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Serum Pharmacochemistry of Traditional Chinese Medicine

Author : Xijun Wang

Publisher : Academic Press

Page : 380 pages

File Size : 21,42 MB

Release : 2016-12-27

Category : Medical

ISBN : 0128111488

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Book Description

Serum Pharmacochemistry of Traditional Chinese Medicine: Technologies, Strategies and Applications provides a valuable and indispensable guide on the latest methods, research advances, and applications in this area. Chapters offer cutting-edge information on pharmacokinetics and pharmacodynamics, analytical chemistry, traditional medicine, natural products, bioinformatics, new technologies, therapeutic applications, and more. For researchers and students in academia and industry, this book provides a hands-on description of experimental techniques, along with beneficial guidelines to help advance research in the fields of Traditional Chinese Medicine and drug development. - Provides a valuable guide for practitioners of serum pharmacochemistry of Traditional Chinese Medicine, along with insights to its current use and future applications - Edited and written by leading scientists at the forefront of this research - Presents well written chapters that include an introduction, description of the method, and identification of chemical constituents, with applications and references to the latest research and literature



Chinmedomics

Author : Xijun Wang

Publisher : Academic Press

Page : 408 pages

File Size : 27,56 MB

Release : 2015-07-15

Category : Science

ISBN : 0128031182

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Book Description

Chinmedomics: The Integration of Serum Pharmacochemistry and Metabolomics to Elucidate the Scientific Value of Traditional Chinese Medicine uses new experimental techniques and research to open doors in drug discovery and development related to traditional Chinese medicine (TCM). This book features a unique approach that combines chemometric analysis with metabolomics studies to illuminate significant changes that have occurred in syndrome states while simultaneously analyzing the efficacy of chemical ingredients in herbal medicines. Chapters provide cutting-edge information on traditional medicine, analytical technology, natural products, metabolomics, bioinformatics and their applications. This book provides a valuable resource for pharmacologists, pharmaceutical scientists, medicinal plant researchers, pharmacognosists and chemists working with TCM and highlights ways to further research and advances in this area in the future. - Presents a practical guide for new practitioners of Chinmedomics with insights on the current use and future development of this method - Each chapter includes an introduction, method, references to the latest literature, possible mechanisms of action and applications - Edited by the leading experts of research related to Chinmedomics



The Beijing Young Women’s Christian Association, 1927–1937

Author : Aihua Zhang

Publisher : Rowman & Littlefield

Page : 194 pages

File Size : 11,14 MB

Release : 2021-11-16

Category : History

ISBN : 1793608156

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Book Description

By exploring the interplay among gender, religion, and modernity, this book exposes the part Chinese Christian women played in China’s quest for a strong nation in general and in Republican Beijing’s modern transformation in particular. Focusing on the Beijing Young Women’s Christian Association (YWCA), the author examines how the Association, guided by the Christian tenet “to serve, not to be served,” tailored its Western models and devised new programs to meet the city’s demands. Its enterprises ranged from providing women- and child-oriented facilities to promoting constructive recreational activities and from reforming home and family to improving public health. Through an analysis of these endeavors, the author argues that the Chinese YW women's contribution to the city's modernity was a creative embodiment of the then socially targeted missionary movement known as the Social Gospel. In the process, they demonstrated their distinctive new ideals of womanhood featuring practicality, social service, and broad cooperation. These qualities set them apart from both traditional women and other brands of the New Woman. While criticized as trivial, their efforts, however, pioneered modern social service in China and complemented what municipal authorities and other progressive groups undertook to modernize the city.



Mass Spectrometry-Based Metabolomics in Clinical and Herbal Medicines

Author : Aihua Zhang

Publisher : John Wiley & Sons

Page : 292 pages

File Size : 49,89 MB

Release : 2021-08-20

Category : Science

ISBN : 3527835741

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Book Description

Highlights the importance and benefit of mass spectrometry-based metabolomics for identifying biomarkers that accurately screen for potential biomarkers of diseases Mass spectrometry-based metabolomics offer new opportunities for biomarker discovery in complex diseases and may provide pathological understanding of diseases beyond traditional technologies. It is the systematic analysis of low-molecular-weight metabolites in biological samples and has been applied to discovering and identifying the perturbed pathways. Currently, mass spectrometry-based metabolomics has become an important tool in clinical research and the diagnosis of human disease. Mass Spectrometry-Based Metabolomics in Clinical and Herbal Medicines comprehensively presents the current state, challenges, and applications of high-throughput mass spectrometry-based metabolomics such as metabolites analysis, biomarker discovery, technical challenges, discovery of natural product, mechanism interpretation of action, discovery of active ingredients, clinical application and precision medicine, and enhancing their biomedical value in a real world of biomedicine, shedding light on the potential for spectrometry-based metabolomics. It highlights the value of mass spectrometry-based metabolomics and metabolism to address the complexity of herbal medicines in systems pharmacology, especially, to link phytochemical analysis with the assessment of pharmacological effect and therapeutic potential. Each chapter has been laid out with introduction, method, up-to-date literature, identification of biomarker, and applications Covers the current state, challenges, and applications of high-throughput mass spectrometry-based metabolomics in the discovery of biomarker, active ingredients, natural product, etc. Constitutes a unique and indispensable practical guide for any phytochemistry or related laboratory, and provides hands-on description of new techniques Provides a guide for new practitioners of pharmacologists, pharmacological scholars, drug developers, botanist, researchers of traditional medicines. Mass Spectrometry-Based Metabolomics in Clinical and Herbal Medicines provides a landmark of mass spectrometry-based metabolomics research and a beneficial guideline to graduate students and researchers in academia, industry, and technology transfer organizations in all biomedical science fields.



