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RNA-Protein Complexes and Interactions

Author : Ren-Jang Lin

Publisher : Humana

Page : 0 pages

File Size : 42,96 MB

Release : 2023-06-12

Category : Science

ISBN : 9781071631935

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Book Description

This second edition updates, complements, and expands upon the first edition by providing a collection of cutting-edge techniques developed or refined in the past few years along with tried-and-true methods. Chapters explore the isolation and characterization of RNA-protein complexes, the analysis and measurement of RNA-protein interaction, and related novel techniques and strategies. Written in the highly successful Methods in Molecular Biology series format, the chapters include brief introductions to the material, lists of necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and a Notes section which highlights tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, RNA-Protein Complexes and Interactions: Methods and Protocols, Second Edition aims to be comprehensive guide for researchers in the field.



Biophysics of RNA-Protein Interactions

Author : Chirlmin Joo

Publisher : Springer Nature

Page : 249 pages

File Size : 33,47 MB

Release : 2019-09-19

Category : Science

ISBN : 1493997262

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Book Description

RNA molecules play key roles in all aspects of cellular life, but to do so efficiently, they must work in synergism with proteins. This book addresses how proteins and RNA interact to carry out biological functions such as protein synthesis, regulation of gene expression, genome defense, liquid phase separation and more. The topics addressed in this volume will appeal to researchers in biophysics, biochemistry and structural biology. The book is a useful resource for anybody interested in elucidating the molecular mechanisms and discrete properties of RNA-protein complexes. Included are reviews of key systems such as microRNA and CRISPR/Cas that exemplify how RNA and proteins work together to perform their biological function. Also covered are techniques ranging from single molecule fluorescence and force spectroscopy to crystallography, cryo-EM microscopy, and kinetic modeling.



RNA-protein Interactions

Author : Kiyoshi Nagai

Publisher : Oxford University Press, USA

Page : 302 pages

File Size : 17,33 MB

Release : 1994

Category : Medical

ISBN :

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Book Description

The study of RNA-protein interactions is crucial to understanding the mechanisms and control of gene expression and protein synthesis. The realization that RNAs are often far more biologically active than was previously appreciated has stimulated a great deal of new research in this field. Uniquely, in this book, the world's leading researchers have collaborated to produce a comprehensive and current review of RNA-protein interactions for all scientists working in this area. Timely, comprehensive, and authoritative, this new Frontiers title will be invaluable for all researchers in molecular biology, biochemistry and structural biology.



Protein-Nucleic Acid Interactions

Author : Phoebe A. Rice

Publisher : Royal Society of Chemistry

Page : 417 pages

File Size : 21,85 MB

Release : 2008-05-22

Category : Science

ISBN : 0854042725

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Book Description

This book provides both in-depth background and up-to-date information in this area. The chapters are organized by general themes and principles, written by experts who illustrate topics with current findings. Topics covered include: - the role of ions and hydration in protein-nucleic acid interactions - transcription factors and combinatorial specificity - indirect readout of DNA sequence - single-stranded nucleic acid binding proteins - nucleic acid junctions and proteins, - RNA protein recognition - recognition of DNA damage. It will be a key reference for both advanced students and established scientists wishing to broaden their horizons.





RNA-RNA Interactions

Author : Frank J. Schmidt

Publisher : Humana Press

Page : 0 pages

File Size : 23,26 MB

Release : 2014-10-29

Category : Medical

ISBN : 9781493918959

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Book Description

In this volume expert researchers in the field detail many of the methods which are now commonly used to study RNA. These methods are presented as a guidebook to scientists who are experienced with RNA research and want to brush up on a new technique. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Thorough and intuitive, RNA-RNA Interactions: Methods and Protocols guides scientists investigating biological systems and studying RNA.



DNA-Protein Interactions

Author : Andrew Arthur Travers

Publisher : Springer Science & Business Media

Page : 194 pages

File Size : 26,48 MB

Release : 1993-04-30

Category : Medical

ISBN : 9780412259906

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Book Description

The binding of proteins to DNA and the manipulation of DNA by proteins are crucial aspects of the biological role of DNA in the living cell. This book provides a comprehensive and lucid discussion of the molecular interactions involved.



Handbook of RNA Biochemistry

Author : Roland K. Hartmann

Publisher : John Wiley & Sons

Page : 1370 pages

File Size : 21,89 MB

Release : 2015-06-22

Category : Science

ISBN : 3527327762

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Book Description

The second edition of a highly acclaimed handbook and ready reference. Unmatched in its breadth and quality, around 100 specialists from all over the world share their up-to-date expertise and experiences, including hundreds of protocols, complete with explanations, and hitherto unpublished troubleshooting hints. They cover all modern techniques for the handling, analysis and modification of RNAs and their complexes with proteins. Throughout, they bear the practising bench scientist in mind, providing quick and reliable access to a plethora of solutions for practical questions of RNA research, ranging from simple to highly complex. This broad scope allows the treatment of specialized methods side by side with basic biochemical techniques, making the book a real treasure trove for every researcher experimenting with RNA.



RNA Infrastructure and Networks

Author : Lesley J. Collins

Publisher : Springer Science & Business Media

Page : 297 pages

File Size : 19,47 MB

Release : 2011-09-15

Category : Medical

ISBN : 1461403324

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Book Description

RNAs form complexes with proteins and other RNAs. The RNA‐infrastructure represents the spatiotemporal interaction of these proteins and RNAs in a cell‐wide network. RNA Infrastructure and Networks brings together these ideas to illustrate the scope of RNA‐based biology, and how connecting RNA mechanisms is a powerful tool to investigate regulatory pathways. This book is but a taste of the wide range of RNA‐based mechanisms that connect in the RNA infrastructure.



Protein Interactions: Computational Methods, Analysis And Applications

Author : M Michael Gromiha

Publisher : World Scientific

Page : 424 pages

File Size : 16,54 MB

Release : 2020-03-05

Category : Science

ISBN : 9811211884

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Book Description

This book is indexed in Chemical Abstracts ServiceThe interactions of proteins with other molecules are important in many cellular activities. Investigations have been carried out to understand the recognition mechanism, identify the binding sites, analyze the the binding affinity of complexes, and study the influence of mutations on diseases. Protein interactions are also crucial in structure-based drug design.This book covers computational analysis of protein-protein, protein-nucleic acid and protein-ligand interactions and their applications. It provides up-to-date information and the latest developments from experts in the field, using illustrations to explain the key concepts and applications. This volume can serve as a single source on comparative studies of proteins interacting with proteins/DNAs/RNAs/carbohydrates and small molecules.