Industrial Statistics


Book Description

HELPS YOU FULLY LEVERAGE STATISTICAL METHODS TO IMPROVE INDUSTRIAL PERFORMANCE Industrial Statistics guides you through ten practical statistical methods that have broad applications in many different industries for enhancing research, product design, process design, validation, manufacturing, and continuous improvement. As you progress through the book, you'll discover some valuable methods that are currently underutilized in industry as well as other methods that are often not used correctly. With twenty-five years of teaching and consulting experience, author Anand Joglekar has helped a diverse group of companies reduce costs, accelerate product development, and improve operations through the effective implementation of statistical methods. Based on his experience working with both clients and students, Dr. Joglekar focuses on real-world problem-solving. For each statistical method, the book: Presents the most important underlying concepts clearly and succinctly Minimizes mathematical details that can be delegated to a computer Illustrates applications with numerous practical examples Offers a "Questions to Ask" section at the end of each chapter to assist you with implementation The last chapter consists of 100 practical questions followed by their answers. If you're already familiar with statistical methods, you may want to take the test first to determine which methods to focus on. By helping readers fully leverage statistical methods to improve industrial performance, this book becomes an ideal reference and self-study guide for scientists, engineers, managers and other technical professionals across a wide range of industries. In addition, its clear explanations and examples make it highly suited as a textbook for undergraduate and graduate courses in statistics.




The Career of a Research Statistician


Book Description

This monograph highlights the connection between the theoretical work done by research statisticians and the impact that work has on various industries. Drawing on decades of experience as an industry consultant, the author details how his contributions have had a lasting impact on the field of statistics as a whole. Aspiring statisticians and data scientists will be motivated to find practical applications for their knowledge, as they see how such work can yield breakthroughs in their field. Each chapter highlights a consulting position the author held that resulted in a significant contribution to statistical theory. Topics covered include tracking processes with change points, estimating common parameters, crossing fields with absorption points, military operations research, sampling surveys, stochastic visibility in random fields, reliability analysis, applied probability, and more. Notable advancements within each of these topics are presented by analyzing the problems facing various industries, and how solving those problems contributed to the development of the field. The Career of a Research Statistician is ideal for researchers, graduate students, or industry professionals working in statistics. It will be particularly useful for up-and-coming statisticians interested in the promising connection between academia and industry.




Statistics


Book Description

This - one of a kind - book offers a comprehensive, almost encyclopedic presentation of statistical methods and analytic approaches used in science, industry, business, and data mining, written from the perspective of the real-life practitioner ("consumer") of these methods.




Statistics In the Pharmaceutical Industry, 3rd Edition


Book Description

The growth of the pharmaceutical industry over the past decade is astounding, but the impact of this growth on statistics is somewhat confusing. While software has made analysis easier and more efficient, regulatory bodies now demand deeper and more complex analyses, and pharmacogenetic/genomic studies serve up an entirely new set of challenges. For more than two decades, Statistics in the Pharmaceutical Industry has been the definitive guide to sorting through the challenges in the industry, and this Third Edition continues that tradition. Updated and expanded to reflect the most recent trends and developments in the field, Statistics in the Pharmaceutical Industry, Third Edition presents chapters written by experts from both regulatory agencies and pharmaceutical companies who discuss everything from experimental design to post-marketing studies. This approach sheds light on what regulators consider acceptable methodologies and what methods have proven successful for industrial statisticians. Both new and revised chapters reflect the increasingly global nature of the industry as represented by authors from Japan and Europe, the increasing trend toward non-inferiority/equivalence testing, adaptive design in clinical trials, global harmonization of regulatory standards, and multiple comparison studies. The book also examines the latest considerations in anti-cancer studies. Statistics in the Pharmaceutical Industry, Third Edition demystifies the approval process by combining regulatory and industrial points of view, making it a must-read for anyone performing statistical analysis at any point in the drug approval process.




