Pediatric Critical Care Study Guide


Book Description

This is the first comprehensive study guide covering all aspects of pediatric critical care medicine. It fills a void that exists in learning resources currently available to pediatric critical care practitioners. The major textbooks are excellent references, but do not allow concise reading on specific topics and are not intended to act as both text and study guide. There are also several handbooks available, but these are usually written for general pediatric residents and lack the advanced physiology and pathophysiology required for the higher level pediatric critical care practitioner




Lung, Pleura, and Mediastinum


Book Description




Anatomy and Physiology


Book Description




The Respiratory System


Book Description

This is an integrated textbook on the respiratory system, covering the anatomy, physiology and biochemistry of the system, all presented in a clinically relevant context appropriate for the first two years of the medical student course. - One of the seven volumes in the Systems of the Body series. - Concise text covers the core anatomy, physiology and biochemistry in an integrated manner as required by system- and problem-based medical courses. - The basic science is presented in the clinical context in a way appropriate for the early part of the medical course. - There is a linked website providing self-assessment material ideal for examination preparation.




How Tobacco Smoke Causes Disease


Book Description

This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.




Lung Development


Book Description

Knowledge about the mechanisms of lung development has been growing rapidly, especially with regard to cellular and molecular aspects of growth and differentiation. This authoritative international volume reviews key aspects of lung development in health and disease by providing a comprehensive review of the complex series of cellular and molecular interactions required for lung development. It covers such topics as pulmonary hypoplasia, effects of malnutrition, and pulmaonary angiogenesis. An indispensable reference for all those involved in studying or treating lung disease in neonates and children, the book offers a unique view of the development of this essential organ.




Anatomy & Physiology


Book Description

A version of the OpenStax text




Pulmonary Function Testing


Book Description

This book serves as a unique, comprehensive resource for physicians and scientists training in pulmonary medicine and learning about pulmonary function testing. Pulmonary function testing and the physiological principles that underlie it are often poorly understood by medical students, residents, fellows and graduate students training in the medical sciences. One reason is that students tend to get overwhelmed by the basic mathematical descriptions that explain the working of the respiratory system and the principles of pulmonary function testing. Another reason is that too many approaches focus on the math without explaining the clinical relevance of these principles and the laboratory testing that enables us to measure the very lung function that these principles are describing. This book answers that need by providing a series of chapters that guide the reader in a natural order of learning about the respiratory system. In particular, after a general overview of the structure-function design of the lung and the history of pulmonary function testing, authors begin with the drive to breathe, and then follow the pathway of air as it is drawn into the lung, undergoes gas exchange, and is then exhaled back out again. Each chapter focuses on the key principles and corresponding pulmonary function tests that explain each step in this pathway. Each chapter is written by at least two experts, one with expertise in the underlying physiology, and the other with expertise in the clinical testing and application of pulmonary function testing in practice. Many figures and tables highlight key points, and multiple case studies in each section provide specific examples of the clinical application of each pulmonary function test. This is an ideal guide to pulmonary function tests for practicing pulmonologists, residents, fellows, and medical students.




Morphometry of the Human Lung


Book Description

Morphometry of the Human Lung considers the developments in understanding the quantitative anatomy of the lung, and in the correlation of anatomy with physiology. This book is composed of 11 chapters, and begins with an overview of a systematic approach to a quantitative morphologic analysis of the architecture of the human lung, followed by a presentation of general problems of methodology and the derivation of reliable dimensional models of this organ. The subsequent chapters describe the methods of preparation of tissues, methods of random sampling, and adaptation of methodologies from other fields of science. These topics are followed by discussions the mathematical formulations for the translation of the data into the desired geometric forms and a technique of counting. The final chapters look into the mode of distribution and geometric forms that should eventually facilitate mathematical and physical considerations regarding the function of the lungs. These chapters also consider the application of these quantitative methods to the study of pathologic specimens, providing a most timely renovation of morphologic pathology. This book will be of value to pulmonologists, physiologists, and researchers who are interested in lung morphometry.




Fetal and Neonatal Lung Development


Book Description

Lung disease affects more than 600 million people worldwide. While some of these lung diseases have an obvious developmental component, there is growing appreciation that processes and pathways critical for normal lung development are also important for postnatal tissue homeostasis and are dysregulated in lung disease. This book provides an authoritative review of fetal and neonatal lung development and is designed to provide a diverse group of scientists, spanning the basic to clinical research spectrum, with the latest developments on the cellular and molecular mechanisms of normal lung development and injury-repair processes, and how they are dysregulated in disease. The book covers genetics, omics, and systems biology as well as new imaging techniques that are transforming studies of lung development. The reader will learn where the field of lung development has been, where it is presently, and where it is going in order to improve outcomes for patients with common and rare lung diseases.