Gastro-entero-pancreatic Endocrine System


Book Description

"The majority of the chapters of this volume are based on the papers read in a Symposium on the "GEP Endocrine System" held on 11 and 12 February, 1972, at Ikaho, Japan."




Advances in Metabolic Disorders


Book Description

Advances in Metabolic Disorders, Volume 1 presents the application of biochemistry to the pathogenesis of human diseases. This book discusses the parathormone physiology and its deviations, as well as the origins and course of osteoporosis. The introductory chapters deal with the catabolism of glycogen; physiology of parathyroids; multiple enzymic defects; biochemical technology of glycogen storage disease; assay of parathyroid hormone; mechanisms of mitochondrial respiratory control; pathogenesis of primary osteoporosis; and nature of bone change. The subsequent chapters consider the definition and physiology of insulin antagonists and chemistry of parathyroid hormone. These topics are followed by discussions of the physiologic effects of aldosterone and the metabolic interrelationship between folate and vitamin B12 are presented. A chapter is devoted to the definition and treatment of hypoparathyroidism and hyperparathyroidism. The remaining chapters focus on the diagnosis of insulin antagonists in tissues, plasma, and serum. The book can provide useful information to doctors, students, and researchers.




Fundamentals of Body MRI E-Book


Book Description

Fundamentals of Body MRI—a new title in the Fundamentals of Radiology series—explains and defines key concepts in body MRI so you can confidently make radiologic diagnoses. Dr. Christopher G. Roth presents comprehensive guidance on body imaging—from the liver to the female pelvis—and discusses how physics, techniques, hardware, and artifacts affect results. This detailed and heavily illustrated reference will help you effectively master the complexities of interpreting findings from this imaging modality. Master MRI techniques for the entirety of body imaging, including liver, breast, male and female pelvis, and cardiovascular MRI. Avoid artifacts thanks to extensive discussions of considerations such as physics and parameter tradeoffs. Grasp visual nuances through numerous images and correlating anatomic illustrations.




Integrative Gastroenterology


Book Description

Digestive complaints have become increasingly common. Recent statistics show that gastrointestinal complaints account for nearly a third of all visits to primary care doctors and that nearly one in two Americans suffer from digestive disease. Millions more suffer from conditions such as migraine headaches, arthritis, mood disorders, chronic fatigue, asthma, allergies, and menstrual dysfunction, which are all related to a disorder in digestive health. Despite the evidence in support of integrative approaches to treatment and prevention of digestive symptoms, these approaches are largely overlooked in treating gastrointestinal disorders. Rather, treatment plans tend to be exclusively pharmacologically based and have appreciable toxicity. Integrative Gastroenterology, Second edition, is a comprehensive guide to helping health care practitioners understand and appreciate how to manage patients with gastrointestinal conditions integrating conventional and complimentary approaches. This text reviews the latest advances in science and research with regards to the gut microbiome, physiology, and interconnections between the gut and other organ systems. Coverage includes a diverse range of treatment methods, such as probiotics, meditation, massage, yoga, supplements, special diets, energy medicine, homeopathy, and acupuncture, as well as a special section devoted to mind-body medicine in digestive health and disease. In discussing unconventional treatments, the authors address many of the controversies that surround the remedies.




Gastritis and Gastric Cancer


Book Description

This book is a comprehensive overview of invited contributions on Helicobacter pylori infection in gastritis and gastric carcinogenesis. The first part of the book covers topics related to the pathophysiology of gastric mucosal defense system and gastritis including the gastroprotective function of the mucus, the capsaicin-sensitive afferent nerves and the oxidative stress pathway involved in inflammation, apoptosis and autophagy in H. pylori related gastritis. The next chapters deal with molecular pathogenesis and treatment, which consider the role of neuroendocrine cells in gastric disease, DNA methylation in H. pylori infection, the role of antioxidants and phytotherapy in gastric disease. The final part presents the effects of cancer risk factors associated with H. pylori infection. These chapters discuss the serum pepsinogen test, K-ras mutations, cell kinetics, and H. pylori lipopolysaccharide, as well as the roles of several bacterial genes (cagA, cagT, vacA and dupA) as virulence factors in gastric cancer, and the gastrokine-1 protein in cancer progression.




Drug Discovery and Evaluation: Pharmacological Assays


Book Description

The 4th edition of this successful reference book contains an updated selection of the most frequently used assays for reliably detecting the pharmacological effects of potential drugs. Effects covered include cardiovascular, analgesic, endocrine, psychotropic, respiratory, renal and immunomodulatory activities. Each of the more than 1,000 assays comprises a detailed protocol outlining the purpose and rationale of the method, a critical assessment of the results and their pharmacological and clinical relevance. In addition, animal models of rare diseases are described. For this 4th edition, all existing chapters have been revised and completely updated. A large number of assays were added. Sections that have been specifically enlarged include - Pharmacological assays in thrombosis and haemostasis, - Antidiabetic activity (includes completely new chapters such as Biochemical Methods in Diabetology), - Anti-atherosclerotic activity. New chapters are added such as Auditory Pharmacology, Oncology Activity, Stem Cells, Omics, Personalized Medicine, etc.




Geriatric Gastroenterology


Book Description

As aging trends in the United States and Europe in particular are strongly suggestive of increasingly older society, it would be prudent for health care providers to better prepare for such changes. By including physiology, disease, nutrition, pharmacology, pathology, radiology and other relevant associated topics, Geriatric Gastroenterology fills the void in the literature for a volume devoted specifically to gastrointestinal illness in the elderly. This unique volume includes provision of training for current and future generations of physicians to deal with the health problems of older adults. It will also serve as a comprehensive guide to practicing physicians for ease of reference. Relevant to the geriatric age group, the volume covers epidemiology, physiology of aging, gastrointestinal physiology, pharmacology, radiology, pathology, motility disorders, luminal disorders, hepato-biliary disease, systemic manifestations, neoplastic disorders, gastrointestinal bleeding, cancer and medication related interactions and adverse events, all extremely common in older adults; these are often hard to evaluate and judge, especially considering the complex aging physiology. All have become important components of modern medicine. Special emphasis is be given to nutrition and related disorders. Capsule endoscopy and its utility in the geriatric population is also covered. Presented in simple, easy to read style, the volume includes numerous tables, figures and key points enabling ease of understanding. Chapters on imaging and pathology are profusely illustrated. All chapters are written by specialists and include up to date scientific information. Geriatric Gastroenterology is of great utility to residents in internal medicine, fellows in gastroenterology and geriatric medicine as well as gastroenterologists, geriatricians and practicing physicians including primary care physicians caring for older adults.




Healthy Stomach Initiative


Book Description

This special topic issue of 'Digestive Diseases' contains contributions discussing the subject in-depth. 'Digestive Diseases' is a well-respected, international peer-reviewed journal in Gastroenterology. Special topic issues are included in the subscription.




Morson and Dawson's Gastrointestinal Pathology


Book Description

Morson and Dawson's Gastrointestinal Pathology is one of the 'Gold Standards' of pathology textbooks. It has been completely revised to incorporate the latest advances in this rapidly evolving field including the developments in gastric cancer and Helicobacter pylori and the revised classification of other common gastrointestinal conditions. This new edition features a wealth of new material presented in full colour for the first time.