The Basal Ganglia III


Book Description

This volume represents the collected papers presented at the Third Triennial Symposium of the International Basal Ganglia society (IBAGS) held at Capo Boi, Italy, June 10-13, 1989. About 300 members of the society and participants attended the symposium which was held in a delightful environment conducive to the formal and informal exchange of scientific thought. The interdisciplinary nature of the symposium was unique in its coverage of the neurosciences from molecular biology to clinical and behavioural studies. The 80 papers collected here reflect the wide spectrum and the depth of studies on virtually all aspects of the basal ganglia. Unfortunately, this book does not capture the cordial and congenial atmosphere which has characterized this, and all prior symposia of the Society. Any cooperative endeavour of this kind requires a tremendous effort and dedication, usually by a small number of individuals. The Society is especially pleased to acknowledge the support and encouragement of the "Italian Ministry of university and Scientific Research" and the "Italian National. Research Council". In addition the society received financial support from numerous Foundations and corporations, which are listed separately under acknowledgements. Finally the Editors are pleased that Plenum Press, which has published the two previous symposia, has accepted this program for publication. It is our hope that vast scientific efforts reflected in these pages will be widely disseminated and further encourage every kind of research related to the basal ganglia.




Handbook of Basal Ganglia Structure and Function


Book Description

The Basal Ganglia comprise a group of forebrain nuclei that are interconnected with the cerebral cortex, thalamus and brainstem. Basal ganglia circuits are involved in various functions, including motor control and learning, sensorimotor integration, reward and cognition. The importance of these nuclei for normal brain function and behavior is emphasized by the numerous and diverse disorders associated with basal ganglia dysfunction, including Parkinson’s disease, Tourette’s syndrome, Huntington’s disease, obsessive-compulsive disorder, dystonia, and psychostimulant addiction. The Handbook of Basal Ganglia provides a comprehensive overview of the structural and functional organization of the basal ganglia, with special emphasis on the progress achieved over the last 10-15 years. Organized in six parts, the volume describes the general anatomical organization and provides a review of the evolution of the basal ganglia, followed by detailed accounts of recent advances in anatomy, cellular/molecular, and cellular/physiological mechanisms, and our understanding of the behavioral and clinical aspects of basal ganglia function and dysfunction. Synthesizes widely dispersed information on the behavioral neurobiology of the basal ganglia, including advances in the understanding of anatomy, cell-molecular and cell-physiological mechanisms, and behavioral/clinical aspects of function and dysfunction Features a truly international cast of the preeminent researchers in the field Fully explores the clinically relevant impact of the basal ganglia on various psychiatric and neurological diseases




GABA and the Basal Ganglia


Book Description

Over the past 25 years the amount of data pertaining to the GABAergic function in the basal ganglia has increased dramatically. GABA and the Basal Ganglia - From Molecules to Systems is a comprehensive review of the current state-of-the-art of knowledge about the neuroanatomy, neuropharmacology and neurophysiology of the basal ganglia, focusing on its GABAergic microcircuitry. It serves as a complete reference to the body of knowledge about the basal ganglia, its constituent neurons, and their interconnections. This volume is designed to serve as a convenient all-in-one review and reference for experienced basal ganglia researchers as well as an introduction to the functional organization of the basal ganglia and its GABAergic circuitry for students and researchers new to the field. * Reviews the anatomy, physiology and pharmacology of the basal ganglia itself in addition to focusing on the GABAergic circuitry of the basal ganglia* Authors of each chapter leading internationally acclaimed experts in basal ganglia research




