Molecular Biology of the Cell
Author :
Publisher :
Page : 0 pages
File Size : 14,53 MB
Release : 2002
Category : Cells
ISBN : 9780815332183
Channels, Carriers, and Pumps
Author : Wilfred D. Stein
Publisher : Elsevier
Page : 423 pages
File Size : 43,13 MB
Release : 2014-12-09
Category : Science
ISBN : 0124165834
Book Description
An introduction to the principles of membrane transport: How molecules and ions move across the cell membrane by simple diffusion and by making use of specialized membrane components (channels, carriers, and pumps). The text emphasizes the quantitative aspects of such movement and its interpretation in terms of transport kinetics. Molecular studies of channels, carriers, and pumps are described in detail as well as structural principles and the fundamental similarities between the various transporters and their evolutionary interrelationships. The regulation of transporters and their role in health and disease are also considered. - Provides an introduction to the properties of transport proteins: channels, carriers, and pumps - Presents up-to-date information on the structure of transport proteins and on their function and regulation - Includes introductions to transport kinetics and to the cloning of genes that code transport proteins - Furnishes a link between the experimental basis of the subject and theoretical model building
Optogenetics
Author : Hiromu Yawo
Publisher : Springer Nature
Page : 648 pages
File Size : 49,29 MB
Release : 2021-01-05
Category : Medical
ISBN : 9811587639
Book Description
This book, now in a thoroughly revised second edition, offers a comprehensive review of the rapidly growing field of optogenetics, in which light-sensing proteins are genetically engineered into cells in order to acquire information on cellular physiology in optical form or to enable control of specific network in the brain upon activation by light. Light-sensing proteins of various living organisms are now available to be exogenously expressed in neurons and other target cells both in vivo and in vitro. Cellular functions can thus be manipulated or probed by light. The new edition documents fully the extensive progress since publication of the first edition to provide an up-to-date overview of the physical, chemical, and biological properties of light-sensing proteins and their application in biological systems, particularly in neuroscience but also in medicine and the optical sciences. Underlying principles are explained and detailed information provided on a wide range of optogenetic tools for the observation and control of cellular signaling and physiology, gene targeting technologies, and optical methods for biological applications. In presenting the current status of optogenetics and emerging directions, this milestone publication will be a “must read” for all involved in research in any way related to optogenetics.
Computational Cell Biology
Author : Christopher P. Fall
Publisher : Springer Science & Business Media
Page : 484 pages
File Size : 19,71 MB
Release : 2007-06-04
Category : Science
ISBN : 0387224599
Book Description
This textbook provides an introduction to dynamic modeling in molecular cell biology, taking a computational and intuitive approach. Detailed illustrations, examples, and exercises are included throughout the text. Appendices containing mathematical and computational techniques are provided as a reference tool.
Pumps, Transporters, and Ion Channels
Author : Francisco Sepulveda
Publisher : Springer Science & Business Media
Page : 175 pages
File Size : 12,82 MB
Release : 2006-03-30
Category : Science
ISBN : 0387274243
Book Description
This book is a compilation of articles based on some of the talks given at the Centro de Estudios Cientificos (CECS) in Valdivia during the course of a celebration to th mark the 60 birthdays of Ramon Latorre and Enrico Stefani. Ramon Latorre is one of the most outstanding figures in channel Biophysics today. The first surprise is that he trained as a Biochemist! He soon, however, became a biophysicist through his work with Guayo (Eduardo) Rojas who guided him during his Ph. D thesis in the Laboratorio de Fisiologia Celular in Montemar. His work at N.I.H with Gerald Eherenstein and Harold Lecar constitutes one of the milestones of single ion channel Biophysics. This classical work, done in planar bilayers, set the basis for understanding voltage-dependent conductances with single channel studies and predates, by many years, later studies using patch clamping techniques. Ramon was one of the firsts to find and recognize the importance of calci- activated potassium channels and to begin a detailed study of channel properties. He pioneered the ideas of voltage and calcium modulation of the open probability and he added detailed studies of gating and its modulation by other ions. Ramon is also interested in permeation and selectivity and he produced classical studies on the number of water molecules in the channel and sites occupied by barium. Results and concepts that have recently taken front page as the structure of KcSa has been described.
