Concepts and Experimental Protocols of Modelling and Informatics in Drug Design


Book Description

Concepts and Experimental Protocols of Modelling and Informatics in Drug Design discusses each experimental protocol utilized in the field of bioinformatics, focusing especially on computer modeling for drug development. It helps the user in understanding the field of computer-aided molecular modeling (CAMM) by presenting solved exercises and examples. The book discusses topics such as fundamentals of molecular modeling, QSAR model generation, protein databases and how to use them to select and analyze protein structure, and pharmacophore modeling for drug targets. Additionally, it discusses data retrieval system, molecular surfaces, and freeware and online servers. The book is a valuable source for graduate students and researchers on bioinformatics, molecular modeling, biotechnology and several members of biomedical field who need to understand more about computer-aided molecular modeling. - Presents exercises with solutions to aid readers in validating their own protocol - Brings a thorough interpretation of results of each exercise to help readers compare them to their own study - Explains each parameter utilized in the algorithms to help readers understand and manipulate various features of molecules and target protein to design their study




Protocols, Servers and Projects for Multimedia Realtime Systems


Book Description

This book addresses the changing role of networks and the evolving structure of an Infrastructure Superhighway. The requirements for leadership in telecommunications are reviewed from different viewpoints: Network operators, equipment manufacturers, software developers and user organizations. Emphasis is placed on multimedia and what multimedia solutions would mean to telephone utilities and endusers. Based on extensive research undertaken in Europe, US and Japan, Dimitris Chorafas identifies new domains of applications, presents the breakthroughs which have currently been achieved and outlines the systems solutions necessary to fruitfully exploit new technology.




Medaka


Book Description

Explains the advantages of using medaka in experimental designs, to facilitate research, and to stimulate progress by adopting medaka as a model animal The second volume of Medaka: Biology, Management, and Experimental Protocols, together with the first volume, helps to familiarize scientists with the advantages of using medaka in experimental designs, to facilitate research using medaka, and to stimulate progress by adopting medaka as a model animal. The second edition expands on the first by providing additional information and current protocols that have been recently developed, or modified, to successfully raise medaka fish under stable culture conditions in the laboratory. This volume explores new technologies developed after 2009, using the fish as a molecular tool in the fields of life science, evolution, ecology, and toxicology. The authors—noted experts in the field—provide the latest information that spans the varied research disciplines and addresses the value to science of medaka's adoption as a model animal. This important book: Explores the advantages of using medaka in experimental designs, to facilitate research Details the most recent protocols to successfully raise medaka fish under stable conditions in the laboratory Explores the most recent developments in the field Provides step-by step specifics for each protocol, allowing researchers to adapt them for use in their own work Written for students and researchers in fish biology and aquaculture, Medaka: Biology, Management, and Experimental Protocols, Volume 2 introduces the cutting edge research in basic and applied biology using medaka as a model animal as well as descriptions of experimental methods and protocols.




Program Solicitation


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 The Transfer Protocol


Book Description

A SCI-FI THRILLER THAT DELVES INTO THE MYSTERIES OF MAN’S GREATEST GIFT—THE MIND Do you wish to explore the mind’s unimaginable power as it seeks justice in a world tarnished by corrupt beings? Join brain cell biologist Dr Almast Newhart in his mind-boggling mission to rescue his loved ones from the evil clutches of Colonel Toros and his men. Guided by a team of well-wishers, his own mental prowess and the mysterious ‘golden beings’, Almast tries to pull off the impossible. Will he emerge successful or will he lose all that he has in the process? And what is ‘the transfer protocol’? Is it just another experiment or something else?? Read on to find out.




FCC Record


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Experimental Design for Biologists


Book Description

The effective design of scientific experiments is critical to success, yet graduate students receive very little formal training in how to do it. Based on a well-received course taught by the author, Experimental Design for Biologistsfills this gap. Experimental Design for Biologistsexplains how to establish the framework for an experimental project, how to set up a system, design experiments within that system, and how to determine and use the correct set of controls. Separate chapters are devoted to negative controls, positive controls, and other categories of controls that are perhaps less recognized, such as “assumption controls†and “experimentalist controls†. Furthermore, there are sections on establishing the experimental system, which include performing critical “system controls†. Should all experimental plans be hypothesis-driven? Is a question/answer approach more appropriate? What was the hypothesis behind the Human Genome Project? What color is the sky? How does one get to Carnegie Hall? The answers to these kinds of questions can be found in Experimental Design for Biologists. Written in an engaging manner, the book provides compelling lessons in framing an experimental question, establishing a validated system to answer the question, and deriving verifiable models from experimental data. Experimental Design for Biologistsis an essential source of theory and practical guidance in designing a research plan.