Responsible Conduct of Research


Book Description

Recent scandals and controversies, such as data fabrication in federally funded science, data manipulation and distortion in private industry, and human embryonic stem cell research, illustrate the importance of ethics in science. Responsible Conduct of Research, now in a completely updated second edition, provides an introduction to the social, ethical, and legal issues facing scientists today.




Goldfrank's Toxicologic Emergencies, Tenth Edition (ebook)


Book Description

The standard-setting reference in medical toxicology—trusted as the leading evidencebased resource for poison emergencies A Doody's Core Title for 2017! For decades, one name has been synonymous with the most respected, rigorous perspectives on medical toxicology and the treatment of poisoned and overdosed patients: Goldfrank's Toxicologic Emergencies. Presented in full color, Goldfrank’s delivers essential, patientcenteredcoverage of every aspect of poison management. The editors and authors are recognized as preeminent scholars in their specialties and provide unmatched coverage of all aspects of toxicologic emergencies, from pharmacology and clinical presentation to cutting-edge treatment strategies. Goldfrank's Toxicologic Emergencies, Tenth Edition begins with an examination of medical toxicology principles and techniques. It then reviews the biochemical, molecular, and pathophysiologic basis of toxicology, followed by an intense focus on toxicologic principles related to special patient populations. Features Case studies enhance your understanding of the clinical application of the text material Practical focus on the pathophysiologic basis of medical toxicology The Antidotes in Depth sections delivers the expertise of toxicologists across the world as they present treatments for critically ill poisoned and overdosed patients and allow you to easily identify key issues relating to the use of complex and often unfamiliar therapies The principles of risk management, medicolegal decision making, patient safety, post mortem toxicology and the assessment of ethanol induced impairment described in chapters and Special Considerations emphasize the interface between medical toxicology, the law, and quality care







Vibrant and Healthy Kids


Book Description

Children are the foundation of the United States, and supporting them is a key component of building a successful future. However, millions of children face health inequities that compromise their development, well-being, and long-term outcomes, despite substantial scientific evidence about how those adversities contribute to poor health. Advancements in neurobiological and socio-behavioral science show that critical biological systems develop in the prenatal through early childhood periods, and neurobiological development is extremely responsive to environmental influences during these stages. Consequently, social, economic, cultural, and environmental factors significantly affect a child's health ecosystem and ability to thrive throughout adulthood. Vibrant and Healthy Kids: Aligning Science, Practice, and Policy to Advance Health Equity builds upon and updates research from Communities in Action: Pathways to Health Equity (2017) and From Neurons to Neighborhoods: The Science of Early Childhood Development (2000). This report provides a brief overview of stressors that affect childhood development and health, a framework for applying current brain and development science to the real world, a roadmap for implementing tailored interventions, and recommendations about improving systems to better align with our understanding of the significant impact of health equity.




The Road to Rescue


Book Description

“A deepening of the story” of Schindler’s List: A Holocaust survivor recounts how he extracted Nazi intel for Oskar Schindler in this moving memoir of courage and resistance (New York Times Book Review). Steven Spielberg’s Oscar-winning film Schindler’s List popularized the true story of a German businessman who manipulated his Nazi connections and spent his personal fortune to save 1,200 Jewish prisoners during the Holocaust. But few know those lists were made possible by a secret strategy designed by a young Polish Jew at the Płaszow concentration camp. Mietek Pemper’s compelling and moving memoir tells the true story of how Schindler’s list really came to pass. Pemper was born in 1920 into a lively and cultivated Jewish family for whom everything changed when the Germans invaded Poland. Evicted from their home, they were forced into the Krakow ghetto and, later, into the nearby camp of Płaszow where Pemper’s knowledge of the German language was put to use by the sadistic camp commandant Amon Goth. Forced to work as Goth’s personal stenographer from March 1943 to September 1944—an exceptional job for a Jewish prisoner—Pemper soon realized that he could use his position as the commandant’s private secretary to familiarize himself with the inner workings of the Nazi bureaucracy and exploit the system to his fellow detainees’ advantage. Once he gained access to classified documents, Pemper was able to pass on secret information for Schindler to compile his famous lists. After the war, Pemper was the key witness of the prosecution in the 1946 trial against Goth and several other SS officers. The Road to Rescue stands as a historically authentic testimony of one man’s unparalleled courage, wit, defiance, and bittersweet victory over the Nazi regime.




