The Immortal Life of Henrietta Lacks


Book Description

#1 NEW YORK TIMES BESTSELLER • “The story of modern medicine and bioethics—and, indeed, race relations—is refracted beautifully, and movingly.”—Entertainment Weekly NOW A MAJOR MOTION PICTURE FROM HBO® STARRING OPRAH WINFREY AND ROSE BYRNE • ONE OF THE “MOST INFLUENTIAL” (CNN), “DEFINING” (LITHUB), AND “BEST” (THE PHILADELPHIA INQUIRER) BOOKS OF THE DECADE • ONE OF ESSENCE’S 50 MOST IMPACTFUL BLACK BOOKS OF THE PAST 50 YEARS • WINNER OF THE CHICAGO TRIBUNE HEARTLAND PRIZE FOR NONFICTION NAMED ONE OF THE BEST BOOKS OF THE YEAR BY The New York Times Book Review • Entertainment Weekly • O: The Oprah Magazine • NPR • Financial Times • New York • Independent (U.K.) • Times (U.K.) • Publishers Weekly • Library Journal • Kirkus Reviews • Booklist • Globe and Mail Her name was Henrietta Lacks, but scientists know her as HeLa. She was a poor Southern tobacco farmer who worked the same land as her slave ancestors, yet her cells—taken without her knowledge—became one of the most important tools in medicine: The first “immortal” human cells grown in culture, which are still alive today, though she has been dead for more than sixty years. HeLa cells were vital for developing the polio vaccine; uncovered secrets of cancer, viruses, and the atom bomb’s effects; helped lead to important advances like in vitro fertilization, cloning, and gene mapping; and have been bought and sold by the billions. Yet Henrietta Lacks remains virtually unknown, buried in an unmarked grave. Henrietta’s family did not learn of her “immortality” until more than twenty years after her death, when scientists investigating HeLa began using her husband and children in research without informed consent. And though the cells had launched a multimillion-dollar industry that sells human biological materials, her family never saw any of the profits. As Rebecca Skloot so brilliantly shows, the story of the Lacks family—past and present—is inextricably connected to the dark history of experimentation on African Americans, the birth of bioethics, and the legal battles over whether we control the stuff we are made of. Over the decade it took to uncover this story, Rebecca became enmeshed in the lives of the Lacks family—especially Henrietta’s daughter Deborah. Deborah was consumed with questions: Had scientists cloned her mother? Had they killed her to harvest her cells? And if her mother was so important to medicine, why couldn’t her children afford health insurance? Intimate in feeling, astonishing in scope, and impossible to put down, The Immortal Life of Henrietta Lacks captures the beauty and drama of scientific discovery, as well as its human consequences.




Study Guide: the Immortal Life of Henrietta Lacks by Rebecca Skloot (SuperSummary)


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SuperSummary, a modern alternative to SparkNotes and CliffsNotes, offers high-quality study guides for challenging works of literature. This 38-page guide for "The Immortal Life of Henrietta Lacks" by Rebecca Skloot includes detailed chapter summaries and analysis covering 38 chapters, as well as several more in-depth sections of expert-written literary analysis. Featured content includes commentary on major characters, 10 important quotes, discussion topics, and key themes like Scientific Ethics and Informed Consent.




Summary and Analysis of The Immortal Life of Henrietta Lacks


Book Description

So much to read, so little time? Get an in-depth summary of The Immortal Life of Henrietta Lacks, the #1 bestseller about science, race, and medical ethics. For decades, scientists have been using “HeLa” cells in biological research, from developing the polio vaccine and studying the nature of cancer to observing how human biology behaves in outer space. This famous cell line began as a sample taken from a poor African American mother of five named Henrietta Lacks. A cancer patient, Henrietta Lacks went through medical testing but never gave consent for the use of her cells. She died of cervical cancer in 1951, without ever knowing that the samples were intended for extensive medical research. This summary of the #1 New York Times bestseller by Rebecca Skloot tells Henrietta’s story and reveals what happened when her family found out that her cells were being bought and sold in labs around the world. With historical context, character profiles, a timeline of key events, and other features, this summary and analysis of The Immortal Life of Henrietta Lacks is intended to complement your reading experience and bring you closer to a great work of nonfiction.




A Conspiracy of Cells


Book Description

A Conspiracy of Cells presents the first full account of one of medical science's more bizarre and costly mistakes. On October 4, 1951, a young black woman named Henrietta Lacks died of cervical cancer. That is, most of Henrietta Lacks died. In a laboratory dish at the Johns Hopkins Medical Center in Baltimore, a few cells taken from her fatal tumor continued to live--to thrive, in fact. For reasons unknown, her cells, code-named "HeLa," grew more vigorously than any other cells in culture at the time. Long-time science reporter Michael Gold describes in graphic detail how the errant HeLa cells spread, contaminating and overwhelming other cell cultures, sabotaging research projects, and eluding detection until they had managed to infiltrate scientific laboratories worldwide. He tracks the efforts of geneticist Walter Nelson-Rees to alert a sceptical scientific community to the rampant HeLa contamination. And he reconstructs Nelson-Rees's crusade to expose the embarrassing mistakes and bogus conclusions of researchers who unknowingly abetted HeLa's spread.




