Aza-bridged Bicyclic Amines from (2-azaallyl)stannanes and the Total Synthesis of (+)-cocaine
Author : Douglas M. Mans
Publisher :
Page : 522 pages
File Size : 50,19 MB
Release : 2004
Category :
ISBN :
Author : Douglas M. Mans
Publisher :
Page : 522 pages
File Size : 50,19 MB
Release : 2004
Category :
ISBN :
Author : Hans Ulrich Blaser
Publisher : John Wiley & Sons
Page : 517 pages
File Size : 45,98 MB
Release : 2011-08-04
Category : Science
ISBN : 3527642161
This second edition of the pioneering work on this hot topic captures the major trends and latest achievements in the art of asymmetric catalysis on an industrial scale. A number of completely new real-life case studies written by the world leaders in their respective areas provide a compact and qualified insight into this developing field. The resulting ready reference and handbook collates first-hand and valuable information within a context where it can be easily found. The high-quality contributions illustrate the relevant environments and situations, such as time pressure, how the catalytic step fits into the overall synthesis, or competition with other synthetic approaches, as well as the typical problems encountered in the various phases, including finding/developing the catalyst and optimization of the process or choice of equipment. Both successful and unsuccessful approaches to solve these problems are described.
Author : Nir Qvit
Publisher : Academic Press
Page : 792 pages
File Size : 10,91 MB
Release : 2022-09-22
Category : Science
ISBN : 0128204478
Peptide and Peptidomimetic Therapeutics: From Bench to Beside offers applied, evidence-based instruction on developing and applying peptide therapeutics in disease treatment, driving drug discovery, and improving patient care. Here, researchers, clinicians and students will find tools to harness the full power of peptides and peptidomimetics and improve bioavailability, stability, efficiency and selectivity of new therapeutics and their application in treatment plans. More than 20 leaders in the field share their approaches for identifying and advancing peptide and peptidomimetic therapeutics. Topics examined run from "bench to bedside," beginning with fundamental peptide science, protein-protein interactions and peptide synthesis. Later chapters examine modes for peptide drug delivery, including cell penetration peptide and peptidomimetic delivery, as well as the targeting of specific disease types, peptide therapeutics as applied to infectious disease, cancer, metabolic disorders, neurodegenerative disorders, and skin disorders, and antiparasitic and immunosuppressive peptidomimetics. - Helps researchers and clinicians harness the full of power of peptides and peptidomimetics in their daily work and drug discovery - Features chapters running from "bench to bedside, providing a thorough grounding in fundamental peptide science, drug delivery methods, and targeting of specific disease types - Features chapter contributions from international leaders in peptide science and drug development
Author : Tamio Hayashi
Publisher : CRC Press
Page : 408 pages
File Size : 16,26 MB
Release : 1998-06-09
Category : Science
ISBN : 9789056991524
This volume provides a comprehensive overview of the rapidly developing field of asymmetric synthesis. Using easy to understand graphical abstracts it presents 348 important catalytic and stoichiometric reactions leading to the synthesis of optically active chiral compounds. The first part of the book covers reactions related to reductions, oxidations, carbon-carbon bond formation and carbon-heteroatom bond formation. Each graphical abstract is accompanied by a list of important keywords and references to assist the reader. The second part concentrates on experimental aspects, describing synthetic procedures for selected chiral reagents and chiral auxiliaries, and provides an invaluable reference tool for laboratory work. Written with both the graduate student and professional organic chemist in mind, this book will serve as an important resource for the synthetic organic chemist.
Author : Douglass F. Taber
Publisher : John Wiley & Sons
Page : 240 pages
File Size : 28,61 MB
Release : 2008-08-20
Category : Science
ISBN : 0470385960
The second volume in a series, Organic Synthesis: State of the Art 2005-2007 will provide you with a convenient, compact summary of the state of the art of organic synthesis. This reference guide will quickly lead you to the most important recent developments like how scientists can now prepare ketones by directly combining aldehydes with terminal alkenes. Inside, you will find detailed analysis of more than twenty total syntheses, including the Davies Synthesis of (-)-Colombiasin A and (-)-Elisapterosin B, the Overman Synthesis of (-)-Sarain A, and the Sorensen Synthesis of (-)-Guanacastepene E.
Author : Martin H. Osterhout
Publisher :
Page : 756 pages
File Size : 34,32 MB
Release : 1992
Category :
ISBN :
Author : Alfred Hassner
Publisher : Elsevier
Page : 462 pages
File Size : 17,56 MB
Release : 2013-10-22
Category : Science
ISBN : 1483287343
Synthetically useful organic reactions or reagents are often referred to by the name of the discoverer(s) or developer(s). Older name reactions are described in text books, but more recently developed synthetically useful reactions that may have been associated occasionally with a name are not always well known. For neither of the above are experimental procedures or references easy to find. In this monograph approximately 500 name reactions are included, of which over 200 represent newer name reactions and modern reagents. Each of these reactions are extremely useful for the contemporary organic chemistry researcher in industry or academic institutions. This book provides the information in an easily accessible form. In addition to seminal references and reviews, one or more examples for each name reaction are provided and a complete typical experimental procedure is included, to enable the student or researcher to immediately evaluate reaction conditions. Besides an alphabetical listing of reactions and reagents, cross references permit the organic practitioner to find those name reactions or reagents that enable specific transformations, such as, conversion of amines to nitriles, stereoselective reduction, fluoroalkylation, phenol alkynylation, asymmetric syntheses, allylic alkylation, nucleoside synthesis, cyclopentanation, hydrozirconation, to name a few. Emphasis has been placed on stereoselective and regioselective transformations as well as on enantioselective processes. The listing of reactions and reagents is supported by four indexes.
Author : Laszlo Kurti
Publisher : Elsevier
Page : 808 pages
File Size : 11,89 MB
Release : 2005-04-29
Category : Science
ISBN : 0080575412
Kurti and Czako have produced an indispensable tool for specialists and non-specialists in organic chemistry. This innovative reference work includes 250 organic reactions and their strategic use in the synthesis of complex natural and unnatural products. Reactions are thoroughly discussed in a convenient, two-page layout--using full color. Its comprehensive coverage, superb organization, quality of presentation, and wealth of references, make this a necessity for every organic chemist. - The first reference work on named reactions to present colored schemes for easier understanding - 250 frequently used named reactions are presented in a convenient two-page layout with numerous examples - An opening list of abbreviations includes both structures and chemical names - Contains more than 10,000 references grouped by seminal papers, reviews, modifications, and theoretical works - Appendices list reactions in order of discovery, group by contemporary usage, and provide additional study tools - Extensive index quickly locates information using words found in text and drawings
Author :
Publisher :
Page : 398 pages
File Size : 12,68 MB
Release : 2009
Category : Dissertations, Academic
ISBN :
Author : American Chemical Society
Publisher :
Page : 1256 pages
File Size : 41,43 MB
Release : 2004
Category : Chemistry
ISBN :