Residue-residue Contact Predictions Using Neural Networks and Selected Statistics
Author : George Shackelford
Publisher :
Page : 312 pages
File Size : 30,64 MB
Release : 2010
Category :
ISBN :
Author : George Shackelford
Publisher :
Page : 312 pages
File Size : 30,64 MB
Release : 2010
Category :
ISBN :
Author : Yaoqi Zhou
Publisher : Humana
Page : 0 pages
File Size : 12,15 MB
Release : 2016-10-28
Category : Science
ISBN : 9781493964048
This thorough volume explores predicting one-dimensional functional properties, functional sites in particular, from protein sequences, an area which is getting more and more attention. Beginning with secondary structure prediction based on sequence only, the book continues by exploring secondary structure prediction based on evolution information, prediction of solvent accessible surface areas and backbone torsion angles, model building, global structural properties, functional properties, as well as visualizing interior and protruding regions in proteins. Written for the highly successful Methods in Molecular Biology series, the chapters include the kind of detail and implementation advice to ensure success in the laboratory. Practical and authoritative, Prediction of Protein Secondary Structure serves as a vital guide to numerous state-of-the-art techniques that are useful for computational and experimental biologists.
Author : Neocles Leontis
Publisher : Springer Science & Business Media
Page : 402 pages
File Size : 43,47 MB
Release : 2012-06-05
Category : Science
ISBN : 3642257402
With the dramatic increase in RNA 3D structure determination in recent years, we now know that RNA molecules are highly structured. Moreover, knowledge of RNA 3D structures has proven crucial for understanding in atomic detail how they carry out their biological functions. Because of the huge number of potentially important RNA molecules in biology, many more than can be studied experimentally, we need theoretical approaches for predicting 3D structures on the basis of sequences alone. This volume provides a comprehensive overview of current progress in the field by leading practitioners employing a variety of methods to model RNA 3D structures by homology, by fragment assembly, and by de novo energy and knowledge-based approaches.
Author : Mario Giacobini
Publisher : Springer
Page : 266 pages
File Size : 43,54 MB
Release : 2012-03-23
Category : Computers
ISBN : 3642290663
This book constitutes the refereed proceedings of the 10th European Conference on Evolutionary Computation, Machine Learning and Data Mining in Bioinformatics, EvoBIO 2012, held in Málaga, Spain, in April 2012 co-located with the Evo* 2012 events. The 15 revised full papers presented together with 8 poster papers were carefully reviewed and selected from numerous submissions. Computational Biology is a wide and varied discipline, incorporating aspects of statistical analysis, data structure and algorithm design, machine learning, and mathematical modeling toward the processing and improved understanding of biological data. Experimentalists now routinely generate new information on such a massive scale that the techniques of computer science are needed to establish any meaningful result. As a consequence, biologists now face the challenges of algorithmic complexity and tractability, and combinatorial explosion when conducting even basic analyses.
Author : Clara Pizzuti
Publisher : Springer Science & Business Media
Page : 193 pages
File Size : 20,97 MB
Release : 2011-04-19
Category : Computers
ISBN : 3642203884
This book constitutes the refereed proceedings of the 9th European Conference on Evolutionary Computation, Machine Learning and Data Mining in Bioinformatics, EvoBIO 2011, held in Torino, Italy, in April 2011 co-located with the Evo* 2011 events. The 12 revised full papers presented together with 7 poster papers were carefully reviewed and selected from numerous submissions. All papers included topics of interest such as biomarker discovery, cell simulation and modeling, ecological modeling, fluxomics, gene networks, biotechnology, metabolomics, microarray analysis, phylogenetics, protein interactions, proteomics, sequence analysis and alignment, and systems biology.
