Sex/Gender-Specific Medicine in the Gastrointestinal Diseases


Book Description

Sex/gender - specific medicine (SGM) is defined as the practice of medicine based on the understanding that biology and social roles are important in men and women for disease prevention, screening, diagnosis, and treatment. Current research demonstrates differences in disease incidence, symptomatology, morbidity, and mortality based on sex and gender. Sex/gender-specific medicine is a fundamental aspect of tailored therapy and precision medicine. Therefore, the variables must be considered in medical education and practice as well as in research models ranging from human participants, animals and cells. Gastroenterology is very big and important division of Internal Medicine, which include esophagus, stomach, small and large intestine, pancreatobiliary tract and liver. Nowadays estrogen is known to play a key role in the prevention of colon cancer and progression of liver cirrhosis and hepatocellular carcinoma, especially in women. This book covers the sex/gender-specific medicine in the area of gastrointestinal (GI) tract in the adults as well as in the pediatrics and in the gut microbiota.




Sex/Gender-Specific Medicine in the Gastrointestinal Diseases


Book Description

Sex/gender - specific medicine (SGM) is defined as the practice of medicine based on the understanding that biology and social roles are important in men and women for disease prevention, screening, diagnosis, and treatment. Current research demonstrates differences in disease incidence, symptomatology, morbidity, and mortality based on sex and gender. Sex/gender-specific medicine is a fundamental aspect of tailored therapy and precision medicine. Therefore, the variables must be considered in medical education and practice as well as in research models ranging from human participants, animals and cells. Gastroenterology is very big and important division of Internal Medicine, which include esophagus, stomach, small and large intestine, pancreatobiliary tract and liver. Nowadays estrogen is known to play a key role in the prevention of colon cancer and progression of liver cirrhosis and hepatocellular carcinoma, especially in women. This book covers the sex/gender-specific medicine in the area of gastrointestinal (GI) tract in the adults as well as in the pediatrics and in the gut microbiota.




Exploring the Biological Contributions to Human Health


Book Description

It's obvious why only men develop prostate cancer and why only women get ovarian cancer. But it is not obvious why women are more likely to recover language ability after a stroke than men or why women are more apt to develop autoimmune diseases such as lupus. Sex differences in health throughout the lifespan have been documented. Exploring the Biological Contributions to Human Health begins to snap the pieces of the puzzle into place so that this knowledge can be used to improve health for both sexes. From behavior and cognition to metabolism and response to chemicals and infectious organisms, this book explores the health impact of sex (being male or female, according to reproductive organs and chromosomes) and gender (one's sense of self as male or female in society). Exploring the Biological Contributions to Human Health discusses basic biochemical differences in the cells of males and females and health variability between the sexes from conception throughout life. The book identifies key research needs and opportunities and addresses barriers to research. Exploring the Biological Contributions to Human Health will be important to health policy makers, basic, applied, and clinical researchers, educators, providers, and journalists-while being very accessible to interested lay readers.




Sex Differences in Physiology


Book Description

Sex Differences in Physiology is an all-encompassing reference that details basic science research into sex differences in all physiological fields. It includes scientific discoveries concerning sex differences in cardiovascular, respiratory, renal, gastrointestinal, and musculoskeletal physiology. In addition, coverage of the development, endocrinology, neurophysiology, immunity, and metabolism is included, making this important reference a resource that will meet the needs of investigators interested in incorporating sex differences into their research programs, while also providing clinicians with the basis for providing the best sex-based medical treatment options available. Provides a sweeping, organ-by-organ review of currently observed sex differences in animal models and human disease Explains how sex differences influence physiology and disease Provides the critical knowledge on sex differences for better understanding of prevention and treatment of diseases







