Author : OECD
Publisher : OECD Publishing
Page : 21 pages
File Size : 47,57 MB
Release : 2002-04-24
Category :
ISBN : 9264070648
This method provides information on health hazard likely to arise from exposure to test substance (liquids, solids and aerosols) by application on the eye. This Test Guideline is intended preferably for use with albino rabbit. The test substance is ...
Author : OECD
Publisher : OECD Publishing
Page : 13 pages
File Size : 37,72 MB
Release : 2023-07-04
Category :
ISBN : 926418533X
This method provides information on health hazard likely to arise from exposure to test substance (liquids, solids and aerosols) by application on the eye. This Test Guideline is intended preferably for use with albino rabbit. The test substance is ...
Author : Organisation for Economic Co-operation and Development
Publisher : Organisation for Economic Co-operation and Development ; [Montréal : Renouf]
Page : pages
File Size : 18,99 MB
Release : 1981
Category : Chemical industry
ISBN : 9789264122215
Author :
Publisher : Columbia Books. Incorporated
Page : 532 pages
File Size : 33,96 MB
Release : 2015
Category : Medical
ISBN :
The Globally Harmonized System of Classification and Labelling of Chemicals (GHS) addresses classification and labelling of chemicals by types of hazards. It provides the basis for worldwide harmonization of rules and regulations on chemicals and aims at enhancing the protection of human health and the environment during their handling, transport and use by ensuring that the information about their physical, health and environmental hazards is available. The sixth revised edition includes, inter alia, a new hazard class for desensitized explosives and a new hazard category for pyrophoric gases; miscellaneous amendments intended to further clarify the criteria for some hazard classes (explosives, specific target organ toxicity following single exposure, aspiration hazard, and hazardous to the aquatic environment) and to complement the information to be included in section 9 of the Safety Data Sheet; revised and further rationalized precautionary statements; and an example of labelling of a small packaging in Annex 7.
Author : Christoph A. Reinhardt
Publisher : John Wiley & Sons
Page : 200 pages
File Size : 24,73 MB
Release : 2008-11-20
Category : Science
ISBN : 3527616047
Opinion leaders in science and politics examine findings and legislation in alternatives to animal testing! Refine, reduce, replace - These are the three demands that scientists have placed upon themselves in their search for alternatives to animal testing. Indeed much interdisciplinary research is being carried on today, and new fields have emerged, such as in-vitro toxicology. The three R's call for new scientific insights. Moreover, validation and acceptance strategies have to be adapted, a process of much ongoing interest and vital concern to the pharmaceutical and cosmetic industries. Researchers need to know exactly what has been achieved and accepted in alternatives to animal testing in science and politics. In this book they have the opportunity to benefit from the knowledge and expertise of leading researchers and influential representatives of national and international regulatory authorities.
Author : Mr. Khushal B. Chaudhari, Dr. Yogesh V. Ushir
Publisher : Shashwat Publication
Page : 153 pages
File Size : 24,23 MB
Release : 2024-09-28
Category : Medical
ISBN : 9360879711
This book, Practical Pharmacology-III for B.Pharm students, covers all the practical aspects of Pharmacology-III in the PCI syllabus. It focuses on the preclinical screening methods, OECD guidelines for toxicity testing in animals, bioassays and biostatistical calculations.
Author : Rakesh Kumar Tekade
Publisher : Elsevier
Page : 754 pages
File Size : 26,32 MB
Release : 2023-03-23
Category : Medical
ISBN : 044315841X
Toxicity and Toxicodynamics, Volume One in the Essentials of Pharmatoxicology in Drug Research series provides an overview on the essentials of toxicology, risk assessment and the mechanisms. Topics discussed include the types of cellular responses to chemical toxicants, mechanisms of drug toxicity, and their relevance to pharmaceutical product development. The book examines omics and computer-aided technologies for mechanistic and predictive toxicology and covers state-of-art testing in the evaluation of detrimental pathways, dose selection in toxicity studies, as well as the role of regulatory agencies in toxicity studies. In addition, there is also discussion on clinical interventions such as pharmacotherapy and managed care strategies for acute poisoning. This volume is a valuable resource to those learning more about the drug development process related to toxicology and those who want to get an update on newer concepts on the toxicology aspect of drug research. - Examines toxicological risk assessment in drug research - Discusses toxicity mechanisms - Covers risk assessment and the use of omics and computational technologies in mechanistic and predictive toxicology - Offers clinical interventions and managed care as a result of toxic injury and acute poisoning
Author :
Publisher :
Page : 442 pages
File Size : 31,10 MB
Release : 2012-06
Category : Delegated legislation
ISBN :
Author : Kathryn Bayne
Publisher : Academic Press
Page : 335 pages
File Size : 45,8 MB
Release : 2013-09-02
Category : Medical
ISBN : 0123851041
Laboratory Animal Welfare provides a comprehensive, up-to-date look into the new science of animal welfare within laboratory research. Animals specifically considered include rodents, cats and dogs, nonhuman primates, agricultural animals, avian animals and aquatic animals. The book examines the impact of experiment design and environment on animal welfare, as well as emergency situations and euthanasia practices. Readers will benefit from a review of regulations and policy guidelines concerning lab animal use, as well as information on assessing animal welfare. With discussions of the history and ethics of animals in research, and a debate on contemporary and international issues, this book is a go-to resource for laboratory animal welfare.
Author : Byung-Mu Lee
Publisher : CRC Press
Page : 664 pages
File Size : 12,25 MB
Release : 2017-09-07
Category : Medical
ISBN : 1315391694
Continuing a long tradition, Lu‘s Basic Toxicology, Seventh Edition, provides guidance on principles of toxicology and testing procedures for toxicities as well as a concise yet detailed mechanism of both target organ and non-target organ toxicities. The book also addresses the toxic effects of chemicals and risk assessment, giving students and practicing toxicologists, the tools to enhance their practice. This edition includes new chapters on Systems Toxicology, Chemicals and Children, Toxicology of Reproductive Systems, providing the essentials of these topics in the same style as other chapters in the book. Separate subject and chemical indexes make this a useful, quick shelf reference.