The Handbook of Research Synthesis and Meta-Analysis


Book Description

Research synthesis is the practice of systematically distilling and integrating data from many studies in order to draw more reliable conclusions about a given research issue. When the first edition of The Handbook of Research Synthesis and Meta-Analysis was published in 1994, it quickly became the definitive reference for conducting meta-analyses in both the social and behavioral sciences. In the third edition, editors Harris Cooper, Larry Hedges, and Jeff Valentine present updated versions of classic chapters and add new sections that evaluate cutting-edge developments in the field. The Handbook of Research Synthesis and Meta-Analysis draws upon groundbreaking advances that have transformed research synthesis from a narrative craft into an important scientific process in its own right. The editors and leading scholars guide the reader through every stage of the research synthesis process—problem formulation, literature search and evaluation, statistical integration, and report preparation. The Handbook incorporates state-of-the-art techniques from all quantitative synthesis traditions and distills a vast literature to explain the most effective solutions to the problems of quantitative data integration. Among the statistical issues addressed are the synthesis of non-independent data sets, fixed and random effects methods, the performance of sensitivity analyses and model assessments, the development of machine-based abstract screening, the increased use of meta-regression and the problems of missing data. The Handbook also addresses the non-statistical aspects of research synthesis, including searching the literature and developing schemes for gathering information from study reports. Those engaged in research synthesis will find useful advice on how tables, graphs, and narration can foster communication of the results of research syntheses. The third edition of the Handbook provides comprehensive instruction in the skills necessary to conduct research syntheses and represents the premier text on research synthesis. Praise for the first edition: "The Handbook is a comprehensive treatment of literature synthesis and provides practical advice for anyone deep in the throes of, just teetering on the brink of, or attempting to decipher a meta-analysis. Given the expanding application and importance of literature synthesis, understanding both its strengths and weaknesses is essential for its practitioners and consumers. This volume is a good beginning for those who wish to gain that understanding." —Chance "Meta-analysis, as the statistical analysis of a large collection of results from individual studies is called, has now achieved a status of respectability in medicine. This respectability, when combined with the slight hint of mystique that sometimes surrounds meta-analysis, ensures that results of studies that use it are treated with the respect they deserve....The Handbook of Research Synthesis is one of the most important publications in this subject both as a definitive reference book and a practical manual."—British Medical Journal When the first edition of The Handbook of Research Synthesis was published in 1994, it quickly became the definitive reference for researchers conducting meta-analyses of existing research in both the social and biological sciences. In this fully revised second edition, editors Harris Cooper, Larry Hedges, and Jeff Valentine present updated versions of the Handbook's classic chapters, as well as entirely new sections reporting on the most recent, cutting-edge developments in the field. Research synthesis is the practice of systematically distilling and integrating data from a variety of sources in order to draw more reliable conclusions about a given question or topic. The Handbook of Research Synthesis and Meta-Analysis draws upon years of groundbreaking advances that have transformed research synthesis from a narrative craft into an important scientific process in its own right. Cooper, Hedges, and Valentine have assembled leading authorities in the field to guide the reader through every stage of the research synthesis process—problem formulation, literature search and evaluation, statistical integration, and report preparation. The Handbook of Research Synthesis and Meta-Analysis incorporates state-of-the-art techniques from all quantitative synthesis traditions. Distilling a vast technical literature and many informal sources, the Handbook provides a portfolio of the most effective solutions to the problems of quantitative data integration. Among the statistical issues addressed by the authors are the synthesis of non-independent data sets, fixed and random effects methods, the performance of sensitivity analyses and model assessments, and the problem of missing data. The Handbook of Research Synthesis and Meta-Analysis also provides a rich treatment of the non-statistical aspects of research synthesis. Topics include searching the literature, and developing schemes for gathering information from study reports. Those engaged in research synthesis will also find useful advice on how tables, graphs, and narration can be used to provide the most meaningful communication of the results of research synthesis. In addition, the editors address the potentials and limitations of research synthesis, and its future directions. The past decade has been a period of enormous growth in the field of research synthesis. The second edition Handbook thoroughly revises original chapters to assure that the volume remains the most authoritative source of information for researchers undertaking meta-analysis today. In response to the increasing use of research synthesis in the formation of public policy, the second edition includes a new chapter on both the strengths and limitations of research synthesis in policy debates