Hidden Valley Road


Book Description

#1 NEW YORK TIMES BESTSELLER • OPRAH’S BOOK CLUB PICK • ONE OF GQ's TOP 50 BOOKS OF LITERARY JOURNALISM IN THE 21st CENTURY • The heartrending story of a midcentury American family with twelve children, six of them diagnosed with schizophrenia, that became science's great hope in the quest to understand the disease. "Reads like a medical detective journey and sheds light on a topic so many of us face: mental illness." —Oprah Winfrey Don and Mimi Galvin seemed to be living the American dream. After World War II, Don's work with the Air Force brought them to Colorado, where their twelve children perfectly spanned the baby boom: the oldest born in 1945, the youngest in 1965. In those years, there was an established script for a family like the Galvins--aspiration, hard work, upward mobility, domestic harmony--and they worked hard to play their parts. But behind the scenes was a different story: psychological breakdown, sudden shocking violence, hidden abuse. By the mid-1970s, six of the ten Galvin boys, one after another, were diagnosed as schizophrenic. How could all this happen to one family? What took place inside the house on Hidden Valley Road was so extraordinary that the Galvins became one of the first families to be studied by the National Institute of Mental Health. Their story offers a shadow history of the science of schizophrenia, from the era of institutionalization, lobotomy, and the schizophrenogenic mother to the search for genetic markers for the disease, always amid profound disagreements about the nature of the illness itself. And unbeknownst to the Galvins, samples of their DNA informed decades of genetic research that continues today, offering paths to treatment, prediction, and even eradication of the disease for future generations. With clarity and compassion, bestselling and award-winning author Robert Kolker uncovers one family's unforgettable legacy of suffering, love, and hope.




Hacking Darwin


Book Description

"A gifted and thoughtful writer, Metzl brings us to the frontiers of biology and technology, and reveals a world full of promise and peril." — Siddhartha Mukherjee MD, New York Times bestselling author of The Emperor of All Maladies and The Gene A groundbreaking exploration of genetic engineering and its impact on the future of our species from leading geopolitical expert and technology futurist, Jamie Metzl. At the dawn of the genetics revolution, our DNA is becoming as readable, writable, and hackable as our information technology. But as humanity starts retooling our own genetic code, the choices we make today will be the difference between realizing breathtaking advances in human well-being and descending into a dangerous and potentially deadly genetic arms race. Enter the laboratories where scientists are turning science fiction into reality. In this captivating and thought-provoking nonfiction science book, Jamie Metzl delves into the ethical, scientific, political, and technological dimensions of genetic engineering, and shares how it will shape the course of human evolution. Cutting-edge insights into the field of genetic engineering and its implications for humanity's future Explores the transformative power of genetic technologies and their potential to reshape human life Examines the ethical considerations surrounding genetic engineering and the choices we face as a species Engaging narrative that delves into the scientific breakthroughs and real-world applications of genetic technologies Provides a balanced perspective on the promises and risks associated with genetic engineering Raises thought-provoking questions about the future of reproduction, human health, and our relationship with nature Drawing on his extensive background in genetics, national security, and foreign policy, Metzl paints a vivid picture of a world where advancements in technology empower us to take control of our own evolution, but also cautions against the pitfalls and ethical dilemmas that could arise if not properly managed. Hacking Darwin is a must-read for anyone interested in the intersection of science, technology, and humanity's future.




The Rules of Contagion


Book Description

An Observer Book of the Year A Times Science Book of the Year A New Statesman Book of the Year A Financial Times Science Book of the Year 'Astonishingly bold' Daily Mail 'It is hard to imagine a more timely book ... much of the modern world will make more sense having read it.' The Times We live in a world that's more interconnected than ever before. Our lives are shaped by outbreaks - of disease, of misinformation, even of violence - that appear, spread and fade away with bewildering speed. To understand them, we need to learn the hidden laws that govern them. From 'superspreaders' who might spark a pandemic or bring down a financial system to the social dynamics that make loneliness catch on, The Rules of Contagion offers compelling insights into human behaviour and explains how we can get better at predicting what happens next. Along the way, Adam Kucharski explores how innovations spread through friendship networks, what links computer viruses with folk stories - and why the most useful predictions aren't necessarily the ones that come true. Now revised and updated with content on Covid-19.