Author : Monica Bianchini
Publisher : Springer Science & Business Media
Page : 547 pages
File Size : 17,95 MB
Release : 2013-04-12
Category : Technology & Engineering
ISBN : 3642366570
This handbook presents some of the most recent topics in neural information processing, covering both theoretical concepts and practical applications. The contributions include: Deep architectures Recurrent, recursive, and graph neural networks Cellular neural networks Bayesian networks Approximation capabilities of neural networks Semi-supervised learning Statistical relational learning Kernel methods for structured data Multiple classifier systems Self organisation and modal learning Applications to content-based image retrieval, text mining in large document collections, and bioinformatics This book is thought particularly for graduate students, researchers and practitioners, willing to deepen their knowledge on more advanced connectionist models and related learning paradigms.
Author : David B. Weiner
Publisher : CRC Press
Page : 298 pages
File Size : 23,76 MB
Release : 2020-12-18
Category : Medical
ISBN : 1000142183
This book is the first to provide both a broad overview of the current methodologies being applied to drug design and in-depth analyses of progress in specific fields. It details state-of-the-art approaches to pharmaceutical development currently used by some of the world's foremost laboratories. The book features contributors from a variety of fields, new techniques, previously unpublished data, and extensive reference lists.
Author : Alvis Brazma
Publisher : World Scientific
Page : 413 pages
File Size : 17,39 MB
Release : 2008
Category : Science
ISBN : 1848161085
High-throughput sequencing and functional genomics technologies have given us the human genome sequence as well as those of other experimentally, medically, and agriculturally important species, thus enabling large-scale genotyping and gene expression profiling of human populations. Databases containing large numbers of sequences, polymorphisms, structures, metabolic pathways, and gene expression profiles of normal and diseased tissues are rapidly being generated for human and model organisms. Bioinformatics is therefore gaining importance in the annotation of genomic sequences; the understanding of the interplay among and between genes and proteins; the analysis of the genetic variability of species; the identification of pharmacological targets; and the inference of evolutionary origins, mechanisms, and relationships. This proceedings volume contains an up-to-date exchange of knowledge, ideas, and solutions to conceptual and practical issues of bioinformatics by researchers, professionals, and industry practitioners at the 6th Asia-Pacific Bioinformatics Conference held in Kyoto, Japan, in January 2008.
Author : Ewa Piętka
Publisher : Springer
Page : 400 pages
File Size : 43,44 MB
Release : 2016-05-27
Category : Technology & Engineering
ISBN : 3319399047
ITiB’2016 is the 5th Conference on Information Technologies in Biomedicine organized by the Department of Informatics & Medical Equipment of Silesian University of Technology every other year. The Conference is under the auspices of the Committee on Biocybernetics and Biomedical Engineering of the Polish Academy of Sciences. The meeting has become a recognized event that helps to bridge the gap between methodological achievements in engineering and clinical requirements in medical diagnosis, therapy, and rehabilitation. Mathematical information analysis, computer applications together with medical equipment and instruments have become standard tools underpinning the current rapid progress with developing Computational Intelligence. Members of academic societies of technical and medical background present their research results and clinical implementations. This proceedings (divided in 2 volumes) include the following sections: ؠ Image Processing ؠ Signal Processing ؠ Medical Information System & Database ؠ Ambient Assisted Living ؠ Bioinformatics ؠ Modeling & Simulation ؠ Biomechatronics ؠ Biomaterials
Author : Khalid Raza
Publisher : Elsevier
Page : 299 pages
File Size : 49,1 MB
Release : 2024-03-07
Category : Technology & Engineering
ISBN : 0443222983
Deep Learning Applications in Translational Bioinformatics, a new volume in the Advances in Ubiquitous Sensing Application for Healthcare series, offers a detailed overview of basic bioinformatics, deep learning, various applications of deep learning in translational bioinformatics including deep learning ensembles, deep learning in protein classification, detection of various diseases, prediction of antiviral peptides, identification of antibiotic resistance, computer aided drug design and drug formulation. This new volume helps researchers working in the field of machine learning and bioinformatics to foster future research and development in ensemble deep learning and inspire new bioinformatics applications that cannot be attained by using traditional machine learning models. - Addresses the practical application of deep learning algorithms to a wide range of bioinformatics challenges - Presents integrative and multidisciplinary approaches to ubiquitous healthcare - Includes case studies to illustrate the concepts discussed