The Role of Statistics in Business and Industry


Book Description

An insightful guide to the use of statistics for solving key problems in modern-day business and industry This book has been awarded the Technometrics Ziegel Prize for the best book reviewed by the journal in 2010. Technometrics is a journal of statistics for the physical, chemical and engineering sciences, published jointly by the American Society for Quality and the American Statistical Association. Criteria for the award include that the book brings together in one volume a body of material previously only available in scattered research articles and having the potential to significantly improve practice in engineering and science. Highlighting the relevance of statistical methods in everyday applications, The Role of Statistics in Business and Industry bridges the gap between the tools of statistics and their use in today's business world. This one-of-a-kind resource encourages the proactive use of statistics in three well-organized and succinct parts: Setting the Stage provides an introduction to statistics, with a general overview of its uses in business and industry Manufactured Product Applications explains how statistical techniques assist in designing, building, improving, and ensuring the reliability of a wide variety of manufactured products such as appliances, plastic materials, aircraft engines, and locomotives Other Applications describe the role of statistics in pharmaceuticals, finance, and business services, as well as more specialized areas including the food, semiconductor, and communications industries This book is truly unique in that it first describes case studies and key business problems, and then shows how statistics is used to address them, while most literature on the topic does the reverse. This approach provides a comprehensive understanding of common issues and the most effective methods for their treatment. Each chapter concludes with general questions that allow the reader to test their understanding of the presented statistical concepts as well as technical questions that raise more complex issues. An extensive FTP site provides additional material, including solutions to some of the applications. With its accessible style and real-world examples, The Role of Statistics in Business and Industry is a valuable supplement for courses on applied statistics and statistical consulting at the upper-undergraduate and graduate levels. It is also an ideal resource for early-career statisticians and practitioners who would like to learn the value of applying statistics to their everyday work.







Nonclinical Statistics for Pharmaceutical and Biotechnology Industries


Book Description

This book serves as a reference text for regulatory, industry and academic statisticians and also a handy manual for entry level Statisticians. Additionally it aims to stimulate academic interest in the field of Nonclinical Statistics and promote this as an important discipline in its own right. This text brings together for the first time in a single volume a comprehensive survey of methods important to the nonclinical science areas within the pharmaceutical and biotechnology industries. Specifically the Discovery and Translational sciences, the Safety/Toxiology sciences, and the Chemistry, Manufacturing and Controls sciences. Drug discovery and development is a long and costly process. Most decisions in the drug development process are made with incomplete information. The data is rife with uncertainties and hence risky by nature. This is therefore the purview of Statistics. As such, this book aims to introduce readers to important statistical thinking and its application in these nonclinical areas. The chapters provide as appropriate, a scientific background to the topic, relevant regulatory guidance, current statistical practice, and further research directions.




Applied Data Mining


Book Description

Data mining can be defined as the process of selection, explorationand modelling of large databases, in order to discover models andpatterns. The increasing availability of data in the currentinformation society has led to the need for valid tools for itsmodelling and analysis. Data mining and applied statistical methodsare the appropriate tools to extract such knowledge from data.Applications occur in many different fields, including statistics,computer science, machine learning, economics, marketing andfinance. This book is the first to describe applied data mining methodsin a consistent statistical framework, and then show how they canbe applied in practice. All the methods described are eithercomputational, or of a statistical modelling nature. Complexprobabilistic models and mathematical tools are not used, so thebook is accessible to a wide audience of students and industryprofessionals. The second half of the book consists of nine casestudies, taken from the author's own work in industry, thatdemonstrate how the methods described can be applied to realproblems. Provides a solid introduction to applied data mining methods ina consistent statistical framework Includes coverage of classical, multivariate and Bayesianstatistical methodology Includes many recent developments such as web mining,sequential Bayesian analysis and memory based reasoning Each statistical method described is illustrated with real lifeapplications Features a number of detailed case studies based on appliedprojects within industry Incorporates discussion on software used in data mining, withparticular emphasis on SAS Supported by a website featuring data sets, software andadditional material Includes an extensive bibliography and pointers to furtherreading within the text Author has many years experience teaching introductory andmultivariate statistics and data mining, and working on appliedprojects within industry A valuable resource for advanced undergraduate and graduatestudents of applied statistics, data mining, computer science andeconomics, as well as for professionals working in industry onprojects involving large volumes of data - such as in marketing orfinancial risk management.




Applied Statistics in the Pharmaceutical Industry


Book Description

Providing a general guide to statistical methods used in the pharmaceutical industry, and illustrating how to use S-PLUS to implement these methods, the book explains why S-PLUS is a useful software package and discusses the results and implications of each particular application. It is targeted at graduates in biostatistics, statisticians involved in the industry as research scientists, regulators, academics, and/or consultants who want to know more about how to use S-PLUS and learn about other sub-fields within the industry, as well as statisticians in other fields who want to know more about statistical applications in the pharmaceutical industry.




Scan Statistics


Book Description

In many statistical applications, scientists have to analyze the occurrence of observed clusters of events in time or space. Scientists are especially interested in determining whether an observed cluster of events has occurred by chance if it is assumed that the events are distributed independently and uniformly over time or space. Scan statistics have relevant applications in many areas of science and technology including geology, geography, medicine, minefield detection, molecular biology, photography, quality control and reliability theory and radio-optics.