Typhoid Mary


Book Description

Discover the forgotten story of Mary Mallon—the real Typhoid Mary—in this humanizing portrait offering a window into the ethical dilemmas of public health policy that continue to haunt us in the COVID era. She was an Irish immigrant cook. Between 1900 and 1907, she infected 22 New Yorkers with typhoid fever through her puddings and cakes; one of them died. Tracked down through epidemiological detective work, she was finally apprehended as she hid behind a barricade of trashcans. To protect the public's health, authorities isolated her on Manhattan’s North Brother Island, where she died some 30 years later. This book tells the remarkable story of Mary Mallon—the real Typhoid Mary. Combining social history with biography, historian Judith Leavitt re-creates early 20th-century New York City, a world of strict class divisions and prejudice against immigrants and women. Leavitt engages the reader with the excitement of the early days of microbiology and brings to life the conflicting perspectives of journalists, public health officials, the law, and Mary Mallon herself. Leavitt’s readable account illuminates dilemmas that continue to haunt us in the age of COVID-19. To what degree are we willing to sacrifice individual liberty to protect the public's health? How far should we go? For anyone who is concerned about the threats and quandaries posed by new epidemics, Typhoid Mary is a vivid reminder of the human side of disease and disease control.




Crisis in the Red Zone


Book Description

NEW YORK TIMES BESTSELLER • An urgent wake-up call about the future of emerging viruses and a gripping account of the doctors and scientists fighting to protect us, told through the story of the deadly 2013–2014 Ebola epidemic “Crisis in the Red Zone reads like a thriller. That the story it tells is all true makes it all more terrifying.”—Elizabeth Kolbert, Pulitzer Prize–winning author of The Sixth Extinction From the #1 bestselling author of The Hot Zone, now a National Geographic original miniseries . . . This time, Ebola started with a two-year-old child who likely had contact with a wild creature and whose entire family quickly fell ill and died. The ensuing global drama activated health professionals in North America, Europe, and Africa in a desperate race against time to contain the viral wildfire. By the end—as the virus mutated into its deadliest form, and spread farther and faster than ever before—30,000 people would be infected, and the dead would be spread across eight countries on three continents. In this taut and suspenseful medical drama, Richard Preston deeply chronicles the pandemic, in which we saw for the first time the specter of Ebola jumping continents, crossing the Atlantic, and infecting people in America. Rich in characters and conflict—physical, emotional, and ethical—Crisis in the Red Zone is an immersion in one of the great public health calamities of our time. Preston writes of doctors and nurses in the field putting their own lives on the line, of government bureaucrats and NGO administrators moving, often fitfully, to try to contain the outbreak, and of pharmaceutical companies racing to develop drugs to combat the virus. He also explores the charged ethical dilemma over who should and did receive the rare doses of an experimental treatment when they became available at the peak of the disaster. Crisis in the Red Zone makes clear that the outbreak of 2013–2014 is a harbinger of further, more severe outbreaks, and of emerging viruses heretofore unimagined—in any country, on any continent. In our ever more interconnected world, with roads and towns cut deep into the jungles of equatorial Africa, viruses both familiar and undiscovered are being unleashed into more densely populated areas than ever before. The more we discover about the virosphere, the more we realize its deadly potential. Crisis in the Red Zone is an exquisitely timely book, a stark warning of viral outbreaks to come.




The Wordy Shipmates


Book Description

From the author of Lafayette in the Somewhat United States, The Wordy Shipmates is New York Times bestselling author Sarah Vowell's exploration of the Puritans and their journey to America to become the people of John Winthrop's "city upon a hill," a shining example, a "city that cannot be hid." To this day, America views itself as a Puritan nation, but Vowell investigates what that means? and what it should mean. What was this great political enterprise all about? Who were these people who are considered the philosophical, spiritual, and moral ancestors of our nation? What Vowell discovers is something far different from what their uptight shoe-buckles-and- corn reputation might suggest. The people she finds are highly literate, deeply principled, and surprisingly feisty. Their story is filled with pamphlet feuds, witty courtroom dramas, and bloody vengeance. Along the way she asks: *Was Massachusetts Bay Colony governor John Winthrop a communitarian, a Christlike Christian, or conformity?s tyrannical enforcer? Answer: Yes! *Was Rhode Island?s architect, Roger Williams, America?s founding freak or the father of the First Amendment? Same difference. *What does it take to get that jezebel Anne Hutchinson to shut up? A hatchet. *What was the Puritans? pet name for the Pope? The Great Whore of Babylon. Sarah Vowell?s special brand of armchair history makes the bizarre and esoteric fascinatingly relevant and fun. She takes us from the modern-day reenactment of an Indian massacre to the Mohegan Sun casino, from old-timey Puritan poetry, where ?righteousness? is rhymed with ?wilderness,? to a Mayflower-themed waterslide. Throughout, The Wordy Shipmates is rich in historical fact, humorous insight, and social commentary by one of America?s most celebrated voices. Thou shalt enjoy it.