Ontology-Based Information Retrieval for Healthcare Systems


Book Description

With the advancements of semantic web, ontology has become the crucial mechanism for representing concepts in various domains. For research and dispersal of customized healthcare services, a major challenge is to efficiently retrieve and analyze individual patient data from a large volume of heterogeneous data over a long time span. This requirement demands effective ontology-based information retrieval approaches for clinical information systems so that the pertinent information can be mined from large amount of distributed data. This unique and groundbreaking book highlights the key advances in ontology-based information retrieval techniques being applied in the healthcare domain and covers the following areas: Semantic data integration in e-health care systems Keyword-based medical information retrieval Ontology-based query retrieval support for e-health implementation Ontologies as a database management system technology for medical information retrieval Information integration using contextual knowledge and ontology merging Collaborative ontology-based information indexing and retrieval in health informatics An ontology-based text mining framework for vulnerability assessment in health and social care An ontology-based multi-agent system for matchmaking patient healthcare monitoring A multi-agent system for querying heterogeneous data sources with ontologies for reducing cost of customized healthcare systems A methodology for ontology based multi agent systems development Ontology based systems for clinical systems: validity, ethics and regulation




Integrated Systems of the CNS, Part III


Book Description

This book represents the third part of Integrated Systems of the CNS in the Handbook of Chemical Neuroanatomy. Part I is concerned with limbic regions and the hypothalamus, as well as with the retina. Part II contains reviews of central pathways associated with four major sensory systems. Part III is dedicated to W.J.H. Nauta, best remembered for the first selective silver implantation technique for dealing with degenerating axons. The volume is divided into three sections: the cerebellum, chemoarchitecture and anatomy; the basal ganglia; and the olfactory system. An excellent volume to keep pace with this challenging and rapidly developing field.




Neurobiology of Sensation and Reward


Book Description

Synthesizing coverage of sensation and reward into a comprehensive systems overview, Neurobiology of Sensation and Reward presents a cutting-edge and multidisciplinary approach to the interplay of sensory and reward processing in the brain. While over the past 70 years these areas have drifted apart, this book makes a case for reuniting sensation a







Models of Information Processing in the Basal Ganglia


Book Description

This book brings together the biology and computational features of the basal ganglia and their related cortical areas along with select examples of how this knowledge can be integrated into neural network models. Recent years have seen a remarkable expansion of knowledge about the anatomical organization of the part of the brain known as the basal ganglia, the signal processing that occurs in these structures, and the many relations both to molecular mechanisms and to cognitive functions. This book brings together the biology and computational features of the basal ganglia and their related cortical areas along with select examples of how this knowledge can be integrated into neural network models. Organized in four parts - fundamentals, motor functions and working memories, reward mechanisms, and cognitive and memory operations - the chapters present a unique admixture of theory, cognitive psychology, anatomy, and both cellular- and systems- level physiology written by experts in each of these areas. The editors have provided commentaries as a helpful guide to each part. Many new discoveries about the biology of the basal ganglia are summarized, and their impact on the computational role of the forebrain in the planning and control of complex motor behaviors discussed. The various findings point toward an unexpected role for the basal ganglia in the contextual analysis of the environment and in the adaptive use of this information for the planning and execution of intelligent behaviors. Parallels are explored between these findings and new connectionist approaches to difficult control problems in robotics and engineering. Contributors James L. Adams, P. Apicella, Michael Arbib, Dana H. Ballard, Andrew G. Barto, J. Brian Burns, Christopher I. Connolly, Peter F. Dominey, Richard P. Dum, John Gabrieli, M. Garcia-Munoz, Patricia S. Goldman-Rakic, Ann M. Graybiel, P. M. Groves, Mary M. Hayhoe, J. R. Hollerman, George Houghton, James C. Houk, Stephen Jackson, Minoru Kimura, A. B. Kirillov, Rolf Kotter, J. C. Linder, T. Ljungberg, M. S. Manley, M. E. Martone, J. Mirenowicz, C. D. Myre, Jeff Pelz, Nathalie Picard, R. Romo, S. F. Sawyer, E Scarnat, Wolfram Schultz, Peter L. Strick, Charles J. Wilson, Jeff Wickens, Donald J. Woodward, S. J. Young




The Basal Ganglia IV


Book Description

''Emphasis on new issues and emerging concepts insures that the information presented is still timely...A compelling source of information on recent research in the field.'' ---Journal of Chemical Neuroanatomy, May 1997




Ciba Foundation Symposium


Book Description