Author : Pauline M. H. Mazumdar
Publisher : Cambridge University Press
Page : 480 pages
File Size : 49,92 MB
Release : 2002-07-18
Category : Science
ISBN : 9780521525237
An account of scientific disputes over the core problems of research and practice in immunology.
Author : Pauline Margaret Hodgson Mazumdar
Publisher :
Page : 457 pages
File Size : 50,75 MB
Release : 1995
Category : Immunology
ISBN :
Their science was designed only in part to wrest an answer from nature: it was at least as important to wring an admission of defeat from their opponents. One of the key figures in the debate was the Austrian immunochemist Karl Landsteiner, whose career provides the central focus for Mazumdar's account. His unitarian views excluded him from promotion within European institutions, where the specificity and pluralism espoused by Robert Koch and Paul Ehrlich were entrenched. Landsteiner himself was forced into a kind of exile at Rockefeller University in New York. Though Landsteiner won a Nobel prize for his work, his inability to gain more widespread acceptance of his views caused him to view his life as a failure.
Author : Masakazu Konishi
Publisher :
Page : pages
File Size : 16,95 MB
Release : 1970
Category :
ISBN :
Author : Kenneth Murphy
Publisher : Garland Science
Page : pages
File Size : 26,80 MB
Release : 2010-06-22
Category : Medical
ISBN : 9780815344575
The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.
Author : Tore Hultin
Publisher :
Page : 0 pages
File Size : 26,3 MB
Release :
Category :
ISBN :
Author : Robert Kovelman
Publisher :
Page : 70 pages
File Size : 33,17 MB
Release : 1970
Category :
ISBN :
Author : National Research Council
Publisher : National Academies Press
Page : 200 pages
File Size : 48,54 MB
Release : 2011-12-05
Category : Science
ISBN : 0309220424
For many years, experiments using chimpanzees have been instrumental in advancing scientific knowledge and have led to new medicines to prevent life-threatening and debilitating diseases. However, recent advances in alternate research tools have rendered chimpanzees largely unnecessary as research subjects. The Institute of Medicine, in collaboration with the National Research Council, conducted an in-depth analysis of the scientific necessity for chimpanzees in NIH-funded biomedical and behavioral research. The committee concludes that while the chimpanzee has been a valuable animal model in the past, most current biomedical research use of chimpanzees is not necessary, though noted that it is impossible to predict whether research on emerging or new diseases may necessitate chimpanzees in the future.
Author : Steven A. Frank
Publisher : Princeton University Press
Page : 364 pages
File Size : 40,64 MB
Release : 2002-07-21
Category : Medical
ISBN : 9780691095950
Publisher Description
Author : Hervé Tettelin
Publisher : Springer Nature
Page : 311 pages
File Size : 25,40 MB
Release : 2020-04-30
Category : Science
ISBN : 3030382818
This open access book offers the first comprehensive account of the pan-genome concept and its manifold implications. The realization that the genetic repertoire of a biological species always encompasses more than the genome of each individual is one of the earliest examples of big data in biology that opened biology to the unbounded. The study of genetic variation observed within a species challenges existing views and has profound consequences for our understanding of the fundamental mechanisms underpinning bacterial biology and evolution. The underlying rationale extends well beyond the initial prokaryotic focus to all kingdoms of life and evolves into similar concepts for metagenomes, phenomes and epigenomes. The book’s respective chapters address a range of topics, from the serendipitous emergence of the pan-genome concept and its impacts on the fields of microbiology, vaccinology and antimicrobial resistance, to the study of microbial communities, bioinformatic applications and mathematical models that tie in with complex systems and economic theory. Given its scope, the book will appeal to a broad readership interested in population dynamics, evolutionary biology and genomics.
Author : National Research Council
Publisher : National Academies Press
Page : 348 pages
File Size : 21,50 MB
Release : 2000-12-21
Category : Nature
ISBN : 0309070864
Scientific Frontiers in Developmental Toxicology and Risk Assessment reviews advances made during the last 10-15 years in fields such as developmental biology, molecular biology, and genetics. It describes a novel approach for how these advances might be used in combination with existing methodologies to further the understanding of mechanisms of developmental toxicity, to improve the assessment of chemicals for their ability to cause developmental toxicity, and to improve risk assessment for developmental defects. For example, based on the recent advances, even the smallest, simplest laboratory animals such as the fruit fly, roundworm, and zebrafish might be able to serve as developmental toxicological models for human biological systems. Use of such organisms might allow for rapid and inexpensive testing of large numbers of chemicals for their potential to cause developmental toxicity; presently, there are little or no developmental toxicity data available for the majority of natural and manufactured chemicals in use. This new approach to developmental toxicology and risk assessment will require simultaneous research on several fronts by experts from multiple scientific disciplines, including developmental toxicologists, developmental biologists, geneticists, epidemiologists, and biostatisticians.