How Sex and Gender Impact Clinical Practice


Book Description

How Sex and Gender Impact Clinical Practice: An Evidence-Based Guide to Patient Care enables primary care clinicians by providing a framework to understand differences and better care for patients in their practice. Each chapter covers a subspecialty in medicine and discusses the influence of sex hormones on disease, along with sex and gender-based differences in clinical presentation, physical examination, laboratory results, treatment regimens, comorbidities and prognosis. Illustrative case examples and practical practice points help each chapter come alive. A special chapter on communication differences between men and women assists clinicians in their conversations with patients. This book fills an important need by applying years of research findings to sex and gender specific medical care and demonstrating that an individualized approach to patient care will lead to improved detection, treatment and prevention of disease. Explores the effects of sex and gender on disease presentation, treatment and prognosis, and how these differences influence clinical decision-making Provides practical guidance that helps clinicians implement a more individualized approach to patient care Contains information on diseases in each major specialty, as well as chapters on communication, pharmacology and public health challenges




Hospital-Based Health Technology Assessment


Book Description

A timely work describing how localized hospital-based health technology assessment (HB-HTA) complements general, ‘arms-length’ HTA agency efforts, and what has been the collective global impact of HB-HTA across the globe. While HB-HTA has gained significant momentum over the past few years, expertise in the field, and information on the operation and organization of HB-HTA, has been scattered. This book serves to bring this information together to inform those who are currently working in the field of HTA at the hospital, regional, national or global level. In addition, this book is intended for decision-makers and policy-makers with a stake in determining the uptake and decommissioning of new and established technologies in the hospital setting. HTA has traditionally been performed at the National/Regional level by HTA Agencies, typically linked to governments. Yet hospitals are the main entry door for most health technologies (HTs). Hospital decision-makers must undertake multiple high stakes investment and disinvestment decisions annually for innovative HTs, usually without adequate information. Despite the existence of arms-length HTA Agencies, inadequate information is available to hospital decision-makers either because relevant HTA reports are not yet released at the time of entry of new technologies to the field, or because even when the report exists, the information contained is insufficient to clarify the contextualized informational needs of hospital decision makers. Therefore, there has recently been a rising trend toward hospital-based HTA units and programs. These units/programs complement the work of National/Regional HTA Agencies by providing the key and relevant evidence needed by hospital decision makers in their specific hospital context, and within required decision-making timelines. The emergence of HB-HTA is creating a comprehensive HTA ecosystem across health care levels, which creates better bridges for knowledge translation through relevance and timeliness.




Sex and Gender Aspects in Clinical Medicine


Book Description

This book is a concise, easy to read professional text with a focus on practical aspects. All chapters include tables on sex/gender differences in symptoms and management and a series of suggestions to the novice in the field. Chapters are specialty-specific. The focus is not on women’s health, but the presentation of differences in clinical symptoms, management and outcomes in women and men. Gender Medicine strives to employ the knowledge about these differences to improve diagnosis, better understand pathogenesis and advance patient-oriented therapy.




Principles of Gender-Specific Medicine


Book Description

The field of gender-specific medicine examines how normal human biology and physiology differ between men and women and how the diagnosis and treatment of disease differs as a function of gender. This revealing research covers various conditions that predominantly occur in men as well conditions that predominantly occur in women. Among the areas of greatest difference are cardiovascular disease, mood disorders, the immune system, lung cancer as a consequence of smoking, osteoporosis, diabetes, obesity, and infectious diseases. The Second Edition of Principles of Gender-Specific Medicine focuses on the essentials of gender-specific medicine and the current study of sex and gender differences in human physiology and pathophysiology. New section editors, new chapter authors, and new chapters have been added to reflect the most up-to-date clinical research and practice. - Offers insight into how the gender-specific risks of one organ system's disease affects the health of other organ systems - Outlines the sex-specific differences of normal anatomy and physiology - Illustrates the gender-specific features and quantifies "gender" and "sex" as risk factors across all major diseases - Qualifies and analyzes the results of new drug therapies designed with gender-specific differences in mind: ex, hormone therapy in men and women for the prevention and treatment of cardiovascular disease - All chapters progress translationally from the basic science to the clinical applications of gender-specific therapies, drugs, or treatments - Sections on drug metabolism, aging, and meta-analysis of data incorporated into all disease-specific chapters




Drug Safety


Book Description