Network Pharmacology

Author : Shao Li

Publisher : Springer Nature

Page : 480 pages

File Size : 28,56 MB

Release : 2021-09-29

Category : Medical

ISBN : 9811607532

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Book Description

This book introduces “network pharmacology” as an emerging frontier subject of systematic drug research in the era of artificial intelligence and big data. Network Pharmacology is an original subject of fusion system biology, bioinformatics, network science and other related disciplines. It emphasizes on starting from the overall perspective of the system level and biological networks, the analysis of the laws of molecular association between drugs and their treatment objects, reveals the systematic pharmacological mechanisms of drugs, and guides the research and development of new drugs and clinical diagnosis and treatment. After it was proposed, network pharmacology has been paid attention by researchers, and it has been rapidly developed and widely used. In order to systematically reveal the biological basis of diagnosis and treatment in traditional Chinese medicine and modern medicine, we proposed a new concept of "network target" for the first time, which has become the core theory of "network pharmacology". The core principle of a network target is to construct a biological network that can be used to decipher complex diseases. The network is then used as the therapeutic target, to which multicomponent remedies are applied. This book mainly includes four parts: 1) The concept and theory of network pharmacology; 2) Common analysis methods, databases and software in network pharmacological research; 3) Typical cases of traditional Chinese medicine modernization and modern drug research based on network pharmacology; 4) Network pharmacology practice process based on drugs and diseases.



Understanding Traditional Chinese Medicine

Author : Friedrich G. Wallner

Publisher : Peter Lang Gmbh, Internationaler Verlag Der Wissenschaften

Page : 0 pages

File Size : 10,98 MB

Release : 2009

Category : Manners and customs

ISBN : 9783631567098

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Book Description

This volume presents texts written by Austrian and Chinese experts in the field of Traditional Chinese Medicine. The issue the authors worked on is the basic problem how to make a different system of medical thinking plausible for the Western world, especially for Western medicine. This issue is considered from different viewpoints - from the viewpoint of Western medicine that is familiar with Chinese medicine and contrariwise from the viewpoint of Chinese Medicine that is familiar with its Western counterpart and from a philosophical viewpoint. In this way both differences in the theoretical systems of Western and Chinese medicine and problems of adequate translation are profundly discussed.





Dietary Chinese Herbs

Author : Yanze Liu

Publisher : Springer Science & Business Media

Page : 776 pages

File Size : 29,6 MB

Release : 2015-05-18

Category : Technology & Engineering

ISBN : 3211994483

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Book Description

This work presents up-to-date information on chemical, pharmacological, clinical studies and historical uses of common dietary Chinese herbs. Authored by native experts in the field, the reader is introduced to each herb with a brief chronological review of Chinese literature on dietary herb uses, with chapters dedicated to each selected herb including color photos for each herb. In addition, Chinese characters as well as the Latin botanical name indices, and chemical structures for the known active compounds are also provided. The clear layout examines the health benefits that have been studied for centuries, including current clinical and toxicological data. A wide range of Traditional Chinese Medicine (TCM) herbs are investigated for their suitability into daily diets for maintaining general wellness or disease prevention. In the past decades, natural health products, dietary supplements, functional foods, or nutraceuticals have emerged in the West due to the increasing demand for non-pharmaceutical healthcare products. Traditional Chinese Medicine disease prevention and treatment incorporates the use of foods, and herbal medicine in an integrated manner, and thus the dietary Chinese herbs in used in TCM for thousands of years could be sources for developing new, effective, and safe ingredients to capture the rapidly expanding opportunity in the global market place.



Systems Biology for Traditional Chinese Medicine

Author : Guoan Luo

Publisher : John Wiley & Sons

Page : 518 pages

File Size : 15,2 MB

Release : 2012-05-11

Category : Science

ISBN : 1118313356

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Book Description

The application of systems biology methods to Traditional Chinese Medicine Emphasizing the harmony of the human body with the environment, Traditional Chinese Medicine (TCM) has evolved over thousands of years. It is a systemic theory derived from clinical experience, the philosophy of holism and systematology, and the belief that man is an integral part of nature. Systems Biology for Traditional Chinese Medicine describes how the latest methods in systems biology can be applied to TCM, providing a comprehensive resource for the modernization and advancement of TCM as well as general drug discovery efforts. It is the first comprehensive work to propose a system-to-system research methodology to study the interaction between TCM and the human body and its applications in drug research and development. Using three popular traditional Chinese medicines—Shuanglongfang, Qingkailing, and Liushenwan—as examples, the authors set forth case examples demonstrating how to find material groups, perform efficacy screenings, and conduct safety evaluations of TCM. The book also: Describes the mechanisms of TCM at the molecular and systems levels using chemomics, genomics, proteomics, metabolomics, and bioinformatics Places modern scientific technologies within the context of TCM, helping drug researchers improve experimental designs and strategies Illustrates how a systems biology approach is compatible with TCM's traditional, holistic therapeutic strategies and treatment modalities Presents topics of current interest, such as integrated global systems biology and the application of chemometrics research to herbal medicines This book not only opens a new pathway for the continued development of TCM, but also for systems biology. In addition, it fosters collaboration and discussion among Eastern and Western scientists by applying systems biology to TCM.