› › Protein Engineering For Therapeutics

Protein Engineering

Author : Huimin Zhao

Publisher : John Wiley & Sons

Page : 41 pages

File Size : 13,75 MB

Release : 2021-08-23

Category : Science

ISBN : 3527344705

Get eBook

Book Description

A one-stop reference that reviews protein design strategies to applications in industrial and medical biotechnology Protein Engineering: Tools and Applications is a comprehensive resource that offers a systematic and comprehensive review of the most recent advances in the field, and contains detailed information on the methodologies and strategies behind these approaches. The authors—noted experts on the topic—explore the distinctive advantages and disadvantages of the presented methodologies and strategies in a targeted and focused manner that allows for the adaptation and implementation of the strategies for new applications. The book contains information on the directed evolution, rational design, and semi-rational design of proteins and offers a review of the most recent applications in industrial and medical biotechnology. This important book: Covers technologies and methodologies used in protein engineering Includes the strategies behind the approaches, designed to help with the adaptation and implementation of these strategies for new applications Offers a comprehensive and thorough treatment of protein engineering from primary strategies to applications in industrial and medical biotechnology Presents cutting edge advances in the continuously evolving field of protein engineering Written for students and professionals of bioengineering, biotechnology, biochemistry, Protein Engineering: Tools and Applications offers an essential resource to the design strategies in protein engineering and reviews recent applications.



Protein Therapeutics, 2 Volume Set

Author : Tristan Vaughan

Publisher : John Wiley & Sons

Page : 762 pages

File Size : 48,46 MB

Release : 2017-12-04

Category : Medical

ISBN : 3527340866

Get eBook

Book Description

Branchenführende Big-Pharma-Unternehmen und erstklassige Forscher präsentieren grundlegende Konzepte und Herausforderungen bei proteinbasierten Pharmazeutika. Beinhaltet auch eine Einführung in die aus Sicht der Arzneimittelentwicklung fünf wesentlichen Anwendungsbereiche.



Medicinal Protein Engineering

Author : Yury E. Khudyakov

Publisher : CRC Press

Page : 588 pages

File Size : 34,69 MB

Release : 2008-12-01

Category : Medical

ISBN : 1420007300

Get eBook

Book Description

An All-Inclusive Review of the Achievements and Trends in the Fast-Growing Protein Engineering Field From humble beginnings like making fire for mere survival, engineering now steadfastly penetrates all aspects of our lives and even life itself at the molecular level. Protein engineering is a molecular biological discipline focused on designing and



Therapeutic Antibody Engineering

Author : William R Strohl

Publisher : Elsevier

Page : 697 pages

File Size : 12,58 MB

Release : 2012-10-16

Category : Medical

ISBN : 1908818093

Get eBook

Book Description

The field of antibody engineering has become a vital and integral part of making new, improved next generation therapeutic monoclonal antibodies, of which there are currently more than 300 in clinical trials across several therapeutic areas. Therapeutic antibody engineering examines all aspects of engineering monoclonal antibodies and analyses the effect that various genetic engineering approaches will have on future candidates. Chapters in the first part of the book provide an introduction to monoclonal antibodies, their discovery and development and the fundamental technologies used in their production. Following chapters cover a number of specific issues relating to different aspects of antibody engineering, including variable chain engineering, targets and mechanisms of action, classes of antibody and the use of antibody fragments, among many other topics. The last part of the book examines development issues, the interaction of human IgGs with non-human systems, and cell line development, before a conclusion looking at future issues affecting the field of therapeutic antibody engineering. - Goes beyond the standard engineering issues covered by most books and delves into structure-function relationships - Integration of knowledge across all areas of antibody engineering, development, and marketing - Discusses how current and future genetic engineering of cell lines will pave the way for much higher productivity



Therapeutic Proteins

Author : Vladimir Voynov

Publisher : Humana Press

Page : 516 pages

File Size : 34,13 MB

Release : 2016-05-01

Category : Medical

ISBN : 9781493959495

Get eBook

Book Description

Emphasizing the newest developments in the field, this volume presents detailed methodswith added emphasison therapeutic protein discovery. It features key tips and valuable implementation advice to ensure successful results."



Protein Engineering and Design

Author : Sheldon J. Park

Publisher : CRC Press

Page : 434 pages

File Size : 49,62 MB

Release : 2009-09-25

Category : Medical

ISBN : 1420076590

Get eBook

Book Description

Experimental protein engineering and computational protein design are broad but complementary strategies for developing proteins with altered or novel structural properties and biological functions. By describing cutting-edge advances in both of these fields, Protein Engineering and Design aims to cultivate a synergistic approach to protein science



Antibody Engineering

Author : J. Donald Capra

Publisher : Karger Publishers

Page : 218 pages

File Size : 26,47 MB

Release : 1997

Category : Medical

ISBN : 9783805563567

Get eBook

Book Description

The last decade has witnessed remarkable developments in antibody research and its therapeutic applications. With the methods of molecular biology it is now possible to manipulate the specificities and activities of antibody molecules to generate an almost limitless array of structures for both basic investigations and the clinical setting. The contributions to this volume cover all three domains of the antibody: the variable regions, the relatively neglected but crucial hinge, and the constant region. These studies provide critical structural and functional information about antibodies, while also pointing the way to the construction of molecules with enhanced or even novel properties. Bringing together major experts on antibody engineering, this book is highly recommended to faculty, postdoctoral fellows and graduate students in molecular biology, microbiology, immunology, cancer research and genetics.



Protein Engineering Techniques

Author : Krishna Mohan Poluri

Publisher : Springer

Page : 144 pages

File Size : 21,41 MB

Release : 2016-11-12

Category : Technology & Engineering

ISBN : 9811027323

Get eBook

Book Description

This brief provides a broad overview of protein-engineering research, offering a glimpse of the most common experimental methods. It also presents various computational programs with applications that are widely used in directed evolution, computational and de novo protein design. Further, it sheds light on the advantages and pitfalls of existing methodologies and future perspectives of protein engineering techniques.



Introduction to Antibody Engineering

Author : Florian Rüker

Publisher : Springer Nature

Page : 388 pages

File Size : 31,93 MB

Release : 2021-01-04

Category : Medical

ISBN : 3030546306

Get eBook

Book Description

This highly readable textbook serves as a concise and engaging primer to the emerging field of antibody engineering and its various applications. It introduces readers to the basic science and molecular structure of antibodies, and explores how to characterize and engineer them. Readers will find an overview of the latest methods in antibody identification, improvement and biochemical engineering. Furthermore, alternative antibody formats and bispecific antibodies are discussed. The book’s content is based on lectures for the specializations “Protein Engineering” and “Medical Biotechnology” within the Master’s curriculum in “Biotechnology.” The lectures have been held at the University of Natural Resources and Life Sciences, Vienna, in cooperation with the Medical University of Vienna, since 2012 and are continuously adapted to reflect the latest developments in the field. The book addresses Master’s and PhD students in biotechnology, molecular biology and immunology, and all those who are interested in antibody engineering.



Protein Engineering for Therapeutics

Author : K. Dane Wittrup

Publisher : Academic Press

Page : 399 pages

File Size : 19,90 MB

Release : 2012

Category : Electronic books

ISBN : 012396962X

Get eBook

Book Description

This volume of Methods in Enzymology looks at Protein Engineering for Therapeutics. The chapters provide an invaluable resource for academics, researchers and students alike. With an international board of authors, this volume is split into sections that cover subjects such as Peptides, and Scaffolds Chapters provide an invaluable resource for academics, researchers and students alike. Iinternational board of authors. This volume is split into sections that cover subjects such as Peptides, and Scaffolds