Author : Sergio Serrano-Villar
Publisher : Frontiers Media SA
Page : 228 pages
File Size : 43,35 MB
Release : 2023-05-12
Category : Medical
ISBN : 2832523366
Author : Cong-Jun Li
Publisher : Nova Science Pub Incorporated
Page : 331 pages
File Size : 38,16 MB
Release : 2014-01-01
Category : Science
ISBN : 9781631176579
This is the first book specifically devoted to butyrate and its biological functions in the health of humans and animals. It is the result of the collective efforts of a group of international experts working on different aspects of butyrate. It has been recognised for a long time that the consumption of dietary fibres has positive metabolic health effects. These effects are directly associated with short-chain fatty acids (SCFAs), particularly butyrate, formed by the microbial degradation of dietary fibres in the digestive tract. Butyrate-induced biological effects provide examples of epigenomic regulation induced by nutrient elements and provide a basis for understanding the full range of the biological roles and molecular mechanisms that butyrate may play in cell growth, proliferation and energy metabolism. This book is a comprehensive collection of highly innovative research ideas, strategies, and crucial points related to butyrate and its biological functions. With a detailed introduction of recent advances in different but intriguing research fields, this book is a great reference for biochemists, molecular biologists, biomedical scientists and clinical researchers. This book is also a great reference for graduate students working in the related fields of biomedical sciences.
Author : Brian D. Gulbransen
Publisher : Biota Publishing
Page : 72 pages
File Size : 10,66 MB
Release : 2014-07-01
Category : Medical
ISBN : 1615046615
The enteric nervous system (ENS) is a complex neural network embedded in the gut wall that orchestrates the reflex behaviors of the intestine. The ENS is often referred to as the “little brain” in the gut because the ENS is more similar in size, complexity and autonomy to the central nervous system (CNS) than other components of the autonomic nervous system. Like the brain, the ENS is composed of neurons that are surrounded by glial cells. Enteric glia are a unique type of peripheral glia that are similar to astrocytes of the CNS. Yet enteric glial cells also differ from astrocytes in many important ways. The roles of enteric glial cell populations in the gut are beginning to come to light and recent evidence implicates enteric glia in almost every aspect of gastrointestinal physiology and pathophysiology. However, elucidating the exact mechanisms by which enteric glia influence gastrointestinal physiology and identifying how those roles are altered during gastrointestinal pathophysiology remain areas of intense research. The purpose of this e-book is to provide an introduction to enteric glial cells and to act as a resource for ongoing studies on this fascinating population of glia. Table of Contents: Introduction / A Historical Perspective on Enteric Glia / Enteric Glia: The Astroglia of the Gut / Molecular Composition of Enteric Glia / Development of Enteric Glia / Functional Roles of Enteric Glia / Enteric Glia and Disease Processes in the Gut / Concluding Remarks / References / Author Biography
Author : Sashwati Roy
Publisher : CRC Press
Page : 463 pages
File Size : 41,2 MB
Release : 2012-09-17
Category : Medical
ISBN : 1439872155
Although acute inflammation is a healthy physiological response indicative of wound healing, chronic inflammation has been directly implicated in a wide range of degenerative human health disorders encompassing almost all present day non-communicable diseases including autoimmune diseases, obesity, diabetes and atherosclerosis. Chronic Inflammation
Author : Bharat B. Aggarwal
Publisher : Springer
Page : 489 pages
File Size : 15,64 MB
Release : 2014-05-12
Category : Medical
ISBN : 3034808372
This volume examines in detail the role of chronic inflammatory processes in the development of several types of cancer. Leading experts describe the latest results of molecular and cellular research on infection, cancer-related inflammation and tumorigenesis. Further, the clinical significance of these findings in preventing cancer progression and approaches to treating the diseases are discussed. Individual chapters cover cancer of the lung, colon, breast, brain, head and neck, pancreas, prostate, bladder, kidney, liver, cervix and skin as well as gastric cancer, sarcoma, lymphoma, leukemia and multiple myeloma.
