report assesses the published literature on various strategies such as (1) meta-analysis to combine disparate information from several studies including Bayesian techniques as in the confidence profile method and (2) other alternatives such as assessing therapeutic results in a single treated population (e.g., astronauts) by sequentially measuring whether the intervention is falling above or below a preestablished probability outcome range and meeting predesigned specifications as opposed to incremental improvement.




Clinical Trial Methodology


Book Description

Now viewed as its own scientific discipline, clinical trial methodology encompasses the methods required for the protection of participants in a clinical trial and the methods necessary to provide a valid inference about the objective of the trial. Drawing from the authors' courses on the subject as well as the first author's more than 30 years wor




Reform and Development of Powers and Functions of China's Criminal Proceedings


Book Description

This book addresses the basic theory of criminal procedure in China, together with recent reforms. Balancing the powers of public security and judicial organs with the rights of individual citizens, it assesses the nature of Chinese criminal proceedings. In the basic theoretical research section, the author, drawing on the latest findings from the legal community, systematically and comprehensively presents the current trends, main research topics and the main problems that should be explored in future research into criminal procedure law in China; further, the author explains the basic thinking behind the revision of criminal procedure law, and the allocation of judicial resources in criminal procedure and criminal justice. The policy, basic theory and operation problems of judicial power, procuratorial power, police power, defense power and judicial reform are subsequently explained and evaluated. The general writing style used is intentionally straightforward, making the book easily accessible for the readers. Based on the author’s substantial working experience in the area of criminal law, it offers a highly intuitive reading experience.




Group Sequential Methods with Applications to Clinical Trials


Book Description

Group sequential methods answer the needs of clinical trial monitoring committees who must assess the data available at an interim analysis. These interim results may provide grounds for terminating the study-effectively reducing costs-or may benefit the general patient population by allowing early dissemination of its findings. Group sequential methods provide a means to balance the ethical and financial advantages of stopping a study early against the risk of an incorrect conclusion. Group Sequential Methods with Applications to Clinical Trials describes group sequential stopping rules designed to reduce average study length and control Type I and II error probabilities. The authors present one-sided and two-sided tests, introduce several families of group sequential tests, and explain how to choose the most appropriate test and interim analysis schedule. Their topics include placebo-controlled randomized trials, bio-equivalence testing, crossover and longitudinal studies, and linear and generalized linear models. Research in group sequential analysis has progressed rapidly over the past 20 years. Group Sequential Methods with Applications to Clinical Trials surveys and extends current methods for planning and conducting interim analyses. It provides straightforward descriptions of group sequential hypothesis tests in a form suited for direct application to a wide variety of clinical trials. Medical statisticians engaged in any investigations planned with interim analyses will find this book a useful and important tool.




The First 20 Hours


Book Description

Forget the 10,000 hour rule— what if it’s possible to learn the basics of any new skill in 20 hours or less? Take a moment to consider how many things you want to learn to do. What’s on your list? What’s holding you back from getting started? Are you worried about the time and effort it takes to acquire new skills—time you don’t have and effort you can’t spare? Research suggests it takes 10,000 hours to develop a new skill. In this nonstop world when will you ever find that much time and energy? To make matters worse, the early hours of prac­ticing something new are always the most frustrating. That’s why it’s difficult to learn how to speak a new language, play an instrument, hit a golf ball, or shoot great photos. It’s so much easier to watch TV or surf the web . . . In The First 20 Hours, Josh Kaufman offers a systematic approach to rapid skill acquisition— how to learn any new skill as quickly as possible. His method shows you how to deconstruct com­plex skills, maximize productive practice, and remove common learning barriers. By complet­ing just 20 hours of focused, deliberate practice you’ll go from knowing absolutely nothing to performing noticeably well. Kaufman personally field-tested the meth­ods in this book. You’ll have a front row seat as he develops a personal yoga practice, writes his own web-based computer programs, teaches himself to touch type on a nonstandard key­board, explores the oldest and most complex board game in history, picks up the ukulele, and learns how to windsurf. Here are a few of the sim­ple techniques he teaches: Define your target performance level: Fig­ure out what your desired level of skill looks like, what you’re trying to achieve, and what you’ll be able to do when you’re done. The more specific, the better. Deconstruct the skill: Most of the things we think of as skills are actually bundles of smaller subskills. If you break down the subcompo­nents, it’s easier to figure out which ones are most important and practice those first. Eliminate barriers to practice: Removing common distractions and unnecessary effort makes it much easier to sit down and focus on deliberate practice. Create fast feedback loops: Getting accu­rate, real-time information about how well you’re performing during practice makes it much easier to improve. Whether you want to paint a portrait, launch a start-up, fly an airplane, or juggle flaming chain­saws, The First 20 Hours will help you pick up the basics of any skill in record time . . . and have more fun along the way.




Introduction to Electric Power and Drive Systems


Book Description

An introduction to the analysis of electric machines, power electronic circuits, electric drive performance, and power systems This book provides students with the basic physical concepts and analysis tools needed for subsequent coursework in electric power and drive systems with a focus on Tesla’s rotating magnetic field. Organized in a flexible format, it allows instructors to select material as needed to fit their school’s power program. The first chapter covers the fundamental concepts and analytical methods that are common to power and electric drive systems. The subsequent chapters offer introductory analyses specific to electric machines, power electronic circuits, drive system performance and simulation, and power systems. In addition, this book: Provides students with an analytical base on which to build in advanced follow-on courses Examines fundamental power conversions (dc-dc, ac-dc and dc-ac), harmonics, and distortion Describes the dynamic computer simulation of a brushless dc drive to illustrate its performance with both a sinusoidal inverter voltage approximation and more realistic stator six-step drive applied voltages Includes in-chapter short problems, numerous worked examples, and end-of-chapter problems to help readers review and more fully understand each topic




The Power to Harm


Book Description

On September 14, 1989, Joseph Wesbecker entered a Louisville, Kentucky printing plant and shot twenty people with an automatic rifle before turning the gun on himself. Wesbecker had been severely depressed and was taking Prozac, and the families of the victims sued Prozac's manufacturer, Eli Lilly, on the grounds that the popular antidepressant had caused Wesbecker's deranged mental state. The resulting trial instigated unprecedented research into the mind of a "spree killer" — and raised provocative questions about the delicate, dangerous balance pharmaceutical companies must oversee between the public good and the bottom line. In this absorbing book, John Cornwell interweaves the Wesbecker trial with a provocative exploration of issues of identity and personality. He takes us beyond the courtroom and into the laboratories and boardrooms of the corporations who daily make life-and-death decisions concerning the public welfare. The result is a timely, compelling look at what it means and what can happen when science gives us the ability to manipulate who we are and how we behave.




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