Anatomy and Physiology


Book Description




Mechanisms of Vascular Disease


Book Description

New updated edition first published with Cambridge University Press. This new edition includes 29 chapters on topics as diverse as pathophysiology of atherosclerosis, vascular haemodynamics, haemostasis, thrombophilia and post-amputation pain syndromes.




The Vascular Smooth Muscle Cell


Book Description

In the last several years, the development of reagents that recognize smooth muscle-specific proteins has enabled researchers to identify smooth muscle cells (SMC) in tissue undergoing both differentiation and repair. These developments have led to increased research on SMC. The latest volume in the Biology of the Extracellular Matrix Series takes a current and all-encompassing look at this growing area of research. Devoted entirely to the subject of SMC, the book covers a diversity of topics-from SMC architecture and contractility to differentiation and gene expression in development. It also examines the proliferation and replication of SMC and its role in pharmacology and vascular disease. A must for cell, developmental, and molecular biologists, this book also will appeal to cardiologists, pathologists, and biomedical researchers interested in smooth muscle cells. - Presents a molecular, genetic, and developmental perspective of the vas smooth muscle cell - Overview sections highlight key points of chapters, including the clinical relevance of the research and expectations for future study - Appeals to both the basic biologist and to the biomedical researcher of vascular disease




Keynes & Aidley's Nerve and Muscle


Book Description

Editions previous to this one had R.D. Keynes and David J. Aidley as primary and secondary authors.




Anatomy & Physiology


Book Description

A version of the OpenStax text




Signal Transduction and Smooth Muscle


Book Description

All hollow organs, such as blood vessels, the gastrointestinal tract, airways, male and female reproductive systems, and the urinary bladder are primarily composed of smooth muscle. Such organs regulate flow, propulsion and mixing of luminal contents and storage by the contraction and relaxation of smooth muscle cells. Smooth muscle cells respond to numerous inputs, including pressure, shear stress, intrinsic and extrinsic innervation, hormones and other circulating molecules, as well as autocrine and paracrine factors. This book is a review of smooth muscle cell regulation in the cardiovascular, reproductive, GI, and other organ systems with emphasis on calcium and receptor signaling. Key selling features: Focuses on smooth muscles of different types Describes ion channel signaling mechanisms Reviews calcium and receptor signaling Includes novel, cutting-edge methodologies Summarizes studies of mice with genetically encoding sensors in smooth muscle Chapter 9 of this book is freely available as a downloadable Open Access PDF under a CC-BY 4.0 license. https://s3-us-west-2.amazonaws.com/tandfbis/rt-files/docs/Open+Access+Chapters/9781498774222_oachapter9.pdf




Ultrastructure of Smooth Muscle


Book Description

Recent advances in electron microscopy have opened up new dimensions and perspectives in the field of morphology, and these are presently being integrated with biochemical and physiopathological phenomena occurring in cells, tissues, and organs. Methods such as freeze-fracture, freeze-etching, scanning, and high-voltage electron microscopy have contributed immensely to this progress, as well as to the study of smooth muscle tissue and contractile cells in general. The articles composing this book have been selected and edited with the purpose of updating and reviewing the most important aspects of smooth muscle cells as revealed by the integration of these submicroscopic techniques. The chapters of this volume have been prepared by some of the most authoritative experts in the discipline. Therefore each article not only offers the reader a concise review of the specific topic, but also seeks to highlight areas that require further investigation. Much of the volume is presented in an illustrative format so as to emphasize the remarkable results obtainable by the combination of the aforementioned methods, which allow a better appreciation of smooth muscle structure and ultrastructure. This volume, like others in the series, is intended not only for researchers in the field, but also for graduate students of histology, embryology, anatomy, physiology, and pathology in both medical and veterinary colleges. My hope is that this book will prove to be a valuable academic resource to the audience of the world in this fascinating and expanding field.




Gastrointestinal Motility


Book Description

The basis of this book is a ten-lecture course on the control of gastrointesti nal motility given each year to the final year undergraduate students in Physiology at Sheffield University. A naive thought led me to believe that the conversion of my lecture notes into the present book would be a relatively easy task. I now know differently. As there is no equivalent undergraduate course elsewhere that I know of, it would be dishonest of me to claim this book to be an undergraduate text. The comprehensive way in which I have dealt with the subject, together with the inclusion of the most up-to-date material, make the book more relevant to postgraduate students of physiology, medicine and related sciences who require an introduction to the field of gastrointestinal motility and its control. I have, however, attempted to present the current concepts on the physiological mechanisms regulating motility in a way which under graduates, as well as postgraduates, will find readable, informative and, hopefully, enjoyable.




Fundamentals of Anaesthesia


Book Description

The second edition of Fundamentals of Anaesthesia builds upon the success of the first edition, and encapsulates the modern practice of anaesthesia in a single volume. Written and edited by a team of expert contributors, it provides a comprehensive but easily readable account of all of the information required by the FRCA Primary examination candidate and has been expanded to include more detail on all topics and to include new topics now covered in the examination. As with the previous edition, presentation of information is clear and concise, with the use of lists, tables, summary boxes and line illustrations where necessary to highlight important information and aid the understanding of complex topics. Great care has been taken to ensure an unrivalled consistency of style and presentation throughout.




Biochemistry of Smooth Muscle Contraction


Book Description

This valuable resource provides a systematic account of the biochemistry of smooth muscle contraction. As a comprehensive guide to this rapidly growing area of research, it covers the structure and characteristic properties of contractile and regulatory proteins, with special emphasis on their predicted function in the live muscle. Also included in this book are intermediate filament proteins, and desmin and vimentin, whose function in smooth muscle is unknown; and several enzymes involved in the phosphorylation-dephosphorylation of contractile and other proteins.