Sinusoidal Cells in Liver Diseases


Book Description

Sinusoidal Cells in Liver Diseases: Role in their Pathophysiology, Diagnosis, and Treatment provides a state-of-the-art review on recent advances surrounding the role of liver sinusoidal cells (LSECs, HSCs, macrophages, and other non-parenchymal cells) in acute and chronic liver diseases. Coverage emphasizes disease pathophysiology, novel mechanisms, unmet clinical questions, development of biomarkers and treatment opportunities. By focusing on the role of sinusoidal cells in human liver diseases, this reference provides a comprehensive overview of the role of sinusoidal cells in acute and chronic liver diseases, in its pathophysiology and mechanisms, and in the development of novel biomarkers and new therapeutics. Cells of the liver vasculature play an essential role in the pathophysiology of acute and chronic liver diseases and are considered key therapeutic targets to treat most of human hepatopathies. Coverage in this reference includes the phenotypic changes occurring in liver vascular cells and how cells contribute to the development of microcirculatory dysfunction, fibrosis, inflammation, and liver failure. - Provides a comprehensive update on the role of sinusoidal cells in acute and chronic liver diseases - Covers our current understanding of the role of sinusoidal cells as therapeutic targets to improve liver diseases - Presents the latest research in the development of novel biomarkers of liver diseases that derive from sinusoidal cells




Mathematics of the Discrete Fourier Transform (DFT)


Book Description

"The DFT can be understood as a numerical approximation to the Fourier transform. However, the DFT has its own exact Fourier theory, and that is the focus of this book. The DFT is normally encountered as the Fast Fourier Transform (FFT)--a high-speed algorithm for computing the DFT. The FFT is used extensively in a wide range of digital signal processing applications, including spectrum analysis, high-speed convolution (linear filtering), filter banks, signal detection and estimation, system identification, audio compression (such as MPEG-II AAC), spectral modeling sound synthesis, and many others. In this book, certain topics in digital audio signal processing are introduced as example applications of the DFT"--Back cover




Liver Diseases and Hepatic Sinusoidal Cells


Book Description

Hepatic sinusoidal cells such as sinusoidal endothelial cells, Kupffer cells, hepatic stellate cells, and pit cells play an important role in hemodynamic and metabolic function and are involved in various liver diseases. The frequent involvement of sinusoidal cells in pathologic conditions is explained by the diverse actions of those cells, an understanding of which is essential to clinicians. Generously illustrated, this volume presents results of recent studies on hepatic sinusoidal cells in liver diseases, with an introduction to the structure and function of the various types of sinusoidal cells. The in-depth focus of the book is on the role of hepatic sinusoidal cells in relation to liver injury and regeneration, hepatic sinusoidal microcirculation, alcoholic liver diseases, hepatic fibrosis, liver tumor, liver transplantation, cholestasis, and congenital lipidosis, thus providing a valuable reference source for practitioners and researchers.




Precalculus with Trigonometry


Book Description

Precalculus with Trigonometry: Concepts and Applications







Vascular Disorders of the Liver


Book Description

This book provides a comprehensive account on individually rare, but collectively frequent diseases of the liver. In the first part, conditions such as hepatic vascular malformations, ischemic cholangiopathy, hepatic artery occlusion, sinusoidal conditions and Budd-Chiari syndrome are discussed among others. The second part examines the causes of vascular liver disease namely, coagulation disorders, neoplasm disorders, non-malignant blood disorders, systemic diseases and toxins, among others. The unique expertise of the authors, who are all members of the Vascular Liver Disease Disorders Group, an independent network of researchers with a common interest in Vascular Liver Diseases, are merged for an optimal pragmatic and individualized approach. This book is of interest to a broad range of experts, such as hepatologists, internists, radiologists and angiologists.




Introduction to Digital Signal Processing


Book Description

"This book offers an introduction to digital signal processing (DSP) with an emphasis on audio signals and computer music ... This book is designed for both technically and musically inclined readers alike--folks with a common goal of exploring digital signal processing"--Page 4 of cover.




Preclinical Speech Science


Book Description

Preclinical Speech Science: Anatomy, Physiology, Acoustics, and Perception, Third Edition is a high-quality text for undergraduate and graduate courses in speech and hearing science. Written in a user-friendly style by distinguished scientists/clinicians who have taught the course to thousands of students at premier academic programs, it is the text of choice for instructors and students. Additionally, it is applicable to a broad range of courses that cover the anatomy and physiology of speech production, speech acoustics, and swallowing as well as those that cover the hearing mechanism, psychoacoustics, and speech perception. The material in this book is designed to help future speech-language pathologists and audiologists to understand the science that underpins their work and provide a framework for the evaluation and management of their future clients. It provides all the information students need to be fully ready for their clinical practicum training. KEY FEATURES: Describes scientific principles explicitly and in translational terms that emphasize their relevance to clinical practice.Features beautiful original, full-color illustrations designed to be instructive learning tools.Incorporates analogies that aid thinking about processes from different perspectives.Features "sidetracks" that contain clinical insights and relate interesting historical and contemporary facts to the discipline of speech and hearing science.Provides a framework for conceptualizing the uses, subsystems, and levels of observation of speech production, hearing, and swallowing.Includes material that is ideal for preparing both undergraduates and graduates for clinical study. NEW TO THE THIRD EDITION: Three new, up-to-date, and comprehensive chapters on auditory anatomy and physiology, auditory psychophysics, and speech physiology measurement and analysis.All chapters fully revised, including updated references and new full-color, detailed images.*Disclaimer: Please note that ancillary content (such as documents, audio, and video, etc.) may not be included as published in the original print version of this book.




Portal Hypertension


Book Description

Portal hypertension is the abnormal pathophysiologic state that develops in liver cirrhosis and certain other disorders with characteristic clinical and hemodynamic features. There has been great progress in our under standing and management of portal hypertension, particularly in the diagnostic and therapeutic approaches. The so-called Banti's syndrome, a disorder whose existence had long been questioned, is now a well-defined portal hypertensive disease. The recently introduced Doppler ftowmetry is currently yielding new information on portal hemodynamics. Endoscopic sclerotherapy and beta-blockers have come to be widely used in the man agement and prevention of variceal bleeding. In spite of all these advances, a number of unsolved questions remain, such as whether sclerotherapy, pharmacotherapy or surgery is warranted for prevention of bleeding, which is more effective as an elective treatment, the surgical or endoscopic approach, and whether surgical portacaval shunt should be totally replaced by selective shunt operations. These new developments and problems are clearly and comprehensively described and discussed by the foremost authorities in 44 chapters, which are divided into five sections: 1) Patho physiology, 2) Hemodynamic Investigations, 3) Imaging Investigations, 4) Clinical and Pathological Features, and 5) Esophageal and Gastrointestinal Bleeding. The primary goal of this monograph, to provide a framework of patho physiology of portal hypertension with authoritative descriptions of the clinical and laboratory manifestations of various portal hypertensive dis orders, has clearly been achieved by these excellent contributions.




Circuits, Signals, and Systems for Bioengineers


Book Description

Accompanying CD-ROM contains ... "MATLAB-based solutions software." -- p. [1] of cover.




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