From Generation to Generation


Book Description

Immigrant children and youth are the fastest growing segment of the U.S. population, and so their prospects bear heavily on the well-being of the country. However, relevant public policy is shaped less by informed discussion than by politicized contention over welfare reform and immigration limits. From Generation to Generation explores what we know about the development of white, black, Hispanic, and Asian children and youth from numerous countries of origin. Describing the status of immigrant children and youth as "severely understudied," the committee both draws on and supplements existing research to characterize the current status and outlook of immigrant children. The book discusses the many factorsâ€"family size, fluency in English, parent employment, acculturation, delivery of health and social services, and public policiesâ€"that shape the outlook for the lives of these children and youth. The committee makes recommendations for improved research and data collection designed to advance knowledge about these children and, as a result, their visibility in current policy debates.




Argumentation in Science Education


Book Description

Educational researchers are bound to see this as a timely work. It brings together the work of leading experts in argumentation in science education. It presents research combining theoretical and empirical perspectives relevant for secondary science classrooms. Since the 1990s, argumentation studies have increased at a rapid pace, from stray papers to a wealth of research exploring ever more sophisticated issues. It is this fact that makes this volume so crucial.




Disability, Work, and Cash Benefits


Book Description

This book contains 13 papers from a workshop convened to explore the causes of work disability and the types of interventions that might enable individuals to remain at work, return to work, or enter the work force for the first time, despite having chronic health conditions or impairments. Following an overview of the papers by editors Jerry L. Mashaw and Virginia P. Reno, the following papers are included: "The Contemporary Labor Market and the Employment Prospects of Persons with Disabilities" (Edward Yelin, Miriam Cisternas); "Employment and Economic Well-Being Following the Onset of a Disability: The Role for Public Policy" (Richard V. Burkhauser, Mary C. Daly); "Employment and Benefits for People with Diverse Disabilities" (Walter Y. Oi); "European Experiences with Disability Policy" (Leo J. M. Aarts, Philip R. de Jong); "Patterns of Return to Work in a Cohort of Disabled-Worker Beneficiaries" (Martynas A. Ycas); "The Effectiveness of Financial Work Incentives in Social Security Disability Insurance and Supplemental Security Income: Lessons from Other Transfer Programs" (Hilary Williamson Hoynes, Robert Moffitt); "Lessons from the Vocational Rehabilitation/Social Security Administration Experience" (Edward Berkowitz, David Dean); "Disability and Work: Lessons from the Private Sector" (H. Allan Hunt et al.); "Quantitative Outcomes of the Transitional Employment Training Demonstration: Summary of Net Impacts" (Aaron J. Prero); "Policies for People with Disabilities in U.S. Employment and Training Programs" (Burt S. Barnow); "Improving the Return to Work of Social Security Disability Beneficiaries" (Monroe Berkowitz); "People with Disabilities: Access to Health Care and Related Benefits" (Robert B. Friedland, Alison Evans); and "Health Care, Personal Assistance and Assistive Technology: Are In-Kind Benefits Key to Independence or Dependence for People with Disabilities?" (Andrew I. Batavia). The papers contain extensive references lists. (KC)




Decisions of the Commission


Book Description