Plant Nutrition
Author : Walter Horst
Publisher : Springer Science & Business Media
Page : 1068 pages
File Size : 34,60 MB
Release : 2006-05-18
Category : Science
ISBN : 030647624X
Book Description
This volume is a compilation of extended abstracts of all papers presented at the 14th International Plant Nutrition Colloquium. Over 500 oral and poster presentations illustrate current knowledge and research emphasis in this subject, providing a comprehensive view of the state of plant nutrition research.
Ionic Channels of Excitable Membranes
Author : Bertil Hille
Publisher : Sinauer Associates, Incorporated
Page : 638 pages
File Size : 34,65 MB
Release : 1992
Category : Medical
ISBN :
Book Description
This new, fully revised and expanded edition of Ionic Channels of Excitable Membranes includes new chapters on fast chemical synapses, modulation through G protein coupled receptors and second messenger systems, molecules cloning, site directed mutagenesis, and cell biology. It begins with the classical biophysical work of Hodgkin and Huxley and then weaves a description of the known ionic channels together with their biological functions. The book continues by developing the physical and molecular principles needed for explaining permeation, gating, pharmacological modification, and molecular diversity, and ends with a discussion of channel evolution. Ionic Channels of Excitable Membranes is written to be accessible and interesting to biological and physical scientists of all kinds.
Cell Biology by the Numbers
Author : Ron Milo
Publisher : Garland Science
Page : 400 pages
File Size : 36,90 MB
Release : 2015-12-07
Category : Science
ISBN : 1317230698
Book Description
A Top 25 CHOICE 2016 Title, and recipient of the CHOICE Outstanding Academic Title (OAT) Award. How much energy is released in ATP hydrolysis? How many mRNAs are in a cell? How genetically similar are two random people? What is faster, transcription or translation?Cell Biology by the Numbers explores these questions and dozens of others provid
Ion Channel Diseases
Author :
Publisher : Academic Press
Page : 168 pages
File Size : 47,61 MB
Release : 2011-09-06
Category : Science
ISBN : 0080923100
Book Description
Ion channel dysfunction in humans leads to impairment of the excitable processes necessary for the normal function of several tissues, such as muscle and brain. It follows that an increasing number of human diseases have been associated with malfunctioning ion channels, many of which have a genetic component. This volume of Advances in Genetics presents a broad and comprehensive overview of the inherited channelopathies in humans, including clinical, genetic and molecular aspects of these conditions. Keeping true to the scope of the serial, novel genomic and modeling research approaches and a review of potential therapeutic approaches for each of these conditions are also incorporated.
Bioenergetics
Author : David G. Nicholls
Publisher : Academic Press
Page : 434 pages
File Size : 48,78 MB
Release : 2013-05-20
Category : Science
ISBN : 0123884314
Book Description
Extensively revised, the fourth edition of this highly successful book takes into account the many newly determined protein structures that provide molecular insight into chemiosmotic energy transduction, as well as reviewing the explosive advances in 'mitochondrial physiology'-the role of the mitochondria in the life and death of the cell. Covering mitochondria, bacteria and chloroplasts, the fourth edition of Bioenergetics provides a clear and comprehensive account of the chemiosmotic theory and its many applications. The figures have been carefully designed to be memorable and to convey the key functional and mechanistic information. Written for students and researchers alike, Bioenergetics is the most well-known, current and respected text on chemiosmotic theory and membrane bioenergetics available. - BMA Medical Book Awards 2014-Highly Commended, Basic and Clinical Sciences,2014,British Medical Association - Chapters are now divided between three interlocking sections: basic principles, structures and mechanisms, and mitochondrial physiology - Covers new advances in the structure and mechanism of key bioenergetic proteins, including complex I of the respiratory chain and transport proteins - Details cellular bioenergetics, mitochondrial cell biology and signal transduction, and the roles of mitochondria in physiology, disease and aging - Offers readers clear, visual representation of structural concepts through full colour figures throughout the book