Author : Mark Lyte
Publisher : Springer
Page : 440 pages
File Size : 21,28 MB
Release : 2014-07-05
Category : Science
ISBN : 1493908979
The field of microbial endocrinology is expressly devoted to understanding the mechanisms by which the microbiota (bacteria within the microbiome) interact with the host (“us”). This interaction is a two-way street and the driving force that governs these interactions are the neuroendocrine products of both the host and the microbiota. Chapters include neuroendocrine hormone-induced changes in gene expression and microbial endocrinology and probiotics. This is the first in a series of books dedicated to understanding how bi-directional communication between host and bacteria represents the cutting edge of translational medical research, and hopefully identifies new ways to understand the mechanisms that determine health and disease.
Author : Dirk Haller
Publisher : Springer
Page : 355 pages
File Size : 40,68 MB
Release : 2018-07-27
Category : Medical
ISBN : 3319905457
The book provides an overview on how the gut microbiome contributes to human health. The readers will get profound knowledge on the connection between intestinal microbiota and immune defense systems. The tools of choice to study the ecology of these highly-specialized microorganism communities such as high-throughput sequencing and metagenomic mining will be presented. In addition the most common diseases associated to the composition of the gut flora are discussed in detail. The book will address researchers, clinicians and advanced students working in biomedicine, microbiology and immunology.
Author : Severin Ringoir
Publisher : Springer Science & Business Media
Page : 292 pages
File Size : 20,21 MB
Release : 2012-12-06
Category : Science
ISBN : 1468454455
The present book contains the Proceedings of a two day Symposium on Uremic Toxins organized at the University of Ghent in Belgium. A series of guest lectures, free communications and posters have been presented. An international audience of 163 scientists from 16 nationalities listened to and discussed extensively a spectrum of topics brought forward by colleagues and researchers who worked for many years in the field of Uremic Toxins. There is a striking contrast between all the new dialysis strategies available in the work to "clean" the uremic patients and the almost non-progression of our knowledge on uremic toxins in the past decade. In this sense the symposium was felt by all participants as a new start for the research in the biochemical field of the definition of uremia. If the present volume would stimulate new work in this field in order to define uremia, or identify the uremic toxins, the purpose of the organizers would be maximally fulfilled.
Author : Mark Lyte
Publisher : Springer
Page : 316 pages
File Size : 37,53 MB
Release : 2010-10-22
Category : Medical
ISBN : 9781441956026
Microbial endocrinology represents a newly emerging interdisciplinary field that is formed by the intersection of the fields of neurobiology and microbiology. This book will introduce a new perspective to the current understanding not only of the factors that mediate the ability of microbes to cause disease, but also to the mechanisms that maintain normal homeostasis. The discovery that microbes can directly respond to neuroendocrine hormones, as evidenced by increased growth and production of virulence-associated factors, provides for a new framework with which to investigate how microorganisms interface not only with vertebrates, but also with invertebrates and even plants. The reader will learn that the neuroendocrine hormones that one most commonly associates with mammals are actually found throughout the plant, insect and microbial communities to an extent that will undoubtedly surprise many, and most importantly, how interactions between microbes and neuroendocrine hormones can influence the pathophysiology of infectious disease.
Author : National Academies of Sciences, Engineering, and Medicine
Publisher : National Academies Press
Page : 133 pages
File Size : 47,34 MB
Release : 2017-07-19
Category : Science
ISBN : 0309458390
The 21st century has witnessed a complete revolution in the understanding and description of bacteria in eco- systems and microbial assemblages, and how they are regulated by complex interactions among microbes, hosts, and environments. The human organism is no longer considered a monolithic assembly of tissues, but is instead a true ecosystem composed of human cells, bacteria, fungi, algae, and viruses. As such, humans are not unlike other complex ecosystems containing microbial assemblages observed in the marine and earth environments. They all share a basic functional principle: Chemical communication is the universal language that allows such groups to properly function together. These chemical networks regulate interactions like metabolic exchange, antibiosis and symbiosis, and communication. The National Academies of Sciences, Engineering, and Medicine's Chemical Sciences Roundtable organized a series of four seminars in the autumn of 2016 to explore the current advances, opportunities, and challenges toward unveiling this "chemical dark matter" and its role in the regulation and function of different ecosystems. The first three focused on specific ecosystemsâ€"earth, marine, and humanâ€"and the last on all microbiome systems. This publication summarizes the presentations and discussions from the seminars.
